Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow TLR9 rightarrow Polyclonal TLR9  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • PKR1 ELISA Kit
 • RELA Antibody
 • Fibroblast Growth Factor 23 (FGF23) ELISA Kit
 • Interferon omega, IFN-omega ELISA Kit
 • CD49b Antibody
 • Collagen Type VII (COL7) ELISA Kit
 • CD28 Antibody
 • Myelin Basic Protein (MBP) ELISA Kit
 • Gastric Inhibitory Polypeptide (GIP) ELISA Kit
 • Encephalitis, St. Louis Antibody
 • Type II Iodothyronine Deiodinase (DIO2) ELISA Kit
 • Pyridinoline crosslinks (PYD) ELISA Kit
 • Hepatitis E Virus (HEV) ORF3 antigen (a.a. 92-123) Recombina... Recombinant Protein
 • cytochrome P450, family 4, subfamily B, polypeptide 1 (CYP4... Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-TLR9 antibody :: Rabbit anti-Human TLR9 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7049300
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TLR9, Polyclonal Antibody

★Popular Item★
 Also Known As   

TLR9 Antibody

 Product Synonym Names    Toll-like receptor 9; CD289; TLR9; UNQ5798/PRO19605
 Product Gene Name   

anti-TLR9 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    AF259262 mRNA
 3D Structure    ModBase 3D Structure for Q9NR96
Section Bar
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
Section Bar
 Purity/Purification    >95%, Protein G purified
 Form/Format    Liquid
Section Bar
 Immunogen    Recombinant Human Toll-like receptor 9 protein (425-563AA)
 Preservative    0.03% Proclin 300
 Constituents    50% Glycerol, 0.01M PBS, PH 7.4
 Conjugation    Non-conjugated
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-13215 / sc-13218 / sc-16247 / sc-25468
Section Bar
 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-TLR9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for anti-TLR9 antibody

   Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Controls lymphocyte response to Helicobacter infection.
 Applications Tested/Suitable for anti-TLR9 antibody   

ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)

 Application Notes for anti-TLR9 antibody    IHC: 1: 20-1: 200
IF: 1: 50-1: 200
Section Bar
 Immunohistochemistry (IHC) of anti-TLR9 antibody    Immunohistochemistry of paraffin-embedded human colon cancer using MBS7049300 at dilution of 1:100
anti-TLR9 antibody Immunohistochemistry (IHC) (IHC) image
Section Bar
 Immunofluorescence (IF) of anti-TLR9 antibody    Immunofluorescent analysis of HepG2 cells using MBS7049300 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-TLR9 antibody Immunofluorescence (IF) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for TLR9. It may not necessarily be applicable to this product.
 NCBI GI #    8394456
 NCBI GeneID    54106
 NCBI Accession #    NP_059138.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_017442.3 [Other Products]
Section Bar
 UniProt Primary Accession #    Q9NR96 [Other Products]
 UniProt Secondary Accession #    Q6UVZ2; Q9HD68; Q9HD69; Q9HD70; Q9NYC2; Q9NYC3; B3Y661; D1CS56 [Other Products]
 UniProt Related Accession #    Q9NR96 [Other Products]
 Molecular Weight    114,237 Da
Table BarTOPTable Bar
 NCBI Official Full Name    toll-like receptor 9
 NCBI Official Synonym Full Names    toll like receptor 9
 NCBI Official Symbol    TLR9 [Similar Products]
 NCBI Official Synonym Symbols   
CD289
[Similar Products]
 NCBI Protein Information    toll-like receptor 9
 UniProt Protein Name    Toll-like receptor 9
 UniProt Synonym Protein Names   
CD_antigen: CD289
 Protein Family    Toll-like receptor
 UniProt Gene Name    TLR9 [Similar Products]
 UniProt Entry Name    TLR9_HUMAN
Section Bar
 NCBI Summary for TLR9    The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for TLR9    TLR9: Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Controls lymphocyte response to Helicobacter infection. Interacts with MYD88 via their respective TIR domains. Interacts (via transmembrane domain) with UNC93B1. Interacts with CD300LH; the interaction may promote full activation of TLR9-triggered innate responses. Interacts with BTK. Interacts with CNPY3 and HSP90B1; this interaction is required for proper folding in the endoplasmic reticulum. Highly expressed in spleen, lymph node, tonsil and peripheral blood leukocytes, especially in plasmacytoid pre- dendritic cells. Levels are much lower in monocytes and CD11c+ immature dendritic cells. Also detected in lung and liver. Belongs to the Toll-like receptor family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: apical plasma membrane; basolateral plasma membrane; cytoplasm; endoplasmic reticulum; endoplasmic reticulum membrane; endosome; endosome membrane; Golgi membrane; lysosome; plasma membrane

Molecular Function: 1-phosphatidylinositol-3-kinase activity; interleukin-1 receptor binding; siRNA binding

Biological Process: activation of NF-kappaB transcription factor; axonogenesis; defense response to Gram-negative bacterium; I-kappaB phosphorylation; inhibition of NF-kappaB transcription factor; innate immune response; maintenance of gastrointestinal epithelium; negative regulation of interleukin-6 production; negative regulation of interleukin-8 production; negative regulation of toll-like receptor signaling pathway; positive regulation of chemokine production; positive regulation of granulocyte macrophage colony-stimulating factor production; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of inflammatory response; positive regulation of interferon-alpha biosynthetic process; positive regulation of interferon-beta biosynthetic process; positive regulation of interferon-beta production; positive regulation of interferon-gamma biosynthetic process; positive regulation of interleukin-10 production; positive regulation of interleukin-12 production; positive regulation of interleukin-18 production; positive regulation of interleukin-6 production; positive regulation of interleukin-8 production; positive regulation of JNK activity; positive regulation of JNK cascade; positive regulation of NF-kappaB import into nucleus; positive regulation of nitric-oxide synthase biosynthetic process; positive regulation of toll-like receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; positive regulation of tumor necrosis factor production; response to molecule of bacterial origin; toll-like receptor 9 signaling pathway; toll-like receptor signaling pathway; tumor necrosis factor production
Table BarTOPTable Bar
 Research Articles on TLR9    1. de novo expressed TLR9 may utilize endogenous mtDNA as the ligand to facilitate podocyte apoptosis, a novel mechanism underlying podocyte injury in glomerular diseases.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-TLR9 antibodyPathways associated with anti-TLR9 antibody
 Reference Product  PubMed Publications
 MYD88 antibody  >537 publications with TLR9 and MYD88
 CD40 antibody  >181 publications with TLR9 and CD40
 FOXP3 antibody  >60 publications with TLR9 and FOXP3
 TRAF6 antibody  >47 publications with TLR9 and TRAF6
 SYK antibody  >27 publications with TLR9 and SYK
 CCR7 antibody  >25 publications with TLR9 and CCR7
 CAMP antibody  >14 publications with TLR9 and CAMP
 IRF8 antibody  >10 publications with TLR9 and IRF8
 CNPY3 antibody  >1 publications with TLR9 and CNPY3
 Products by Pathway  Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 IGF1R Signaling Cascade Pathway antibodies  IGF1R Signaling Cascade Pathway Diagram
 IRS-mediated Signalling Pathway antibodies  IRS-mediated Signalling Pathway Diagram
 IRS-related Events Triggered By IGF1R Pathway antibodies  IRS-related Events Triggered By IGF1R Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
Diseases associated with anti-TLR9 antibodyOrgans/Tissues associated with anti-TLR9 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >821 publications with TLR9 and Inflammation
 Necrosis Antibodies  >517 publications with TLR9 and Necrosis
 Disease Models, Animal Antibodies  >339 publications with TLR9 and Disease Models, Animal
 Nervous System Diseases Antibodies  >161 publications with TLR9 and Nervous System Diseases
 Kidney Diseases Antibodies  >96 publications with TLR9 and Kidney Diseases
 Brain Diseases Antibodies  >92 publications with TLR9 and Brain Diseases
 Neoplasms, Experimental Antibodies  >77 publications with TLR9 and Neoplasms, Experimental
 Fibrosis Antibodies  >57 publications with TLR9 and Fibrosis
 Lung Neoplasms Antibodies  >49 publications with TLR9 and Lung Neoplasms
 Heart Diseases Antibodies  >46 publications with TLR9 and Heart Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1799 publications with TLR9 and Blood
 Lymph Node Antibodies  >142 publications with TLR9 and Lymph Node
 Lymph Antibodies  >128 publications with TLR9 and Lymph
 Thymus Antibodies  >23 publications with TLR9 and Thymus
 Tonsil Antibodies  >18 publications with TLR9 and Tonsil
 Trachea Antibodies  >8 publications with TLR9 and Trachea
 Thyroid Antibodies  >5 publications with TLR9 and Thyroid
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions