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anti-TKT antibody :: Rabbit TKT Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9127276
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.1 mL  /  $305 +1 FREE 8GB USB
0.2 mL  /  $460 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TKT, Polyclonal Antibody

 Also Known As   

TKT Polyclonal Antibody

 Product Synonym Names    TK; TKT1; HEL107
 Product Gene Name   

anti-TKT antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    606781
 3D Structure    ModBase 3D Structure for P29401
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Affinity Purification
 Concentration    1mg/ml (lot specific)
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 Species    Human
 Immunogen    Recombinant Protein
 Immunogen    Recombinant protein of human TKT
 Calculated Molecular Weight    67kDa
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 Preparation and Storage    Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
 Other Notes    Small volumes of anti-TKT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-TKT antibody

   This gene encodes a thiamine-dependent enzyme which plays a role in the channeling of excess sugar phosphates to glycolysis in the pentose phosphate pathway. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
 Product Categories/Family for anti-TKT antibody    Polyclonal
 Applications Tested/Suitable for anti-TKT antibody   

Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

 Application Notes for anti-TKT antibody    WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
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 Western Blot (WB) of anti-TKT antibody    Western blot analysis of extracts of various cell lines, using TKT antibody.
anti-TKT antibody Western Blot (WB) (WB) image
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 Immunofluorescence (IF) of anti-TKT antibody    Immunofluorescence analysis of U2OS cell using TKT antibody. Blue: DAPI for nuclear staining.
anti-TKT antibody Immunofluorescence (IF) image
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NCBI/Uniprot data below describe general gene information for TKT. It may not necessarily be applicable to this product.
 NCBI GI #    1729976
 NCBI GeneID    7086
 NCBI Accession #    P29401.3 [Other Products]
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 UniProt Primary Accession #    P29401 [Other Products]
 UniProt Secondary Accession #    Q8TBA3; Q96HH3; A8K089; B4DE31; E7EPA7 [Other Products]
 UniProt Related Accession #    P29401 [Other Products]
 Molecular Weight    623
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 NCBI Official Full Name    Transketolase
 NCBI Official Synonym Full Names    transketolase
 NCBI Official Symbol    TKT [Similar Products]
 NCBI Official Synonym Symbols   
TK; TKT1; HEL107
[Similar Products]
 NCBI Protein Information    transketolase; epididymis luminal protein 107
 UniProt Protein Name    Transketolase
 Protein Family    Transketolase
 UniProt Gene Name    TKT [Similar Products]
 UniProt Synonym Gene Names    TK [Similar Products]
 UniProt Entry Name    TKT_HUMAN
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 NCBI Summary for TKT    This gene encodes a thiamine-dependent enzyme which plays a role in the channeling of excess sugar phosphates to glycolysis in the pentose phosphate pathway. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012]
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 UniProt Comments for TKT    TKT: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. Homodimer. Belongs to the transketolase family.

Protein type: Transferase; EC 2.2.1.1; Carbohydrate Metabolism - pentose phosphate pathway

Chromosomal Location of Human Ortholog: 3p14.3

Cellular Component: nucleoplasm; peroxisome; nucleus; cytosol; vesicle

Molecular Function: transketolase activity; protein homodimerization activity; metal ion binding; cofactor binding

Biological Process: pentose-phosphate shunt; regulation of growth; carbohydrate metabolic process; energy reserve metabolic process; glyceraldehyde-3-phosphate biosynthetic process; pentose-phosphate shunt, non-oxidative branch; xylulose biosynthetic process; pathogenesis

Disease: Wernicke-korsakoff Syndrome
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 Research Articles on TKT    1. Akt1 phosphorylates TKT on Thr382, markedly enhancing enzyme activity.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-TKT antibodyPathways associated with anti-TKT antibody
 Reference Product  PubMed Publications
 PKM2 antibody  >3 publications with TKT and PKM2
 ALDOA antibody  >3 publications with TKT and ALDOA
 RPE antibody  >2 publications with TKT and RPE
 RBKS antibody  >1 publications with TKT and RBKS
 UBC antibody  >1 publications with TKT and UBC
 FBP1 antibody  >1 publications with TKT and FBP1
 Products by Pathway  Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Glycogen Storage Diseases Pathway antibodies  Glycogen Storage Diseases Pathway Diagram
 Insulin Effects Increased Synthesis Of Xylulose-5-Phosphate Pathway antibodies  Insulin Effects Increased Synthesis Of Xylulose-5-Phosphate Pathway Diagram
 Integration Of Energy Metabolism Pathway antibodies  Integration Of Energy Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
Diseases associated with anti-TKT antibodyOrgans/Tissues associated with anti-TKT antibody
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >20 publications with TKT and Carcinoma
 Kidney Diseases Antibodies  >9 publications with TKT and Kidney Diseases
 Adenocarcinoma Antibodies  >8 publications with TKT and Adenocarcinoma
 Nervous System Diseases Antibodies  >6 publications with TKT and Nervous System Diseases
 Liver Diseases Antibodies  >6 publications with TKT and Liver Diseases
 Congenital Abnormalities Antibodies  >5 publications with TKT and Congenital Abnormalities
 Inflammation Antibodies  >4 publications with TKT and Inflammation
 Liver Neoplasms Antibodies  >4 publications with TKT and Liver Neoplasms
 Fatty Liver Antibodies  >3 publications with TKT and Fatty Liver
 Hyperplasia Antibodies  >3 publications with TKT and Hyperplasia
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >16 publications with TKT and Blood
 Eye Antibodies  >14 publications with TKT and Eye
 Liver Antibodies  >13 publications with TKT and Liver
 Kidney Antibodies  >13 publications with TKT and Kidney
 Connective Tissue Antibodies  >9 publications with TKT and Connective Tissue
 Mouth Antibodies  >8 publications with TKT and Mouth
 Bone Antibodies  >7 publications with TKT and Bone
 Brain Antibodies  >6 publications with TKT and Brain
 Skin Antibodies  >5 publications with TKT and Skin
 Embryonic Tissue Antibodies  >4 publications with TKT and Embryonic Tissue
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