NP_001294952.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
tensin-1 isoform 3
NCBI Official Synonym Full Names
tensin 1
NCBI Official Synonym Symbols
TNS; MXRA6; MST091; MST122; MST127; MSTP091; MSTP122; MSTP127; PPP1R155 [Similar Products]
NCBI Protein Information
tensin-1
UniProt Protein Name
Tensin-1
UniProt Synonym Gene Names
UniProt Entry Name
TENS1_HUMAN
NCBI Summary for TNS1
The protein encoded by this gene localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
UniProt Comments for TNS1
tensin 1: May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton.
Protein type: Motility/polarity/chemotaxis; Adaptor/scaffold
Chromosomal Location of Human Ortholog: 2q35-q36
Cellular Component: cell surface; cytoplasm; cytoskeleton; focal adhesion
Molecular Function: actin binding; protein binding
Biological Process: cell-substrate junction assembly
Research Articles on TNS1
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Products associated with anti-TNS1 antibody
Pathways associated with anti-TNS1 antibody
Diseases associated with anti-TNS1 antibody
Organs/Tissues associated with anti-TNS1 antibody
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