NP_003083.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
25,486 Da
NCBI Official Full Name
U2 small nuclear ribonucleoprotein B''
NCBI Official Synonym Full Names
small nuclear ribonucleoprotein polypeptide B
NCBI Official Synonym Symbols
NCBI Protein Information
U2 small nuclear ribonucleoprotein B''
UniProt Protein Name
U2 small nuclear ribonucleoprotein B''
UniProt Synonym Gene Names
UniProt Entry Name
RU2B_HUMAN
NCBI Summary for SNRPB2
The protein encoded by this gene associates with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presence of snRNP-A'. The encoded protein may play a role in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for SNRPB2
snRNP B2: a small nuclear ribonucleoprotein. Involved in pre-mRNA splicing. This protein is associated with snRNP U2. It binds stem loop IV of U2 snRNA only in presence of the A' protein.
Protein type: RNA processing; RNA splicing; Spliceosome; RNA-binding
Chromosomal Location of Human Ortholog: 20p12.1
Cellular Component: nucleolus; nucleoplasm; snRNP U2; spliceosome
Molecular Function: nucleotide binding; protein binding
Biological Process: gene expression; nuclear mRNA splicing, via spliceosome; positive regulation of defense response to virus by host; RNA splicing
Research Articles on SNRPB2
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Products associated with anti-SNRPB2 antibody
Pathways associated with anti-SNRPB2 antibody
Diseases associated with anti-SNRPB2 antibody
Organs/Tissues associated with anti-SNRPB2 antibody
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