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anti-TPH1 antibody :: Rabbit anti-Human, Mouse TPH1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7049328
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TPH1, Polyclonal Antibody

★Popular Item★
 Also Known As   

TPH1 Antibody

 Product Synonym Names    Tryptophan 5-hydroxylase 1; Tryptophan 5-monooxygenase 1; TPH1; TPH; TPRH; TRPH
 Product Gene Name   

anti-TPH1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    X52836 mRNA
 3D Structure    ModBase 3D Structure for P17752
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Purity/Purification    >95%, Protein G purified
 Form/Format    Liquid
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 Immunogen    Recombinant Human Tryptophan 5-hydroxylase 1 protein (257-405AA)
 Preservative    0.03% Proclin 300
 Constituents    50% Glycerol, 0.01M PBS, PH 7.4
 Conjugation    Non-conjugated
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-15114 / sc-15116 / sc-30079
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-TPH1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-TPH1 antibody

   cytosol, indolalkylamine biosynthetic process
 Applications Tested/Suitable for anti-TPH1 antibody   

ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)

 Application Notes for anti-TPH1 antibody    WB: 1: 500-1: 5000
IF: 1: 50-1: 200
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 Western Blot (WB) of anti-TPH1 antibody    Western Blot
Positive WB detected in:Mouse heart tissue,Mouse skeletal muscle tissue
All lanes: Tph1 antibody at 2.5ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 51,54 kDa
Observed band size: 51 kDa

anti-TPH1 antibody Western Blot (WB) (WB) image
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 Immunofluorescence (IF) of anti-TPH1 antibody    Immunofluorescent analysis of U251 cells using MBS7049328 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-TPH1 antibody Immunofluorescence (IF) image
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NCBI/Uniprot data below describe general gene information for TPH1. It may not necessarily be applicable to this product.
 NCBI GI #    4759248
 NCBI GeneID    7166
 NCBI Accession #    NP_004170.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_004179.2 [Other Products]
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 UniProt Primary Accession #    P17752 [Other Products]
 UniProt Secondary Accession #    O95188; O95189; Q16736; Q3KPG8; D3DQX6 [Other Products]
 UniProt Related Accession #    P17752 [Other Products]
 Molecular Weight    53,394 Da
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 NCBI Official Full Name    tryptophan 5-hydroxylase 1
 NCBI Official Synonym Full Names    tryptophan hydroxylase 1
 NCBI Official Symbol    TPH1 [Similar Products]
 NCBI Official Synonym Symbols   
TPRH; TRPH
[Similar Products]
 NCBI Protein Information    tryptophan 5-hydroxylase 1
 UniProt Protein Name    Tryptophan 5-hydroxylase 1
 UniProt Synonym Protein Names   
Tryptophan 5-monooxygenase 1
 Protein Family    Tryptophan 5-hydroxylase
 UniProt Gene Name    TPH1 [Similar Products]
 UniProt Synonym Gene Names    TPH; TPRH; TRPH [Similar Products]
 UniProt Entry Name    TPH1_HUMAN
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 NCBI Summary for TPH1    This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.[provided by RefSeq, Apr 2009]
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 Research Articles on TPH1    1. Polymorphisms in the TPH1 gene may be represented by diminished activity in lateral areas of the PFC underlying response inhibition.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-TPH1 antibodyPathways associated with anti-TPH1 antibody
 Reference Product  PubMed Publications
 TPH2 antibody  >149 publications with TPH1 and TPH2
 SLC6A4 antibody  >62 publications with TPH1 and SLC6A4
 LRP5 antibody  >11 publications with TPH1 and LRP5
 DDC antibody  >11 publications with TPH1 and DDC
 HTR7 antibody  >3 publications with TPH1 and HTR7
 IDO1 antibody  >2 publications with TPH1 and IDO1
 YWHAZ antibody  >1 publications with TPH1 and YWHAZ
 IDO2 antibody  >1 publications with TPH1 and IDO2
 Products by Pathway  Pathway Diagram
 Amine-derived Hormones Pathway antibodies  Amine-derived Hormones Pathway Diagram
 Amino Acid Metabolism Pathway antibodies  Amino Acid Metabolism Pathway Diagram
 Biogenic Amine Synthesis Pathway antibodies  Biogenic Amine Synthesis Pathway Diagram
 Circadian Rythm Related Genes Pathway antibodies  Circadian Rythm Related Genes Pathway Diagram
 Melatonin Biosynthesis, Tryptophan => Serotonin => Melatonin Pathway antibodies  Melatonin Biosynthesis, Tryptophan => Serotonin => Melatonin Pathway Diagram
 Melatonin Biosynthesis, Tryptophan => Serotonin => Melatonin Pathway antibodies  Melatonin Biosynthesis, Tryptophan => Serotonin => Melatonin Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram
 Serotonergic Synapse Pathway antibodies  Serotonergic Synapse Pathway Diagram
Diseases associated with anti-TPH1 antibodyOrgans/Tissues associated with anti-TPH1 antibody
 Disease Name  Pubmed Publications
 Depressive Disorder Antibodies  >44 publications with TPH1 and Depressive Disorder
 Inflammation Antibodies  >36 publications with TPH1 and Inflammation
 Schizophrenia Antibodies  >29 publications with TPH1 and Schizophrenia
 Disease Models, Animal Antibodies  >23 publications with TPH1 and Disease Models, Animal
 Nervous System Diseases Antibodies  >19 publications with TPH1 and Nervous System Diseases
 Hypertension Antibodies  >19 publications with TPH1 and Hypertension
 Hypertension, Pulmonary Antibodies  >19 publications with TPH1 and Hypertension, Pulmonary
 Immune System Diseases Antibodies  >13 publications with TPH1 and Immune System Diseases
 Necrosis Antibodies  >11 publications with TPH1 and Necrosis
 Liver Diseases Antibodies  >10 publications with TPH1 and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >130 publications with TPH1 and Brain
 Intestine Antibodies  >44 publications with TPH1 and Intestine
 Lung Antibodies  >19 publications with TPH1 and Lung
 Pituitary Gland Antibodies  >2 publications with TPH1 and Pituitary Gland
 Eye Antibodies  >2 publications with TPH1 and Eye
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