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anti-Trib1 antibody :: Goat Trib1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS422700
Western Blot (WB)
Unit / Price
0.1 mg  /  $300 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Trib1, Polyclonal Antibody

 Also Known As   

Goat anti-Trib1 (mouse) (aa304-317) Antibody

 Product Synonym Names    Goat Anti-TRIB1 / SKIP1 Antibody; Trib1; tribbles homolog 1 (Drosophila); A530090O15Rik; TRB-1; Trb1; tribbles homolog 1; A530090O15Rik antibody; Trb1 antibody; TRB-1 antibody; tribbles homolog 1 antibody; tribbles homolog 1 (Drosophila) antibody; Trib1 antibody; Trib1 (mouse) (aa304-317)
 Product Gene Name   

anti-Trib1 antibody

[Similar Products]
 Antibody/Peptide Pairs    Trib1 peptide (MBS427469) is used for blocking the activity of Trib1 antibody (MBS422700)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    PEHVSPKARC LIRS
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 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Tested: Mouse; Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow
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 Purity/Purification    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
 Form/Format    Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
 Concentration    100ug specific antibody in 200ul (lot specific)
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 Immunogen    Peptide with sequence PEHVSPKARCLIRS, from the internal region of the protein sequence according to NP_653132.1.
 Epitope    Internal region
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 Preparation and Storage    Aliquot and store at -20 degree C. Minimize freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-Trib1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-Trib1 antibody   

Peptide ELISA (EIA), Western Blot (WB)

 Application Notes for anti-Trib1 antibody    Peptide ELISA: Antibody detection limit dilution 1: 8000.
Western Blot: Approx 42kDa band observed in lysates of cell line NIH3T3 (calculated MW of 41.3kDa according to NP_653132.1). Recommended concentration: 0.1-0.3ug/ml.
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 Western Blot (WB) of anti-Trib1 antibody    (0.1ug/ml) staining of NIH3T3 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
anti-Trib1 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for Trib1. It may not necessarily be applicable to this product.
 NCBI GI #    21362355
 NCBI GeneID    211770
 NCBI Accession #    NP_653132.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_144549.4 [Other Products]
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 UniProt Secondary Accession #    Q8BFS7; Q8BJR9; Q8BZX3; Q91W04 [Other Products]
 UniProt Related Accession #    Q8K4K4 [Other Products]
 Molecular Weight    23,907 Da
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 NCBI Official Full Name    tribbles homolog 1
 NCBI Official Synonym Full Names    tribbles pseudokinase 1
 NCBI Official Symbol    Trib1 [Similar Products]
 NCBI Official Synonym Symbols   
Trb1; TRB-1; A530090O15Rik
[Similar Products]
 NCBI Protein Information    tribbles homolog 1
 UniProt Protein Name    Tribbles homolog 1
 Protein Family    Tribbles
 UniProt Gene Name    Trib1 [Similar Products]
 UniProt Synonym Gene Names    TRB-1 [Similar Products]
 UniProt Entry Name    TRIB1_MOUSE
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 UniProt Comments for Trib1    TRB1: Interacts with MAPK kinases and regulates activation of MAP kinases. May not display kinase activity. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. Tribbles subfamily.

Protein type: Kinase, protein; Protein kinase, CAMK; Protein kinase, Ser/Thr (non-receptor); CAMK group; Trbl family

Cellular Component: cytoplasm; nucleus

Molecular Function: ATP binding; mitogen-activated protein kinase kinase binding; protein kinase activity; protein kinase inhibitor activity; transcription factor binding; ubiquitin protein ligase binding; ubiquitin-protein ligase regulator activity

Biological Process: JNK cascade; negative regulation of lipopolysaccharide-mediated signaling pathway; negative regulation of neutrophil differentiation; negative regulation of protein kinase activity; negative regulation of smooth muscle cell migration; negative regulation of smooth muscle cell proliferation; negative regulation of transcription factor activity; positive regulation of eosinophil differentiation; positive regulation of macrophage differentiation; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of ubiquitin-protein ligase activity; protein amino acid phosphorylation; regulation of catalytic activity; regulation of MAP kinase activity; response to lipopolysaccharide
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 Research Articles on Trib1    1. The Liver Clock Controls Cholesterol Homeostasis through Trib1 Protein-mediated Regulation of PCSK9/Low Density Lipoprotein Receptor (LDLR) Axis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-Trib1 antibodyDiseases associated with anti-Trib1 antibody
 Reference Product  PubMed Publications
 Cebpb antibody  >2 publications with Trib1 and Cebpb
 Disease Name  Pubmed Publications
 Heart Diseases Antibodies  >16 publications with Trib1 and Heart Diseases
 Coronary Artery Disease Antibodies  >14 publications with Trib1 and Coronary Artery Disease
 Inflammation Antibodies  >12 publications with Trib1 and Inflammation
 Liver Diseases Antibodies  >9 publications with Trib1 and Liver Diseases
 Fatty Liver Antibodies  >7 publications with Trib1 and Fatty Liver
 Prostatic Neoplasms Antibodies  >3 publications with Trib1 and Prostatic Neoplasms
 Cell Transformation, Neoplastic Antibodies  >3 publications with Trib1 and Cell Transformation, Neoplastic
 Disease Models, Animal Antibodies  >3 publications with Trib1 and Disease Models, Animal
 Kidney Diseases Antibodies  >2 publications with Trib1 and Kidney Diseases
 Lung Diseases Antibodies  >2 publications with Trib1 and Lung Diseases
Organs/Tissues associated with anti-Trib1 antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >51 publications with Trib1 and Blood
 Other Antibodies  >20 publications with Trib1 and Other
 Liver Antibodies  >17 publications with Trib1 and Liver
 Bone Antibodies  >11 publications with Trib1 and Bone
 Bone Marrow Antibodies  >7 publications with Trib1 and Bone Marrow
 Brain Antibodies  >5 publications with Trib1 and Brain
 Kidney Antibodies  >4 publications with Trib1 and Kidney
 Lung Antibodies  >3 publications with Trib1 and Lung
 Eye Antibodies  >2 publications with Trib1 and Eye
 Embryonic Tissue Antibodies  >2 publications with Trib1 and Embryonic Tissue
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