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anti-TNFRSF1A antibody :: Rabbit anti-Human Tumor Necrosis Factor Receptor Superfamily Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2027735 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $90 +1 FREE 8GB USB
0.02 mg  /  $105 +1 FREE 8GB USB
0.05 mg  /  $135 +1 FREE 8GB USB
0.1 mg  /  $165 +1 FREE 8GB USB
0.2 mg  /  $230 +1 FREE 8GB USB
1 mg  /  $520 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Tumor Necrosis Factor Receptor Superfamily (TNFRSF1A), Polyclonal Antibody

★Popular Item★
 Also Known As   

Polyclonal Antibody to Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A)

 Product Gene Name   

anti-TNFRSF1A antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    The target protein is fused with two N-terminal Tags, His-tag and T7-tag and its sequence is listed below.
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGS- CGK STPEKEGELE GTTTKPLAPN PSFSPTPGFT PTLGFSPVPS STFTSSSTYT PGDCPNFAAP RREVAPPYQG ADPILATALA SDPIPNPLQK WEDSAHKPQS LDTDDPATLY AVVENVPPLR WKEFVRRLGL SDHEIDRLEL
 OMIM    M58286 mRNA
 3D Structure    ModBase 3D Structure for P19438
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    The antibody is a rabbit polyclonal antibody raised against TNFRSF1A. It has beenselected for its ability to recognize TNFRSF1A in immunohistochemical staining andwestern blotting.
 Purity/Purification    Affinity Chromatography
 Form/Format    Liquid
 Concentration    200ug/ml (lot specific)
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 Fragment    TNFRSF1A (Cys248~Met428)
 Organism Species    Homo sapiens (Human)
 Conjugate    No Conjugate
 Immunogen    Recombinant TNFRSF1A (Cys248~Met428) expressed in E Coli.
 Conjugated Antibody    The APC conjugated antibody version of this item is also available as catalog #MBS2055948
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 Preparation and Storage    Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
 Other Notes    Small volumes of anti-TNFRSF1A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-TNFRSF1A antibody    Knock-Out Validation Antibody
 Applications Tested/Suitable for anti-TNFRSF1A antibody   

Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)

 Application Notes for anti-TNFRSF1A antibody    Western blotting: 0.5-5ug/mL
Immunocytochemistry in formalin fixed cells: 5-20ug/mL
Immunohistochemistry in formalin fixed frozen section: 5-20ug/mL
Immunohistochemistry in paraffin section: 5-20ug/mL
Optimal working dilutions must be determined by end user.
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 Western Blot (WB) Knockout Verification of anti-TNFRSF1A antibody    Knockout Verification: Lane 1: Wild-type Hela cell lysate; Lane 2: TNFRSF1A knockout Hela cell lysate; Predicted MW: 50,38,25kDa Observed MW: 23kDa Primary Ab: 3ug/ml Rabbit Anti-Human TNFRSF1A Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
anti-TNFRSF1A antibody Western Blot (WB) Knockout Verification (WB) image
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 Western Blot (WB) of anti-TNFRSF1A antibody    Western Blot; Sample: Lane1: Human Hela Cells; Lane2: Human Jurkat Cells.
anti-TNFRSF1A antibody Western Blot (WB) (WB) image
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 Western Blot (WB) of anti-TNFRSF1A antibody    Western Blot; Sample: Recombinant TNFRSF1A, Human.
anti-TNFRSF1A antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-TNFRSF1A antibody    FITC staining on IHC-P Simple: Hela cells)
anti-TNFRSF1A antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-TNFRSF1A antibody    DAB staining on IHC-P; Samples: Human Kidney Tissue
anti-TNFRSF1A antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-TNFRSF1A antibody    DAB staining on IHC-P; Samples: Human Lung Cancer Tissue
anti-TNFRSF1A antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-TNFRSF1A antibody    DAB staining on IHC-P; Samples: Human Brain Tissue.
anti-TNFRSF1A antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for TNFRSF1A. It may not necessarily be applicable to this product.
 NCBI GI #    4507575
 NCBI GeneID    7132
 NCBI Accession #    NP_001056.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001065.3 [Other Products]
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 UniProt Primary Accession #    P19438 [Other Products]
 UniProt Secondary Accession #    Q9UCA4; A8K4X3; B2RDE4; B3KPQ1; B4DQB7; B4E309; B5M0B5; D3DUR1 [Other Products]
 UniProt Related Accession #    P19438 [Other Products]
 Molecular Weight    24,194 Da
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 NCBI Official Full Name    tumor necrosis factor receptor superfamily member 1A isoform 1
 NCBI Official Synonym Full Names    TNF receptor superfamily member 1A
 NCBI Official Symbol    TNFRSF1A [Similar Products]
 NCBI Official Synonym Symbols   
FPF; p55; p60; TBP1; TNF-R; TNFAR; TNFR1; p55-R; CD120a; TNFR55; TNFR60; TNF-R-I; TNF-R55
[Similar Products]
 NCBI Protein Information    tumor necrosis factor receptor superfamily member 1A
 UniProt Protein Name    Tumor necrosis factor receptor superfamily member 1A
 UniProt Synonym Protein Names   
Tumor necrosis factor receptor 1; TNF-R1
 Protein Family    Tumor necrosis factor receptor superfamily
 UniProt Gene Name    TNFRSF1A [Similar Products]
 UniProt Synonym Gene Names    TNFAR; TNFR1; TNF-R1; TNF-RI; TNFR-I; TBPI [Similar Products]
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 NCBI Summary for TNFRSF1A    This gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor trimerization and activation, which plays a role in cell survival, apoptosis, and inflammation. Proteolytic processing of the encoded receptor results in release of the soluble form of the receptor, which can interact with free tumor necrosis factor alpha to inhibit inflammation. Mutations in this gene underlie tumor necrosis factor receptor-associated periodic syndrome (TRAPS), characterized by fever, abdominal pain and other features. Mutations in this gene may also be associated with multiple sclerosis in human patients. [provided by RefSeq, Sep 2016]
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 UniProt Comments for TNFRSF1A    Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
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 Research Articles on TNFRSF1A    1. Elevated level of soluble tumor necrosis factor receptors 1 and lower level of leptin are associated with higher developmental outcomes in infants between the ages of 6 and 24 months.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-TNFRSF1A antibodyPathways associated with anti-TNFRSF1A antibody
 Reference Product  PubMed Publications
 TNF antibody  >351 publications with TNFRSF1A and TNF
 TRADD antibody  >12 publications with TNFRSF1A and TRADD
 TRAF2 antibody  >10 publications with TNFRSF1A and TRAF2
 IKBKB antibody  >9 publications with TNFRSF1A and IKBKB
 LTA antibody  >6 publications with TNFRSF1A and LTA
 TNFRSF25 antibody  >5 publications with TNFRSF1A and TNFRSF25
 RIPK1 antibody  >5 publications with TNFRSF1A and RIPK1
 MAPK1 antibody  >5 publications with TNFRSF1A and MAPK1
 RALBP1 antibody  >5 publications with TNFRSF1A and RALBP1
 ERAP1 antibody  >5 publications with TNFRSF1A and ERAP1
 Products by Pathway  Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimers Disease Pathway antibodies  Alzheimers Disease Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
Diseases associated with anti-TNFRSF1A antibodyOrgans/Tissues associated with anti-TNFRSF1A antibody
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >500 publications with TNFRSF1A and Necrosis
 Inflammation Antibodies  >163 publications with TNFRSF1A and Inflammation
 Fever Antibodies  >140 publications with TNFRSF1A and Fever
 Autoimmune Diseases Antibodies  >77 publications with TNFRSF1A and Autoimmune Diseases
 Pain Antibodies  >54 publications with TNFRSF1A and Pain
 Cardiovascular Diseases Antibodies  >53 publications with TNFRSF1A and Cardiovascular Diseases
 Neoplasms Antibodies  >37 publications with TNFRSF1A and Neoplasms
 Heart Diseases Antibodies  >32 publications with TNFRSF1A and Heart Diseases
 Drug Toxicity Antibodies  >30 publications with TNFRSF1A and Drug Toxicity
 Lung Diseases Antibodies  >28 publications with TNFRSF1A and Lung Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >184 publications with TNFRSF1A and Blood
 Brain Antibodies  >46 publications with TNFRSF1A and Brain
 Liver Antibodies  >45 publications with TNFRSF1A and Liver
 Skin Antibodies  >42 publications with TNFRSF1A and Skin
 Vascular Antibodies  >40 publications with TNFRSF1A and Vascular
 Muscle Antibodies  >38 publications with TNFRSF1A and Muscle
 Bone Antibodies  >38 publications with TNFRSF1A and Bone
 Lung Antibodies  >33 publications with TNFRSF1A and Lung
 Bone Marrow Antibodies  >26 publications with TNFRSF1A and Bone Marrow
 Heart Antibodies  >26 publications with TNFRSF1A and Heart
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