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anti-TNNC2 antibody :: Rabbit anti-Human, Mouse TNNC2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS1496004
Unit / Price
0.05 mL  /  $120 +1 FREE 8GB USB
0.1 mL  /  $160 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TNNC2, Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-human TNNC2 polyclonal Antibody

 Product Synonym Names    TNNC2
 Product Gene Name   

anti-TNNC2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    191039
 3D Structure    ModBase 3D Structure for P02585
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Purity/Purification    Antigen Affinity Purified
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 Storage Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
 Conjugate    Non-conjugated
 Immunogen    Recombinant human Troponin C, skeletal muscle protein (1-160aa)
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-30481 / sc-8117 / sc-30480
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-TNNC2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-TNNC2 antibody

   Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.
 Applications Tested/Suitable for anti-TNNC2 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-TNNC2 antibody    Recommended dilution: WB:1:500-2000
IHC:1:20-1:200
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 Western Blot (WB) of anti-TNNC2 antibody    All lanes: TNNC2 antibody at 10ug/ml+mouse skeletal muscleSecondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 18kDa
Observed band size: 18kDa

anti-TNNC2 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-TNNC2 antibody    Immunohistochemistry of paraffin-embedded human rectum using MBS1496004 at dilution 1:100
anti-TNNC2 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for TNNC2. It may not necessarily be applicable to this product.
 NCBI GI #    4507617
 NCBI GeneID    7125
 NCBI Accession #    NP_003270.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_003279.2 [Other Products]
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 UniProt Primary Accession #    P02585 [Other Products]
 UniProt Secondary Accession #    Q6FH92 [Other Products]
 UniProt Related Accession #    P02585 [Other Products]
 Molecular Weight    18,122 Da
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 NCBI Official Full Name    troponin C, skeletal muscle
 NCBI Official Synonym Full Names    troponin C type 2 (fast)
 NCBI Official Symbol    TNNC2 [Similar Products]
 NCBI Protein Information    troponin C, skeletal muscle
 UniProt Protein Name    Troponin C, skeletal muscle
 Protein Family    Troponin
 UniProt Gene Name    TNNC2 [Similar Products]
 UniProt Entry Name    TNNC2_HUMAN
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 NCBI Summary for TNNC2    Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn-C subunit. [provided by RefSeq, Jul 2008]
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 UniProt Comments for TNNC2    TNNC2: Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. Belongs to the troponin C family.

Protein type: Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 20q12-q13.11

Cellular Component: cytosol; troponin complex

Molecular Function: actin binding; calcium ion binding; protein binding

Biological Process: muscle filament sliding; regulation of muscle contraction; skeletal muscle contraction
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 Research Articles on TNNC2    1. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-TNNC2 antibodyPathways associated with anti-TNNC2 antibody
 Reference Product  PubMed Publications
 TNNI2 antibody  >3 publications with TNNC2 and TNNI2
 TNNT3 antibody  >3 publications with TNNC2 and TNNT3
 MYH8 antibody  >2 publications with TNNC2 and MYH8
 MYL1 antibody  >1 publications with TNNC2 and MYL1
 MYH3 antibody  >1 publications with TNNC2 and MYH3
 TNNI1 antibody  >1 publications with TNNC2 and TNNI1
 Products by Pathway  Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Muscle Contraction Pathway antibodies  Muscle Contraction Pathway Diagram
 Striated Muscle Contraction Pathway antibodies  Striated Muscle Contraction Pathway Diagram
 Striated Muscle Contraction Pathway antibodies  Striated Muscle Contraction Pathway Diagram
Diseases associated with anti-TNNC2 antibodyOrgans/Tissues associated with anti-TNNC2 antibody
 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >2 publications with TNNC2 and Congenital Abnormalities
 Death Antibodies  >1 publications with TNNC2 and Death
 Hypertension Antibodies  >1 publications with TNNC2 and Hypertension
 Abnormalities, Multiple Antibodies  >1 publications with TNNC2 and Abnormalities, Multiple
 Nervous System Diseases Antibodies  >1 publications with TNNC2 and Nervous System Diseases
 Fetal Death Antibodies  >1 publications with TNNC2 and Fetal Death
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >10 publications with TNNC2 and Muscle
 Heart Antibodies  >3 publications with TNNC2 and Heart
 Lung Antibodies  >2 publications with TNNC2 and Lung
 Nerve Antibodies  >1 publications with TNNC2 and Nerve
 Vascular Antibodies  >1 publications with TNNC2 and Vascular
 Placenta Antibodies  >1 publications with TNNC2 and Placenta
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