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anti-TNFAIP8 antibody :: Rabbit anti-Human TNFAIP8 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7044940
Unit / Price
0.05 mL  /  $120 +1 FREE 8GB USB
0.1 mL  /  $160 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TNFAIP8, Polyclonal Antibody

★Popular Item★
 Also Known As   

TNFAIP8 Antibody

 Product Synonym Names    Tumor necrosis factor alpha-induced protein 8; TNF alpha-induced protein 8; Head and neck tumor and metastasis-related protein; MDC-3.13; NF-kappa-B-inducible DED-containing protein; NDED; SCC-S2; TNF-induced protein GG2-1; TNFAIP8
 Product Gene Name   

anti-TNFAIP8 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    612111
 3D Structure    ModBase 3D Structure for O95379
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Antigen Affinity Purified
 Form/Format    Liquid
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 Species    Human
 Immunogen    Recombinant human Tumor necrosis factor alpha-induced protein 8 protein (1-198AA)
 Conjugate    Non-conjugated
 Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-82054
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-TNFAIP8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-TNFAIP8 antibody

   Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.
 Applications Tested/Suitable for anti-TNFAIP8 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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 Western Blot (WB) of anti-TNFAIP8 antibody    Western blot
All lanes:  TNFAIP8antibody at 2.32ug/ml
Lane 1 : A431 whole cell lysate
Lane 2 : PC-3 whole cell lysate
Secondary
Goat polyclonal to Rabbit IgG at 1/10000 dilution
Predicted band size: 24,23,22,25 kDa
Observed band size: 23 kDa

anti-TNFAIP8 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-TNFAIP8 antibody    Immunohistochemistry of paraffin-embedded human colon cancer using MBS7044940 at dilution 1:100
anti-TNFAIP8 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-TNFAIP8 antibody    Immunohistochemistry of paraffin-embedded human breast cancer using MBS7044940 at dilution 1:100
anti-TNFAIP8 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for TNFAIP8. It may not necessarily be applicable to this product.
 NCBI GI #    117676370
 NCBI GeneID    25816
 NCBI Accession #    NP_001071122.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001077654.2 [Other Products]
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 UniProt Primary Accession #    O95379 [Other Products]
 UniProt Secondary Accession #    Q9P1Q1; Q9UER5; Q9UP47; B3KMH1; B3KMI2; B7Z713 [Other Products]
 UniProt Related Accession #    O95379 [Other Products]
 Molecular Weight    24,385 Da
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 NCBI Official Full Name    tumor necrosis factor alpha-induced protein 8 isoform b
 NCBI Official Synonym Full Names    TNF alpha induced protein 8
 NCBI Official Symbol    TNFAIP8 [Similar Products]
 NCBI Official Synonym Symbols   
NDED; GG2-1; SCCS2; SCC-S2; MDC-3.13
[Similar Products]
 NCBI Protein Information    tumor necrosis factor alpha-induced protein 8
 UniProt Protein Name    Tumor necrosis factor alpha-induced protein 8
 UniProt Synonym Protein Names   
Head and neck tumor and metastasis-related protein; MDC-3.13; NF-kappa-B-inducible DED-containing protein; NDED; SCC-S2; TNF-induced protein GG2-1
 Protein Family    Tumor necrosis factor alpha-induced protein
 UniProt Gene Name    TNFAIP8 [Similar Products]
 UniProt Synonym Gene Names    TNF alpha-induced protein 8; NDED [Similar Products]
 UniProt Entry Name    TFIP8_HUMAN
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 UniProt Comments for TNFAIP8    TNFAIP8: Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation. Belongs to the TNFAIP8 family. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 5q23.1

Cellular Component: cytoplasm

Molecular Function: caspase inhibitor activity; protein binding

Biological Process: negative regulation of apoptosis
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 Research Articles on TNFAIP8    1. Expression of TNFAIP8 is up-regulated in human gastric cancer and regulates cell proliferation, invasion and migration.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-TNFAIP8 antibodyOrgans/Tissues associated with anti-TNFAIP8 antibody
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >33 publications with TNFAIP8 and Necrosis
 Inflammation Antibodies  >11 publications with TNFAIP8 and Inflammation
 Neoplasm Metastasis Antibodies  >7 publications with TNFAIP8 and Neoplasm Metastasis
 Disease Models, Animal Antibodies  >5 publications with TNFAIP8 and Disease Models, Animal
 Adenocarcinoma Antibodies  >4 publications with TNFAIP8 and Adenocarcinoma
 Neoplasms, Experimental Antibodies  >2 publications with TNFAIP8 and Neoplasms, Experimental
 Lung Neoplasms Antibodies  >2 publications with TNFAIP8 and Lung Neoplasms
 Carcinoma, Hepatocellular Antibodies  >2 publications with TNFAIP8 and Carcinoma, Hepatocellular
 Weight Loss Antibodies  >2 publications with TNFAIP8 and Weight Loss
 Cell Transformation, Neoplastic Antibodies  >2 publications with TNFAIP8 and Cell Transformation, Neoplastic
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >2 publications with TNFAIP8 and Lung
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