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anti-Ube2d2a antibody :: Rabbit anti-Human UBE2D2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS6012359 anti-Ube2d2a antibody
Unit / Price
0.2 mL  /  $550 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

UBE2D2 (Ube2d2a), Polyclonal Antibody

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 Also Known As   

UBE2D2, CT (UBE2D2, UBC4, UBC5B, UBCH4, UBCH5B, Ubiquitin-conjugating enzyme E2 D2, Ubiquitin carrier protein D2, Ubiquitin-conjugating enzyme E2(17)KB 2, Ubiquitin-conjugating enzyme E2-17kD 2, Ubiquitin-protein ligase D2)

 Product Synonym Names    Anti -UBE2D2, CT (UBE2D2, UBC4, UBC5B, UBCH4, UBCH5B, Ubiquitin-conjugating enzyme E2 D2, Ubiquitin carrier protein D2, Ubiquitin-conjugating enzyme E2(17)KB 2, Ubiquitin-conjugating enzyme E2-17kD 2, Ubiquitin-protein ligase D2)
 Product Gene Name   

anti-Ube2d2a antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 18; NC_000084.6 (35771559..35807172). Location: 18 B2; 18
 3D Structure    ModBase 3D Structure for P62838
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    Human
 Purity/Purification    Affinity Purified
Purified by Protein A affinity chromatography.
 Form/Format    Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
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 Immunogen    UBE2D2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-140 amino acids from the C-terminal region of human UBE2D2.
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 Preparation and Storage    May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
 Other Notes    Small volumes of anti-Ube2d2a antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-Ube2d2a antibody

   The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.
 Product Categories/Family for anti-Ube2d2a antibody    Antibodies; Abs to Ubiquitin Ligases
 Applications Tested/Suitable for anti-Ube2d2a antibody   

ELISA (EL/EIA), Western Blot (WB)

 Application Notes for anti-Ube2d2a antibody    Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
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NCBI/Uniprot data below describe general gene information for Ube2d2a. It may not necessarily be applicable to this product.
 NCBI GI #    9910600
 NCBI GeneID    56550
 NCBI Accession #    NP_064296.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_019912.2 [Other Products]
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 UniProt Primary Accession #    P62838 [Other Products]
 UniProt Secondary Accession #    P51669 [Other Products]
 UniProt Related Accession #    P62838 [Other Products]
 Molecular Weight    16,735 Da [Similar Products]
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 NCBI Official Full Name    ubiquitin-conjugating enzyme E2 D2
 NCBI Official Synonym Full Names    ubiquitin-conjugating enzyme E2D 2A
 NCBI Official Symbol    Ube2d2a [Similar Products]
 NCBI Official Synonym Symbols   
ubc4; Ubc2e; Ube2d2; 1500034D03Rik
[Similar Products]
 NCBI Protein Information    ubiquitin-conjugating enzyme E2 D2; E2(17)KB 2; ubiquitin-protein ligase D2; ubiquitin carrier protein D2; ubiquitin conjugating enzyme 2e; ubiquitin-conjugating enzyme E2D 2; ubiquitin-conjugating enzyme E2(17)KB 2; ubiquitin-conjugating enzyme E2-17 kDa 2
 UniProt Protein Name    Ubiquitin-conjugating enzyme E2 D2
 UniProt Synonym Protein Names   
Ubiquitin carrier protein D2; Ubiquitin-conjugating enzyme E2(17)KB 2; Ubiquitin-conjugating enzyme E2-17 kDa 2; Ubiquitin-protein ligase D2
 UniProt Gene Name    Ube2d2 [Similar Products]
 UniProt Synonym Gene Names    Ubc4; Ubch4; Ubch5b; Ube2d2a [Similar Products]
 UniProt Entry Name    UB2D2_MOUSE
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 UniProt Comments for Ube2d2a    UBE2D2: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP- induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by DDX58/RIG-I in response to viral infection. Essential for viral activation of IRF3. Belongs to the ubiquitin-conjugating enzyme family.

Protein type: EC; Ligase; Ubiquitin conjugating system; Ubiquitin ligase

Cellular Component: protein complex; ubiquitin ligase complex

Molecular Function: protein binding; nucleotide binding; ubiquitin-protein ligase activity; ATP binding; ligase activity

Biological Process: protein polyubiquitination; protein ubiquitination
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-Ube2d2a antibody
 Products by Pathway  Pathway Diagram
 Activated TLR4 Signalling Pathway antibodies  Activated TLR4 Signalling Pathway Diagram
 Cellular Response To Hypoxia Pathway antibodies  Cellular Response To Hypoxia Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 IKK Complex Recruitment Mediated By RIP1 Pathway antibodies  IKK Complex Recruitment Mediated By RIP1 Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 MyD88-independent Cascade Pathway antibodies  MyD88-independent Cascade Pathway Diagram
 Oxygen-dependent Proline Hydroxylation Of Hypoxia-inducible Factor Alpha Pathway antibodies  Oxygen-dependent Proline Hydroxylation Of Hypoxia-inducible Factor Alpha Pathway Diagram
 Proteasome Degradation Pathway antibodies  Proteasome Degradation Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
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