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anti-INPP5A antibody :: Rabbit anti-Human Type I inositol 1,4,5-trisphosphate 5-phosphatase Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS1489302
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Type I inositol 1,4,5-trisphosphate 5-phosphatase (INPP5A), Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-human Type I inositol 1, 4, 5-trisphosphate 5-phosphatase polyclonal Antibody

 Product Synonym Names    5PTase; INPP5A
 Product Gene Name   

anti-INPP5A antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    600106
 3D Structure    ModBase 3D Structure for Q14642
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Caprylic Acid Ammonium Sulfate Precipitation Purified
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 Storage Buffer    Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Conjugate    Non-conjugated
 Immunogen    Recombinant human Type I inositol 1,4,5-trisphosphate 5-phosphatase protein
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-12302 / sc-12305
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-INPP5A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-INPP5A antibody

   Major isoenzyme hydrolyzing the calcium-mobilizing second messenger Ins(1,4,5)P3, this is a signal-terminating reaction.
 Applications Tested/Suitable for anti-INPP5A antibody   

ELISA (EIA), Immunohistochemistry (IHC)

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 Immunohistochemistry (IHC) of anti-INPP5A antibody    Immunohistochemistry of paraffin-embedded human kidney tissue using MBS1489302 at dilution 1:100
anti-INPP5A antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-INPP5A antibody    Immunohistochemistry of paraffin-embedded human brain tissue using MBS1489302 at dilution 1:100
anti-INPP5A antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-INPP5A antibody    Immunofluorescent analysis of HepG2 cells using MBS1489302 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-INPP5A antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for INPP5A. It may not necessarily be applicable to this product.
 NCBI GI #    109702906
 NCBI GeneID    3632
 NCBI Accession #    NP_005530.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_005539.3 [Other Products]
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 UniProt Primary Accession #    Q14642 [Other Products]
 UniProt Secondary Accession #    Q14640; Q5JSF1; D3DXI3 [Other Products]
 UniProt Related Accession #    Q14642 [Other Products]
 Molecular Weight    47,820 Da [Similar Products]
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 NCBI Official Full Name    type I inositol 1,4,5-trisphosphate 5-phosphatase
 NCBI Official Synonym Full Names    inositol polyphosphate-5-phosphatase A
 NCBI Official Symbol    INPP5A [Similar Products]
 NCBI Official Synonym Symbols   
5PTASE
[Similar Products]
 NCBI Protein Information    type I inositol 1,4,5-trisphosphate 5-phosphatase
 UniProt Protein Name    Type I inositol 1,4,5-trisphosphate 5-phosphatase
 Protein Family    Type I inositol 1,4,5-trisphosphate 5-phosphatase
 UniProt Gene Name    INPP5A [Similar Products]
 UniProt Synonym Gene Names    5PTase [Similar Products]
 UniProt Entry Name    I5P1_HUMAN
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 NCBI Summary for INPP5A    The protein encoded by this gene is a membrane-associated type I inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. [provided by RefSeq, Jul 2008]
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 UniProt Comments for INPP5A    INPP5A: Major isoenzyme hydrolyzing the calcium-mobilizing second messenger Ins(1,4,5)P3, this is a signal-terminating reaction. Belongs to the inositol 1,4,5-trisphosphate 5- phosphatase type I family.

Protein type: Carbohydrate Metabolism - inositol phosphate; EC 3.1.3.56; Phosphatase (non-protein)

Chromosomal Location of Human Ortholog: 10q26.3

Cellular Component: membrane; plasma membrane

Molecular Function: inositol-polyphosphate 5-phosphatase activity; PH domain binding; protein binding

Biological Process: inositol phosphate metabolic process; phosphoinositide dephosphorylation
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 Research Articles on INPP5A    1. NPP5Amay play a role in development and progression of cutaneous squamous cell carcinoma tumors
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-INPP5A antibodyPathways associated with anti-INPP5A antibody
 Reference Product  PubMed Publications
 PLCB1 antibody  >2 publications with INPP5A and PLCB1
 PLCB4 antibody  >1 publications with INPP5A and PLCB4
 PLCD1 antibody  >1 publications with INPP5A and PLCD1
 ITPKB antibody  >1 publications with INPP5A and ITPKB
 ITPKA antibody  >1 publications with INPP5A and ITPKA
 Products by Pathway  Pathway Diagram
 1D-myo-inositol Hexakisphosphate Biosynthesis II (mammalian) Pathway antibodies  1D-myo-inositol Hexakisphosphate Biosynthesis II (mammalian) Pathway Diagram
 1D-myo-inositol Hexakisphosphate Biosynthesis II (mammalian) Pathway antibodies  1D-myo-inositol Hexakisphosphate Biosynthesis II (mammalian) Pathway Diagram
 D-myo-inositol (1,3,4)-trisphosphate Biosynthesis Pathway antibodies  D-myo-inositol (1,3,4)-trisphosphate Biosynthesis Pathway Diagram
 D-myo-inositol (1,3,4)-trisphosphate Biosynthesis Pathway antibodies  D-myo-inositol (1,3,4)-trisphosphate Biosynthesis Pathway Diagram
 D-myo-inositol (1,4,5)-trisphosphate Degradation Pathway antibodies  D-myo-inositol (1,4,5)-trisphosphate Degradation Pathway Diagram
 D-myo-inositol (1,4,5)-trisphosphate Degradation Pathway antibodies  D-myo-inositol (1,4,5)-trisphosphate Degradation Pathway Diagram
 Inositol Phosphate Metabolism Pathway antibodies  Inositol Phosphate Metabolism Pathway Diagram
 Inositol Phosphate Metabolism Pathway antibodies  Inositol Phosphate Metabolism Pathway Diagram
 Inositol Phosphate Metabolism Pathway antibodies  Inositol Phosphate Metabolism Pathway Diagram
 Inositol Phosphate Metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => Myo-inositol Pathway antibodies  Inositol Phosphate Metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => Myo-inositol Pathway Diagram
Diseases associated with anti-INPP5A antibodyOrgans/Tissues associated with anti-INPP5A antibody
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >1 publications with INPP5A and Breast Neoplasms
 Kidney Diseases Antibodies  >1 publications with INPP5A and Kidney Diseases
 Inflammation Antibodies  >1 publications with INPP5A and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >5 publications with INPP5A and Brain
 Skin Antibodies  >3 publications with INPP5A and Skin
 Liver Antibodies  >1 publications with INPP5A and Liver
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