Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow TRPV5 rightarrow Polyclonal TRPV5  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Glycated hemoglobin A1c (GHbA1c) ELISA Kit
 • OLA1 Recombinant Protein
 • ACAT1 Antibody
 • ROS (pY2114) (ROS1) Antibody
 • Transforming Growth Factor Beta Induced (TGFbI) ELISA Kit
 • CG ELISA Kit
 • GALECTIN-1 (LGALS1) Recombinant Protein
 • PLA2G2D Antibody
 • Abeta1-42 ELISA Kit
 • SOX1 ELISA Kit
 • ATP-dependent RNA helicase DDX39A Antibody
 • Prostate Specific Membrane (PSMA) Recombinant Protein
 • SOCS3 ELISA Kit
 • Melanoma Associated ME20 (ME20M) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-TRPV5 antibody :: Goat TRPV5 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS420745
Western Blot (WB)
Unit / Price
0.1 mg  /  $300 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TRPV5, Polyclonal Antibody

 Also Known As   

Goat anti-TRPV5 Antibody

 Product Synonym Names    TRPV5; transient receptor potential cation channel, subfamily V, member 5; CAT2; ECAC1; OTRPC3; calcium transporter 2; epithelial calcium channel 1; osm-9-like TRP channel 3; TRPV5 antibody; transient receptor potential cation channel; subfamily V; member 5 antibody; CAT2 antibody; ECAC1 antibody; OTRPC3 antibody; calcium transporter 2 antibody; epithelial calcium channel 1 antibody; osm-9-like TRP channel 3 antibody
 Product Gene Name   

anti-TRPV5 antibody

[Similar Products]
 Matching Pairs    Unconjugated Antibody: TRPV5 (MBS420745)
Biotin Antibody: TRPV5 (MBS423682)
 Antibody/Peptide Pairs    TRPV5 peptide (MBS426896) is used for blocking the activity of TRPV5 antibody (MBS420745)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Immunogen Sequence    SHRGWEILRQ NT
 OMIM    606679
Section Bar
 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog, Pig, Cow
Section Bar
 Purity/Purification    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
 Form/Format    Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
 Concentration    100ug specific antibody in 200ul (lot specific)
Section Bar
 Immunogen    Peptide with sequence C-SHRGWEILRQNT, from the internal region of the protein sequence according to NP_062815.2.
 Epitope    Internal region
Section Bar
 Preparation and Storage    Aliquot and store at -20 degree C. Minimize freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-TRPV5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 Applications Tested/Suitable for anti-TRPV5 antibody   

Peptide ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

 Application Notes for anti-TRPV5 antibody    Peptide ELISA: Antibody detection limit dilution 1: 16000.
Western Blot: Approx 85kDa band observed in Human Pancreas lysates (calculated MW of 82.6kDa according to NP_062815.2). Recommended concentration: 1-3ug/ml.
Immunocytochemsitry/Immunofluorescence: This antibody has been successfully used in ICC/IF for human retinal pigment epithelium as described in the following paper: Kennedy et al, Mol Vis.2010 Apr 14;16: 665-75; PMID: 20405023.
Section Bar
 Western Blot (WB) of anti-TRPV5 antibody    (1ug/ml) staining of Human Pancreas lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
anti-TRPV5 antibody Western Blot (WB) (WB) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for TRPV5. It may not necessarily be applicable to this product.
 NCBI GI #    17505200
 NCBI GeneID    56302
 NCBI Accession #    NP_062815.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_019841.5 [Other Products]
Section Bar
 UniProt Secondary Accession #    Q8N4C1; Q8NDW5; Q8NDX7; Q8NDX8; Q96PM6; A4D2H7; E9PBZ6 [Other Products]
 UniProt Related Accession #    Q9NQA5 [Other Products]
 Molecular Weight    43,186 Da
Table BarTOPTable Bar
 NCBI Official Full Name    transient receptor potential cation channel subfamily V member 5
 NCBI Official Synonym Full Names    transient receptor potential cation channel subfamily V member 5
 NCBI Official Symbol    TRPV5 [Similar Products]
 NCBI Official Synonym Symbols   
CAT2; ECAC1; OTRPC3
[Similar Products]
 NCBI Protein Information    transient receptor potential cation channel subfamily V member 5
 UniProt Protein Name    Transient receptor potential cation channel subfamily V member 5
 UniProt Synonym Protein Names   
Calcium transport protein 2; CaT2; Epithelial calcium channel 1; ECaC; ECaC1; Osm-9-like TRP channel 3; OTRPC3
 Protein Family    Transient receptor potential cation channel subfamily
 UniProt Gene Name    TRPV5 [Similar Products]
 UniProt Synonym Gene Names    ECAC1; TrpV5; CaT2; ECaC; ECaC1; OTRPC3 [Similar Products]
 UniProt Entry Name    TRPV5_HUMAN
Section Bar
 NCBI Summary for TRPV5    This gene is a member of the transient receptor family and the TrpV subfamily. The calcium-selective channel encoded by this gene has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for TRPV5    TRPV5: Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine. The channel is activated by low internal calcium level and the current exhibits an inward rectification. A Ca(2+)- dependent feedback regulation includes fast channel inactivation and slow current decay. Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating. Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV5 sub-subfamily.

Protein type: Motility/polarity/chemotaxis; Membrane protein, multi-pass; Channel, cation; Membrane protein, integral

Chromosomal Location of Human Ortholog: 7q35

Cellular Component: apical plasma membrane; integral to plasma membrane; plasma membrane

Molecular Function: calcium channel activity; calmodulin binding; protein binding

Biological Process: calcium ion transport; protein tetramerization
Table BarTOPTable Bar
 Research Articles on TRPV5    1. Data found that a TRPV5 polymorphism (rs4236480) was observed to be associated with stone multiplicity of calcium nephrolithiasis, as the risk of stone multiplicity was higher in patients with the TT+CT genotype than in patients with the CC genotype
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-TRPV5 antibodyPathways associated with anti-TRPV5 antibody
 Reference Product  PubMed Publications
 PTH antibody  >24 publications with TRPV5 and PTH
 CALB1 antibody  >23 publications with TRPV5 and CALB1
 TRPM7 antibody  >15 publications with TRPV5 and TRPM7
 TRPM4 antibody  >12 publications with TRPV5 and TRPM4
 LGALS1 antibody  >6 publications with TRPV5 and LGALS1
 WNK3 antibody  >3 publications with TRPV5 and WNK3
 BSPRY antibody  >2 publications with TRPV5 and BSPRY
 RAB11A antibody  >2 publications with TRPV5 and RAB11A
 FKBP4 antibody  >1 publications with TRPV5 and FKBP4
 Products by Pathway  Pathway Diagram
 Endocrine And Other Factor-regulated Calcium Reabsorption Pathway antibodies  Endocrine And Other Factor-regulated Calcium Reabsorption Pathway Diagram
 Endocrine And Other Factor-regulated Calcium Reabsorption Pathway antibodies  Endocrine And Other Factor-regulated Calcium Reabsorption Pathway Diagram
 Ion Channel Transport Pathway antibodies  Ion Channel Transport Pathway Diagram
 Osteoclast Signaling Pathway antibodies  Osteoclast Signaling Pathway Diagram
 Stimuli-sensing Channels Pathway antibodies  Stimuli-sensing Channels Pathway Diagram
 TRP Channels Pathway antibodies  TRP Channels Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
Diseases associated with anti-TRPV5 antibodyOrgans/Tissues associated with anti-TRPV5 antibody
 Disease Name  Pubmed Publications
 Hypercalciuria Antibodies  >53 publications with TRPV5 and Hypercalciuria
 Kidney Diseases Antibodies  >42 publications with TRPV5 and Kidney Diseases
 Hypertension Antibodies  >19 publications with TRPV5 and Hypertension
 Osteoporosis Antibodies  >16 publications with TRPV5 and Osteoporosis
 Hypocalcemia Antibodies  >14 publications with TRPV5 and Hypocalcemia
 Cardiovascular Diseases Antibodies  >9 publications with TRPV5 and Cardiovascular Diseases
 Pain Antibodies  >7 publications with TRPV5 and Pain
 Insulin Resistance Antibodies  >6 publications with TRPV5 and Insulin Resistance
 Renal Insufficiency Antibodies  >5 publications with TRPV5 and Renal Insufficiency
 Fibrosis Antibodies  >4 publications with TRPV5 and Fibrosis
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >74 publications with TRPV5 and Blood
 Lung Antibodies  >5 publications with TRPV5 and Lung
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions