AAH24270.1
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
TSPY-like 2
NCBI Official Synonym Full Names
TSPY-like 2
NCBI Official Synonym Symbols
CDA1; CTCL; NP79; TSPX; CINAP; DENTT; SE204; HRIHFB2216 [Similar Products]
NCBI Protein Information
testis-specific Y-encoded-like protein 2; TSPY-like protein 2; CTCL tumor antigen se20-4; nuclear protein of 79 kDa; cell division autoantigen 1; CTCL-associated antigen se20-4; testis-specific protein Y encoded-like 2; CASK-interacting nucleosome assembly protein; cutaneous T-cell lymphoma-associated antigen se20-4; differentially expressed nucleolar TGF-beta1 target; cutaneous T-cell lymphoma-associated tumor antigen se20-4; differentially-expressed nucleolar TGF-beta1 target protein
UniProt Protein Name
Testis-specific Y-encoded-like protein 2
UniProt Synonym Protein Names
Cell division autoantigen 1; Cutaneous T-cell lymphoma-associated antigen se20-4; CTCL-associated antigen se20-4; Differentially-expressed nucleolar TGF-beta1 target protein; Nuclear protein of 79 kDa; NP79
UniProt Synonym Gene Names
CDA1; DENTT; TSPX; TSPY-like protein 2; CTCL-associated antigen se20-4; NP79 [Similar Products]
UniProt Entry Name
TSYL2_HUMAN
NCBI Summary for TSPYL2
This gene encodes a member of the testis-specific protein Y-encoded, TSPY-like/SET/nucleosome assembly protein-1 superfamily. The encoded protein is localized to the nucleolus where it functions in chromatin remodeling and as an inhibitor of cell-cycle progression. This protein may play a role in the suppression of tumor growth. [provided by RefSeq, Sep 2009]
UniProt Comments for TSPYL2
TSPYL2: Part of the CASK/TRB1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression. Belongs to the nucleosome assembly protein (NAP) family.
Protein type: DNA replication; Transcription regulation
Chromosomal Location of Human Ortholog: Xp11.2
Cellular Component: nucleoplasm; centrosome; cytoplasm; nucleolus; plasma membrane; nucleus
Molecular Function: rDNA binding
Biological Process: transcription, DNA-dependent; unfolded protein response; regulation of signal transduction; chromatin modification; cell cycle; negative regulation of cell cycle; nucleosome assembly; unfolded protein response, activation of signaling protein activity; cellular protein metabolic process; regulation of transcription, DNA-dependent; negative regulation of DNA replication; negative regulation of cell growth; regulation of protein kinase activity
Research Articles on TSPYL2
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Products associated with anti-TSPYL2 antibody
Pathways associated with anti-TSPYL2 antibody
Diseases associated with anti-TSPYL2 antibody
Organs/Tissues associated with anti-TSPYL2 antibody
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