NP_003954.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
transmembrane 4 L6 family member 5
NCBI Official Synonym Full Names
transmembrane 4 L six family member 5
NCBI Protein Information
transmembrane 4 L6 family member 5
UniProt Protein Name
Transmembrane 4 L6 family member 5
UniProt Synonym Protein Names
Tetraspan transmembrane protein L6H
UniProt Entry Name
T4S5_HUMAN
NCBI Summary for TM4SF5
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is highly similar in sequence and structure to transmembrane 4 superfamily member 1. It may play a role in cell proliferation, and overexpression of this protein may be associated with the uncontrolled growth of tumour cells. [provided by RefSeq, Jul 2008]
UniProt Comments for TM4SF5
TM4SF5: a multi-pass membrane protein. Member of the transmembrane 4 superfamily, also known as the tetraspanin family. These proteins apparently mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is highly similar in sequence and structure to transmembrane 4 superfamily member 1. It may play a role in cell proliferation, and overexpression of this protein may be associated with the uncontrolled growth of tumour cells. and RefSeq
Protein type: Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 17p13.3
Cellular Component: integral to plasma membrane
Research Articles on TM4SF5
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Products associated with anti-TM4SF5 antibody
Diseases associated with anti-TM4SF5 antibody
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