NP_061180.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
28,081 Da
NCBI Official Full Name
type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase
NCBI Official Synonym Full Names
transmembrane protein 55A
NCBI Protein Information
type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase
UniProt Protein Name
Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase
UniProt Synonym Protein Names
PtdIns-4,5-P2 4-Ptase II; Transmembrane protein 55A
UniProt Synonym Gene Names
UniProt Entry Name
TM55A_HUMAN
NCBI Summary for TMEM55A
TMEM55A catalyzes the degradation of phosphatidylinositol 4,5-bisphosphate (PtdIns-4,5-P2) by removing the 4-phosphate (Ungewickell et al., 2005 [PubMed 16365287]).[supplied by OMIM, Mar 2008]
UniProt Comments for TMEM55A
TMEM55A: Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 4,5-bisphosphate. Does not hydrolyze phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-bisphosphate, inositol 3,5-bisphosphate, inositol 3,4- bisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4-monophosphate and phosphatidylinositol 3- monophosphate.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; EC 3.1.3.78; Phosphatase, lipid
Chromosomal Location of Human Ortholog: 8q21.3
Cellular Component: integral to membrane; late endosome membrane; lysosomal membrane
Biological Process: phosphoinositide dephosphorylation
Research Articles on TMEM55A
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Pathways associated with anti-TMEM55A antibody
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