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anti-U2AF59 antibody :: Rabbit U2AF59 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS5400198 anti-U2AF59 antibody
Unit / Price
0.1 mg FITC  /  $495 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

U2AF59, Polyclonal Antibody

 Also Known As   

U2AF59 Antibody FITC-Conjugated

 Product Synonym Names    S. pombe splicing factor U2 59 kDa subunit; Schzosacharomyces pombe splicing factor U2 auxiliary factor; U2 auxiliary factor 59 kDa subunit; U2 snRNP auxiliary factor large subunit; mis11; prp2
 Product Gene Name   

anti-U2AF59 antibody

[Similar Products]
 Matching Pairs    Antibody: U2AF59 (MBS5400198)
Positive Control: U2AF59 (MBS543362)
 Antibody/Peptide Pairs    U2AF59 peptide (MBS544631) is used for blocking the activity of U2AF59 antibody (MBS5400198)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for P36629
 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Saccharomyces cerevisae
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 Form/Format    FITC-Conjugated
 Concentration    0.75-1.13 ug/ul in antibody stabilization buffer (lot specific)
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 Immunogen    Synthetic peptide taken within amino acid region 480-520 on yeast U2AF59 protein.
 Molecular Function    mRNA binding, snoRNA binding, nucleotide binding
 Structure    Forms a heterodimer with the U2AF small subunit. Can also form a homodimer. U2AF large subunit (U2AF59), U2AF small subunit (U2AF23) and SF1 (bpb1) interact to form a complex required for complex A formation. Interacts with wat1/pop3.
 Subcellular Location    Nucleus
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 Preparation and Storage    -20 degree C for long term storage
 Other Notes    Small volumes of anti-U2AF59 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-U2AF59 antibody

   FITC-Conjugated Splicing factor U2AF 59 kDa subunit Antibody
Necessary for the splicing of pre-mRNA. The SF1-U2AF59-U2AF23 complex has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.
 Applications Tested/Suitable for anti-U2AF59 antibody   

ELISA (EIA), IMM, Western Blot (WB)

 Application Notes for anti-U2AF59 antibody    Dot Blot: 1:10,000
ELISA: 1:10,000
Immunoprecipitation: 1:200
Western Blot: 1:500-1:750
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NCBI/Uniprot data below describe general gene information for U2AF59. It may not necessarily be applicable to this product.
 NCBI GI #    549144
 NCBI GeneID    2539645
 NCBI Accession #    P36629.1 [Other Products]
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 UniProt Primary Accession #    P36629 [Other Products]
 UniProt Secondary Accession #    Q9UTU7 [Other Products]
 UniProt Related Accession #    P36629 [Other Products]
 Molecular Weight    58,933 Da
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 NCBI Official Full Name    Splicing factor U2AF 59 kDa subunit
 NCBI Official Symbol    prp2 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    U2AF large subunit (U2AF-59)
 UniProt Protein Name    Splicing factor U2AF 59 kDa subunit
 UniProt Synonym Protein Names   
U2 auxiliary factor 59 kDa subunit; U2AF59; U2 snRNP auxiliary factor large subunit
 UniProt Gene Name    prp2 [Similar Products]
 UniProt Synonym Gene Names    mis11; U2AF59 [Similar Products]
 UniProt Entry Name    U2AF2_SCHPO
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 UniProt Comments for U2AF59    Necessary for the splicing of pre-mRNA. The SF1-U2AF59-U2AF23 complex has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.
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 Research Articles on U2AF59    1. performed mRNA profiling for splicing in the U2AF(59) (prp2.1) temperature-sensitive mutant. Introns show a range of splicing defects in the mutant strain.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-U2AF59 antibody
 Products by Pathway  Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram
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