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anti-TNS1 antibody :: Goat TNS1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS6009523 anti-TNS1 antibody
Unit / Price
0.1 mg  /  $560 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TNS1, Polyclonal Antibody

★Popular Item★
 Also Known As   

TNS1 (Tensin-1, TNS)

 Product Synonym Names    Anti -TNS1 (Tensin-1, TNS)
 Product Gene Name   

anti-TNS1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 2; NC_000002.11 (218664512..218808796, complement). Location: 2q35-q36
 OMIM    600076
 3D Structure    ModBase 3D Structure for Q9HBL0
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Goat
 Species Reactivity    Bovine, Canine, Human, Mouse, Rat
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 Specificity    Recognizes Human TNS1.
 Purity/Purification    Affinity Purified
Purified by immunoaffinity chromatography.
 Form/Format    Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
 Concentration    0.5mg/ml (lot specific)
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 Immunogen    Synthetic peptide corresponding to C-VSKVMLNAGQKR, from TNS1, at C-terminal (NP_072174.3).
Species sequence homology: Bovine, canine, mouse and rat.
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 Preparation and Storage    May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
 Other Notes    Small volumes of anti-TNS1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-TNS1 antibody

   Tensin 1 may be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton.
 Product Categories/Family for anti-TNS1 antibody    Antibodies; Abs to Signal Transduction
 Applications Tested/Suitable for anti-TNS1 antibody   

ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-TNS1 antibody    Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Dilution: ELISA: 1:2000
Western Blot: 1ug/ml
Immunohistochemistry (Paraffin): 4-6ug/ml
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NCBI/Uniprot data below describe general gene information for TNS1. It may not necessarily be applicable to this product.
 NCBI GI #    66529407
 NCBI GeneID    7145
 NCBI Accession #    NP_072174.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_022648.4 [Other Products]
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 UniProt Primary Accession #    Q9HBL0 [Other Products]
 UniProt Secondary Accession #    Q4ZG71 [Other Products]
 UniProt Related Accession #    Q9HBL0 [Other Products]
 Molecular Weight    185,701 Da [Similar Products]
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 NCBI Official Full Name    tensin-1
 NCBI Official Synonym Full Names    tensin 1
 NCBI Official Symbol    TNS1 [Similar Products]
 NCBI Official Synonym Symbols   
TNS; MXRA6; MST091; MST122; MST127; MSTP091; MSTP122; MSTP127
[Similar Products]
 NCBI Protein Information    tensin-1; matrix-remodelling associated 6; Matrix-remodelling-associated protein 6
 UniProt Protein Name    Tensin-1
 Protein Family    Tensin
 UniProt Gene Name    TNS1 [Similar Products]
 UniProt Synonym Gene Names    TNS [Similar Products]
 UniProt Entry Name    TENS1_HUMAN
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 NCBI Summary for TNS1    The protein encoded by this gene localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. A second transcript from this gene has been described, but its full length nature has not been determined. [provided by RefSeq, Jul 2008]
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 UniProt Comments for TNS1    tensin 1: May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton.

Protein type: Adaptor/scaffold; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2q35-q36

Cellular Component: cell surface; focal adhesion; cytoskeleton; cytoplasm

Molecular Function: protein binding; actin binding

Biological Process: cell-substrate junction assembly
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 Research Articles on TNS1    1. TNS1 polymorphism associated with COPD risk and lung function decline
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-TNS1 antibodyDiseases associated with anti-TNS1 antibody
 Products by Pathway  Pathway Diagram
 Integrin-mediated Cell Adhesion Pathway antibodies  Integrin-mediated Cell Adhesion Pathway Diagram
 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >1 publications with TNS1 and Brain Diseases
 Neoplasms Antibodies  >1 publications with TNS1 and Neoplasms
 Breast Neoplasms Antibodies  >1 publications with TNS1 and Breast Neoplasms
Organs/Tissues associated with anti-TNS1 antibody
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >5 publications with TNS1 and Lung
 Heart Antibodies  >2 publications with TNS1 and Heart
 Blood Antibodies  >1 publications with TNS1 and Blood
 Kidney Antibodies  >1 publications with TNS1 and Kidney
 Intestine Antibodies  >1 publications with TNS1 and Intestine
 Brain Antibodies  >1 publications with TNS1 and Brain
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