NP_003811.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 30 kDa Predicted: 31 kDa
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 14 isoform 1
NCBI Official Synonym Full Names
TNF receptor superfamily member 14
NCBI Official Synonym Symbols
TR2; ATAR; HVEA; HVEM; CD270; LIGHTR [Similar Products]
NCBI Protein Information
tumor necrosis factor receptor superfamily member 14
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 14
UniProt Synonym Protein Names
Herpes virus entry mediator A; Herpesvirus entry mediator A; HveA; Tumor necrosis factor receptor-like 2; TR2; CD_antigen: CD270
UniProt Synonym Gene Names
NCBI Summary for TNFRSF14
This gene encodes a member of the TNF (tumor necrosis factor) receptor superfamily. The encoded protein functions in signal transduction pathways that activate inflammatory and inhibitory T-cell immune response. It binds herpes simplex virus (HSV) viral envelope glycoprotein D (gD), mediating its entry into cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
UniProt Comments for TNFRSF14
Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells.
Research Articles on TNFRSF14
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Disclaimer
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Products associated with anti-TNFRSF14 antibody
Pathways associated with anti-TNFRSF14 antibody
Diseases associated with anti-TNFRSF14 antibody
Organs/Tissues associated with anti-TNFRSF14 antibody
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