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anti-TLR13 antibody :: Rabbit anti-Mouse, Rat TLR13 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS5400086
Unit / Price
0.1 mg Affinity-Purified  /  $390 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TLR13, Polyclonal Antibody

★Popular Item★
 Also Known As   

TLR13 Antibody

 Product Synonym Names    Toll like receptor 13 antibody
 Product Gene Name   

anti-TLR13 antibody

[Similar Products]
 Matching Pairs    Antibody: TLR13 (MBS5400086)
Positive Control: TLR13 (MBS543321)
 Antibody/Peptide Pairs    TLR13 peptide (MBS544577) is used for blocking the activity of TLR13 antibody (MBS5400086)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q6R5N8
 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Mouse, Rat
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 Form/Format    Affinity Purified
 Concentration    0.68 ug/ul in antibody stabilization buffer (lot specific)
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 Immunogen    Synthetic peptide taken within amino acid region 400-480 of mouse TLR13 protein.
 Molecular Function    protein homodimerization activity, rRNA binding
 Subcellular Location    endosome membrane, Single-pass type I membrane protein
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 Preparation and Storage    -20 degree C for long term storage
 Other Notes    Small volumes of anti-TLR13 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-TLR13 antibody

   Affinity Purified Toll-like receptor 13 Antibody
Component of innate and adaptive immunity that recognizes and binds 23S rRNA from bacteria. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
 Product Categories/Family for anti-TLR13 antibody    Primary Antibodies; Immunology; Innate Immunity; Macrophage / Inflammation; TLR13 Antibody
 Applications Tested/Suitable for anti-TLR13 antibody   

ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)

 Application Notes for anti-TLR13 antibody    Dot Blot: 1:10,000
ELISA: 1:10,000
Immunoprecipitation: 1:200
Western Blot: 1:500
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 Immunohistochemistry (IHC) of anti-TLR13 antibody    anti-TLR13 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-TLR13 antibody    anti-TLR13 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for TLR13. It may not necessarily be applicable to this product.
 NCBI GI #    109734930
 NCBI GeneID    279572
 NCBI Accession #    AAI17914.1 [Other Products]
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 UniProt Primary Accession #    Q6R5N8 [Other Products]
 UniProt Secondary Accession #    Q148Y7; Q3TDS2 [Other Products]
 UniProt Related Accession #    Q6R5N8 [Other Products]
 Molecular Weight    114,443 Da
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 NCBI Official Full Name    Toll-like receptor 13
 NCBI Official Synonym Full Names    toll-like receptor 13
 NCBI Official Symbol    Tlr13 [Similar Products]
 NCBI Official Synonym Symbols   
Gm713; AI666735
[Similar Products]
 NCBI Protein Information    toll-like receptor 13
 UniProt Protein Name    Toll-like receptor 13
 Protein Family    Toll-like receptor
 UniProt Gene Name    Tlr13 [Similar Products]
 UniProt Entry Name    TLR13_MOUSE
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 UniProt Comments for TLR13    TLR13: Component of innate and adaptive immunity that recognizes and binds 23S rRNA from bacteria. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Specifically binds the 5'-CGGAAAGACC-3' sequence on bacterial 23S rRNA, a sequence also bound by MLS group antibiotics (including erythromycin). May also recognize vesicular stomatitis virus; however, these data require additional evidences. Belongs to the Toll-like receptor family.

Protein type: Membrane protein, integral; Receptor, misc.

Cellular Component: cytoplasm; endosome; integral to membrane; membrane

Molecular Function: double-stranded RNA binding; protein binding; protein homodimerization activity; RNA binding; rRNA binding

Biological Process: immune system process; inflammatory response; innate immune response; MyD88-dependent toll-like receptor signaling pathway; regulation of MAPKKK cascade; response to virus; signal transduction; toll-like receptor 13 signaling pathway
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 Research Articles on TLR13    1. S. pyogenes is initially recognized in a phagocytosis-independent manner by TLR2 and subsequently by TLR13 upon internalization.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-TLR13 antibodyOrgans/Tissues associated with anti-TLR13 antibody
 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >3 publications with TLR13 and Disease Models, Animal
 Necrosis Antibodies  >3 publications with TLR13 and Necrosis
 Inflammation Antibodies  >2 publications with TLR13 and Inflammation
 Pneumonia Antibodies  >1 publications with TLR13 and Pneumonia
 Lung Diseases Antibodies  >1 publications with TLR13 and Lung Diseases
 Vascular Diseases Antibodies  >1 publications with TLR13 and Vascular Diseases
 Weight Loss Antibodies  >1 publications with TLR13 and Weight Loss
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >3 publications with TLR13 and Kidney
 Bone Antibodies  >2 publications with TLR13 and Bone
 Embryonic Tissue Antibodies  >1 publications with TLR13 and Embryonic Tissue
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