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anti-UHMK1 antibody :: Rabbit U2AF homology motif (UHM) kinase 1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS711043 anti-UHMK1 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

U2AF homology motif (UHM) kinase 1 (UHMK1), Polyclonal Antibody

 Also Known As   

Rabbit anti-human U2AF homology motif (UHM) kinase 1 polyclonal Antibody

 Product Synonym Names    U2AF homology motif (UHM) kinase 1; UHMK1; KIS; Kist
 Product Gene Name   

anti-UHMK1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    608849
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human UHMK1
 Storage Buffer    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-103915 / sc-103917 / sc-130909
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-UHMK1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-UHMK1 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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NCBI/Uniprot data below describe general gene information for UHMK1. It may not necessarily be applicable to this product.
 NCBI GI #    119611113
 NCBI GeneID    127933
 NCBI Accession #    EAW90707.1 [Other Products]
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 UniProt Secondary Accession #    Q96C22; A8K8K4; G3V1M1 [Other Products]
 UniProt Related Accession #    Q8TAS1 [Other Products]
 Molecular Weight    39,044 Da [Similar Products]
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 NCBI Official Full Name    U2AF homology motif (UHM) kinase 1, isoform CRA_b
 NCBI Official Synonym Full Names    U2AF homology motif (UHM) kinase 1
 NCBI Official Symbol    UHMK1 [Similar Products]
 NCBI Official Synonym Symbols   
KIS; KIST; P-CIP2
[Similar Products]
 NCBI Protein Information    serine/threonine-protein kinase Kist; KIS protein kinase; PAM COOH-terminal interactor protein 2; kinase interacting with leukemia-associated gene (stathmin)
 UniProt Protein Name    Serine/threonine-protein kinase Kist
 UniProt Synonym Protein Names   
Kinase interacting with stathmin; PAM COOH-terminal interactor protein 2; P-CIP2; U2AF homology motif kinase 1
 Protein Family    Serine/threonine-protein kinase
 UniProt Gene Name    UHMK1 [Similar Products]
 UniProt Synonym Gene Names    KIS; KIST; P-CIP2 [Similar Products]
 UniProt Entry Name    UHMK1_HUMAN
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 NCBI Summary for UHMK1    The gene encodes a serine/threonine protein kinase that promotes cell cycle progression through G1 by phosphorylation of the cyclin-dependent kinase inhibitor 1B (p27Kip1), which causes nuclear export and degradation. The encoded protein is also thought to function in the adult nervous system and the gene has been associated with schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
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 UniProt Comments for UHMK1    KIS: a unique kinase that possesses an RNP type RNA-recognition motif (RRM). A proline-directed kinase with a specificity different from the MAP kinases and CDKs. May be involved in trafficking and/or processing of RNA.

Protein type: Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Protein kinase, Other; EC 2.7.11.1; Other group; Other-Unique family

Chromosomal Location of Human Ortholog: 1q23.3

Cellular Component: dendrite cytoplasm; axon; nucleus

Molecular Function: transferase activity; ribonucleoprotein binding; protein serine/threonine kinase activity; protein binding; enzyme binding; RNA binding; ATP binding

Biological Process: positive regulation of translational initiation; peptidyl-serine phosphorylation; protein amino acid autophosphorylation; cell cycle arrest; neurite development; regulation of protein export from nucleus
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 Research Articles on UHMK1    1. Moreover, we showed that CATS and KIS antagonize the transactivation capacity of CALM/AF10.In summary, our results show that CATS interacts with and is a substrate for KIS, suggesting that KIS regulates CATS function
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-UHMK1 antibodyDiseases associated with anti-UHMK1 antibody
 Reference Product  PubMed Publications
 CDKN1B antibody  >8 publications with UHMK1 and CDKN1B
 PAM antibody  >5 publications with UHMK1 and PAM
 STMN1 antibody  >1 publications with UHMK1 and STMN1
 Disease Name  Pubmed Publications
 Infertility, Male Antibodies  >1 publications with UHMK1 and Infertility, Male
 Liver Diseases Antibodies  >1 publications with UHMK1 and Liver Diseases
 Infertility, Female Antibodies  >1 publications with UHMK1 and Infertility, Female
 Brain Diseases Antibodies  >1 publications with UHMK1 and Brain Diseases
 Weight Gain Antibodies  >1 publications with UHMK1 and Weight Gain
 Neoplasms, Experimental Antibodies  >1 publications with UHMK1 and Neoplasms, Experimental
 Carcinoma, Hepatocellular Antibodies  >1 publications with UHMK1 and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >1 publications with UHMK1 and Liver Neoplasms
 Liver Neoplasms, Experimental Antibodies  >1 publications with UHMK1 and Liver Neoplasms, Experimental
Organs/Tissues associated with anti-UHMK1 antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >9 publications with UHMK1 and Brain
 Blood Antibodies  >7 publications with UHMK1 and Blood
 Vascular Antibodies  >3 publications with UHMK1 and Vascular
 Muscle Antibodies  >2 publications with UHMK1 and Muscle
 Lung Antibodies  >2 publications with UHMK1 and Lung
 Nerve Antibodies  >2 publications with UHMK1 and Nerve
 Heart Antibodies  >2 publications with UHMK1 and Heart
 Liver Antibodies  >2 publications with UHMK1 and Liver
 Bone Marrow Antibodies  >1 publications with UHMK1 and Bone Marrow
 Prostate Antibodies  >1 publications with UHMK1 and Prostate
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