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anti-TUBA4A antibody :: Rabbit anti-Human, Mouse TUBA4A Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7049539
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TUBA4A, Polyclonal Antibody

★Popular Item★
 Also Known As   

TUBA4A Antibody

 Product Synonym Names    Tubulin alpha-4A chain; Alpha-tubulin 1; Testis-specific alpha-tubulin; Tubulin H2-alpha; Tubulin alpha-1 chain; TUBA4A; TUBA1
 Product Gene Name   

anti-TUBA4A antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    X06956 Genomic DNA
 3D Structure    ModBase 3D Structure for P68366
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Purity/Purification    >95%, Protein G purified
 Form/Format    Liquid
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 Immunogen    Recombinant human Tubulin alpha-4A chain protein (20-183AA)
 Preservative    0.03% Proclin 300
 Constituents    50% Glycerol, 0.01M PBS, PH 7.4
 Conjugation    Non-conjugated
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-31779
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-TUBA4A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-TUBA4A antibody

   Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
 Applications Tested/Suitable for anti-TUBA4A antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

 Application Notes for anti-TUBA4A antibody    WB: 1: 1000-1: 5000
IHC: 1: 20-1: 200
IF: 1: 50-1: 200
IP: 1: 200-1: 2000
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 Western Blot (WB) of anti-TUBA4A antibody    Western Blot
Positive WB detected in:NIH/3T3 whole cell lysate,K562 whole cell lysate,Mouse brain tissue
All lanes: TUBA4A antibody at 3ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 50,49 kDa
Observed band size: 50,24 kDa

anti-TUBA4A antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-TUBA4A antibody    Immunohistochemistry of paraffin-embedded human colon cancer using MBS7049539 at dilution of 1:100
anti-TUBA4A antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-TUBA4A antibody    Immunohistochemistry of paraffin-embedded human gastric cancer using MBS7049539 at dilution of 1:100
anti-TUBA4A antibody Immunohistochemistry (IHC) (IHC) image
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 Immunofluorescence (IF) of anti-TUBA4A antibody    Immunofluorescent analysis of HepG2 cells using MBS7049539 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-TUBA4A antibody Immunofluorescence (IF) image
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 Immunoprecipitation (IP) of anti-TUBA4A antibody    Immunoprecipitating TUBA4A in K562 whole cell lysate
Lane 1: Rabbit monoclonal IgG(1ug)instead of MBS7049539 in K562 whole cell lysate. For western blotting, a HRP-conjugated light chain specific antibody was used as the Secondary antibody (1/50000)
Lane 2: MBS7049539(4ug)+ K562 whole cell lysate(500ug)
Lane 3: K562 whole cell lysate (20ug)

anti-TUBA4A antibody Immunoprecipitation (IP) (IP) image
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NCBI/Uniprot data below describe general gene information for TUBA4A. It may not necessarily be applicable to this product.
 NCBI GI #    514052659
 NCBI GeneID    7277
 NCBI Accession #    NP_001265481.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001278552.1 [Other Products]
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 UniProt Primary Accession #    P68366 [Other Products]
 UniProt Secondary Accession #    P05215; A8MUB1; B3KNQ6 [Other Products]
 UniProt Related Accession #    P68366 [Other Products]
 Molecular Weight    48,329 Da
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 NCBI Official Full Name    tubulin alpha-4A chain isoform 2
 NCBI Official Synonym Full Names    tubulin alpha 4a
 NCBI Official Symbol    TUBA4A [Similar Products]
 NCBI Official Synonym Symbols   
ALS22; TUBA1; H2-ALPHA
[Similar Products]
 NCBI Protein Information    tubulin alpha-4A chain
 UniProt Protein Name    Tubulin alpha-4A chain
 UniProt Synonym Protein Names   
Alpha-tubulin 1; Testis-specific alpha-tubulin; Tubulin H2-alpha; Tubulin alpha-1 chain
 Protein Family    Tubulin
 UniProt Gene Name    TUBA4A [Similar Products]
 UniProt Synonym Gene Names    TUBA1 [Similar Products]
 UniProt Entry Name    TBA4A_HUMAN
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 NCBI Summary for TUBA4A    Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene encodes an alpha tubulin that is a highly conserved homolog of a rat testis-specific alpha tubulin. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013]
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 UniProt Comments for TUBA4A    TUBA4A: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. Dimer of alpha and beta chains. Belongs to the tubulin family.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2q35

Cellular Component: cytosol; extracellular region; microtubule

Molecular Function: protein binding

Biological Process: G2/M transition of mitotic cell cycle; platelet degranulation

Disease: Amyotrophic Lateral Sclerosis 22 With Or Without Frontotemporal Dementia
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 Research Articles on TUBA4A    1. TUBA4A mutations are not associated with FTD.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-TUBA4A antibodyPathways associated with anti-TUBA4A antibody
 Reference Product  PubMed Publications
 TUBA1A antibody  >4 publications with TUBA4A and TUBA1A
 UBC antibody  >2 publications with TUBA4A and UBC
 TBCE antibody  >1 publications with TUBA4A and TBCE
 TUBB2A antibody  >1 publications with TUBA4A and TUBB2A
 Products by Pathway  Pathway Diagram
 AURKA Activation By TPX2 Pathway antibodies  AURKA Activation By TPX2 Pathway Diagram
 Anchoring Of The Basal Body To The Plasma Membrane Pathway antibodies  Anchoring Of The Basal Body To The Plasma Membrane Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Centrosome Maturation Pathway antibodies  Centrosome Maturation Pathway Diagram
 Chaperonin-mediated Protein Folding Pathway antibodies  Chaperonin-mediated Protein Folding Pathway Diagram
 Cilium Assembly Pathway antibodies  Cilium Assembly Pathway Diagram
 Cooperation Of Prefoldin And TriC/CCT In Actin And Tubulin Folding Pathway antibodies  Cooperation Of Prefoldin And TriC/CCT In Actin And Tubulin Folding Pathway Diagram
Diseases associated with anti-TUBA4A antibodyOrgans/Tissues associated with anti-TUBA4A antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >9 publications with TUBA4A and Nervous System Diseases
 Brain Diseases Antibodies  >6 publications with TUBA4A and Brain Diseases
 Ataxia Antibodies  >1 publications with TUBA4A and Ataxia
 Nerve Degeneration Antibodies  >1 publications with TUBA4A and Nerve Degeneration
 Disease Models, Animal Antibodies  >1 publications with TUBA4A and Disease Models, Animal
 Memory Disorders Antibodies  >1 publications with TUBA4A and Memory Disorders
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >5 publications with TUBA4A and Brain
 Nerve Antibodies  >2 publications with TUBA4A and Nerve
 Eye Antibodies  >1 publications with TUBA4A and Eye
 Blood Antibodies  >1 publications with TUBA4A and Blood
 Testis Antibodies  >1 publications with TUBA4A and Testis
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