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anti-TXN2 antibody :: Rabbit Thioredoxin Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS1494888
Unit / Price
0.05 mL  /  $120 +1 FREE 8GB USB
0.1 mL  /  $160 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Thioredoxin (TXN2), Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-human Thioredoxin, mitochondrial polyclonal Antibody(TXN2)

 Product Synonym Names    MTRX; Mt-Trx; Thioredoxin-2; TXN2; TRX2
 Product Gene Name   

anti-TXN2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    609063
 3D Structure    ModBase 3D Structure for Q99757
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Storage Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
 Conjugate    Non-conjugated
 Immunogen    Recombinant human Thioredoxin, mitochondrial protein (1-166aa)
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-22980 / sc-50336 / sc-50336
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-TXN2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-TXN2 antibody

   Has an anti-apoptotic function and plays an important role in the regulation of mitochondrial membrane potential. Could be involved in the resistance to anti-tumor agents. Possesses a dithiol-reducing activity.
 Applications Tested/Suitable for anti-TXN2 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-TXN2 antibody    Recommended dilution: WB:1:500-5000
IHC:1:20-1:200
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 Western Blot (WB) of anti-TXN2 antibody    All lanes: Thioredoxin, mitochondrial antibody at 3ug/ml
Lane 1:mouse liver tissue
Lane 2:rat brain tissue
Lane 3:mouse kidney tissue
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 18kDa
Observed band size: 18kDa

anti-TXN2 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-TXN2 antibody    Immunohistochemistry of paraffin-embedded human tonsil using MBS1494888 at dilution 1:100
anti-TXN2 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-TXN2 antibody    Immunohistochemistry of paraffin-embedded rectum using MBS1494888 at dilution 1:100
anti-TXN2 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-TXN2 antibody    Immunohistochemistry of paraffin-embedded human pancreas using MBS1494888 at dilution 1:100
anti-TXN2 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for TXN2. It may not necessarily be applicable to this product.
 NCBI GI #    21361403
 NCBI GeneID    25828
 NCBI Accession #    NP_036605.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_012473.3 [Other Products]
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 UniProt Primary Accession #    Q99757 [Other Products]
 UniProt Secondary Accession #    Q5JZA0; Q6FH60; Q9UH29 [Other Products]
 UniProt Related Accession #    Q99757 [Other Products]
 Molecular Weight    18,383 Da
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 NCBI Official Full Name    thioredoxin, mitochondrial
 NCBI Official Synonym Full Names    thioredoxin 2
 NCBI Official Symbol    TXN2 [Similar Products]
 NCBI Official Synonym Symbols   
MTRX; TRX2; MT-TRX
[Similar Products]
 NCBI Protein Information    thioredoxin, mitochondrial
 UniProt Protein Name    Thioredoxin, mitochondrial
 UniProt Synonym Protein Names   
Thioredoxin-2
 Protein Family    Thioredoxin
 UniProt Gene Name    TXN2 [Similar Products]
 UniProt Synonym Gene Names    TRX2; MTRX; Mt-Trx [Similar Products]
 UniProt Entry Name    THIOM_HUMAN
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 NCBI Summary for TXN2    This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. [provided by RefSeq, Jul 2008]
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 UniProt Comments for TXN2    TXN2: Has an anti-apoptotic function and plays an important role in the regulation of mitochondrial membrane potential. Could be involved in the resistance to anti-tumor agents. Possesses a dithiol-reducing activity. Belongs to the thioredoxin family.

Protein type: Oxidoreductase

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: cell soma; dendrite; mitochondrial matrix; mitochondrion; nucleolus

Molecular Function: oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor; peptide-methionine (R)-S-oxide reductase activity; peptide-methionine-(S)-S-oxide reductase activity; protein binding; protein complex binding; protein disulfide oxidoreductase activity

Biological Process: cell redox homeostasis; cellular response to nutrient levels; glycerol ether metabolic process; protein folding; response to axon injury; response to drug; response to glucose stimulus; response to hormone stimulus; response to hypoxia; response to nutrient; response to organic cyclic substance; response to reactive oxygen species; sulfate assimilation
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 Research Articles on TXN2    1. Thioredoxin 2 Is a Novel E2-Interacting Protein That Inhibits the Replication of Classical Swine Fever Virus by promoting the nuclear translocation of the p65 subunit of NF-kappaB.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-TXN2 antibodyPathways associated with anti-TXN2 antibody
 Reference Product  PubMed Publications
 PRDX3 antibody  >10 publications with TXN2 and PRDX3
 TXNRD2 antibody  >10 publications with TXN2 and TXNRD2
 SOD2 antibody  >9 publications with TXN2 and SOD2
 MAP3K5 antibody  >8 publications with TXN2 and MAP3K5
 PRDX1 antibody  >2 publications with TXN2 and PRDX1
 TFAM antibody  >2 publications with TXN2 and TFAM
 EIF4E antibody  >1 publications with TXN2 and EIF4E
 Products by Pathway  Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 Detoxification Of Reactive Oxygen Species Pathway antibodies  Detoxification Of Reactive Oxygen Species Pathway Diagram
 Oxidative Stress Pathway antibodies  Oxidative Stress Pathway Diagram
Diseases associated with anti-TXN2 antibodyOrgans/Tissues associated with anti-TXN2 antibody
 Disease Name  Pubmed Publications
 Death Antibodies  >22 publications with TXN2 and Death
 Nervous System Diseases Antibodies  >10 publications with TXN2 and Nervous System Diseases
 Brain Diseases Antibodies  >6 publications with TXN2 and Brain Diseases
 Disease Models, Animal Antibodies  >6 publications with TXN2 and Disease Models, Animal
 Heart Diseases Antibodies  >5 publications with TXN2 and Heart Diseases
 Inflammation Antibodies  >5 publications with TXN2 and Inflammation
 Necrosis Antibodies  >5 publications with TXN2 and Necrosis
 Liver Diseases Antibodies  >4 publications with TXN2 and Liver Diseases
 Lung Neoplasms Antibodies  >3 publications with TXN2 and Lung Neoplasms
 Fibrosis Antibodies  >3 publications with TXN2 and Fibrosis
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >12 publications with TXN2 and Liver
 Brain Antibodies  >12 publications with TXN2 and Brain
 Vascular Antibodies  >10 publications with TXN2 and Vascular
 Heart Antibodies  >9 publications with TXN2 and Heart
 Blood Antibodies  >7 publications with TXN2 and Blood
 Muscle Antibodies  >7 publications with TXN2 and Muscle
 Lung Antibodies  >5 publications with TXN2 and Lung
 Eye Antibodies  >5 publications with TXN2 and Eye
 Lymph Node Antibodies  >4 publications with TXN2 and Lymph Node
 Nerve Antibodies  >4 publications with TXN2 and Nerve
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