Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow TLR1 rightarrow Polyclonal TLR1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Apolipoprotein B - APOB Antibody
 • Calcium-Calmodulin Dependent Protein Kinase Kinase 2 (CAMKK2... ELISA Kit
 • HNF4A Antibody
 • LIG3 Antibody
 • CKMB ELISA Kit
 • CD50 - ICAM-3 (ICAM3) Antibody
 • N (G),N (G)-dimethylarginine dimethylaminohydrolase 2 (Ddah2... Recombinant Protein
 • C3b ELISA Kit
 • CD27 Antibody
 • HEPATITIS A VIRUS Antigen
 • gasdermin D (GSDMD) ELISA Kit
 • Anti-Human Protein C, Clone 1 (PROC) Antibody
 • IL-32a ELISA Kit
 • Immunoglobulin M (IgM) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-TLR1 antibody :: Rabbit TLR1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS540395
Unit / Price
0.1 mg Affinity-Purified  /  $390 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TLR1, Polyclonal Antibody

 Also Known As   

TLR1 Antibody

 Product Synonym Names    CD281; KIAA0012; LPRS5; rsc786; Similar to Drosophila Toll protein; TIL; TIL. LPRS5; Tlr1; Toll (Drosophila) homolog; Toll like receptor 1; Toll/Interleukin 1 receptor like antibody
 Product Gene Name   

anti-TLR1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 3D Structure    ModBase 3D Structure for Q9EPQ1
 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Mouse, Rat
Predicted: Human
Section Bar
 Form/Format    Affinity Purified
 Concentration    0.55-0.67 ug/ul in antibody stabilization buffer (lot specific)
Section Bar
 Immunogen    Synthetic peptide taken within amino acid region 200-250 on mouse toll-like receptor 1 protein.
 Immunoglobulin    IgG
 Molecular Function    Receptor, Transmembrane signaling receptor activity, triacyl lipopeptide binding
 Structure    Binds MYD88 (via TIR domains) (By similarity). Interacts (via extracellular domain) with TLR2. Ligand binding induces the formation of a heterodimer with TLR2 (By similarity). Interacts with CNPY3.
 Subcellular Location    Cell membrane; Single-pass type I membrane protein, Cytoplasmic vesicle ; phagosome membrane; Single-pass type I membrane protein
Section Bar
 Preparation and Storage    -20 degree C for long term storage
 Other Notes    Small volumes of anti-TLR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for anti-TLR1 antibody

   Affinity Purified Toll-like receptor 1 Antibody
Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides.
 Product Categories/Family for anti-TLR1 antibody    Primary Antibodies; Immunology; Innate Immunity; TLR Signaling; TLR1 Antibody
 Applications Tested/Suitable for anti-TLR1 antibody   

ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)

 Application Notes for anti-TLR1 antibody    ELISA: 1:20,000
Immunocytochemistry: 1:100
Immunofluorescence: 1:100
Immunohistochemistry: 1:100
Immunoprecipitation: 1:200
Western Blot: 1:500
Section Bar
 Western Blot (WB) of anti-TLR1 antibody    anti-TLR1 antibody Western Blot (WB) (WB) image
Section Bar
 Immunohistochemistry (IHC) of anti-TLR1 antibody    anti-TLR1 antibody Immunohistochemistry (IHC) (IHC) image
Section Bar
 Immunohistochemistry (IHC) of anti-TLR1 antibody    anti-TLR1 antibody Immunohistochemistry (IHC) (IHC) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for TLR1. It may not necessarily be applicable to this product.
 NCBI GI #    13507603
 NCBI GeneID    21897
 NCBI Accession #    NP_109607.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_030682.2 [Other Products]
Section Bar
 UniProt Primary Accession #    Q9EPQ1 [Other Products]
 UniProt Secondary Accession #    Q9EPW5 [Other Products]
 UniProt Related Accession #    Q9EPQ1 [Other Products]
 Molecular Weight    90,673 Da
Table BarTOPTable Bar
 NCBI Official Full Name    toll-like receptor 1
 NCBI Official Synonym Full Names    toll-like receptor 1
 NCBI Official Symbol    Tlr1 [Similar Products]
 NCBI Protein Information    toll-like receptor 1
 UniProt Protein Name    Toll-like receptor 1
 UniProt Synonym Protein Names   
Toll/interleukin-1 receptor-like protein; TIL; CD_antigen: CD281
 Protein Family    Toll-like receptor
 UniProt Gene Name    Tlr1 [Similar Products]
 UniProt Synonym Gene Names    TIL [Similar Products]
 UniProt Entry Name    TLR1_MOUSE
Section Bar
 UniProt Comments for TLR1    TLR1: Participates in the innate immune response to microbial agents. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Binds MYD88 (via TIR domain). Interacts with CNPY3. Interacts (via extracellular domain) with TLR2. Ligand binding induces the formation of a heterodimer with TLR2. Ubiquitous. Highly expressed in spleen, ovary, peripheral blood leukocytes, thymus and small intestine. Belongs to the Toll-like receptor family.

Protein type: Membrane protein, integral

Cellular Component: cytoplasmic vesicle; Golgi apparatus; integral to membrane; integral to plasma membrane; lipid raft; membrane; phagocytic vesicle; plasma membrane

Molecular Function: protein heterodimerization activity; transmembrane receptor activity; triacylated lipoprotein binding

Biological Process: activation of NF-kappaB-inducing kinase; defense response; defense response to bacterium; detection of triacylated bacterial lipoprotein; immune response; immune system process; inflammatory response; innate immune response; macrophage activation; microglial cell activation; MyD88-dependent toll-like receptor signaling pathway; positive regulation of interleukin-6 biosynthetic process; positive regulation of tumor necrosis factor biosynthetic process; regulation of cytokine secretion; response to bacterial lipoprotein; signal transduction; toll-like receptor 1 signaling pathway; toll-like receptor signaling pathway
Table BarTOPTable Bar
 Research Articles on TLR1    1. Activation of MyD88-dependent TLR1/2 signaling by misfolded alpha-synuclein, a protein linked to neurodegenerative disorders.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-TLR1 antibodyPathways associated with anti-TLR1 antibody
 Reference Product  PubMed Publications
 Tlr2 antibody  >727 publications with TLR1 and Tlr2
 Myd88 antibody  >145 publications with TLR1 and Myd88
 Nod2 antibody  >40 publications with TLR1 and Nod2
 Tirap antibody  >39 publications with TLR1 and Tirap
 Traf6 antibody  >17 publications with TLR1 and Traf6
 Irak2 antibody  >16 publications with TLR1 and Irak2
 Irak1 antibody  >12 publications with TLR1 and Irak1
 Irak4 antibody  >10 publications with TLR1 and Irak4
 Products by Pathway  Pathway Diagram
 Beta Defensins Pathway antibodies  Beta Defensins Pathway Diagram
 Defensins Pathway antibodies  Defensins Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Toll-like Receptor Signaling Pathway antibodies  Toll-like Receptor Signaling Pathway Diagram
 Toll-like Receptor Signaling Pathway antibodies  Toll-like Receptor Signaling Pathway Diagram
 Tuberculosis Pathway antibodies  Tuberculosis Pathway Diagram
 Tuberculosis Pathway antibodies  Tuberculosis Pathway Diagram
Diseases associated with anti-TLR1 antibodyOrgans/Tissues associated with anti-TLR1 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >243 publications with TLR1 and Inflammation
 Necrosis Antibodies  >154 publications with TLR1 and Necrosis
 Lung Diseases Antibodies  >48 publications with TLR1 and Lung Diseases
 Kidney Diseases Antibodies  >22 publications with TLR1 and Kidney Diseases
 Liver Diseases Antibodies  >16 publications with TLR1 and Liver Diseases
 Pneumonia Antibodies  >12 publications with TLR1 and Pneumonia
 Colitis Antibodies  >11 publications with TLR1 and Colitis
 Heart Diseases Antibodies  >11 publications with TLR1 and Heart Diseases
 Leprosy Antibodies  >9 publications with TLR1 and Leprosy
 Neoplasms, Experimental Antibodies  >8 publications with TLR1 and Neoplasms, Experimental
 Organ/Tissue Name  Pubmed Publications
 Other Antibodies  >200 publications with TLR1 and Other
 Bone Marrow Antibodies  >61 publications with TLR1 and Bone Marrow
 Kidney Antibodies  >46 publications with TLR1 and Kidney
 Spleen Antibodies  >45 publications with TLR1 and Spleen
 Intestine Antibodies  >39 publications with TLR1 and Intestine
 Liver Antibodies  >39 publications with TLR1 and Liver
 Skin Antibodies  >37 publications with TLR1 and Skin
 Lymph Node Antibodies  >23 publications with TLR1 and Lymph Node
 Embryonic Tissue Antibodies  >16 publications with TLR1 and Embryonic Tissue
 Thymus Antibodies  >7 publications with TLR1 and Thymus
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions