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anti-UBE2L6 antibody :: Rabbit UBE2L6 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9133700
Western Blot (WB)
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.1 mL  /  $305 +1 FREE 8GB USB
0.2 mL  /  $460 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

UBE2L6, Polyclonal Antibody

★Popular Item★
 Also Known As   

UBE2L6 Polyclonal Antibody

 Product Synonym Names    RIG-B; UBCH8
 Product Gene Name   

anti-UBE2L6 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    AFNLRISFPP EYPFKPPMIK FTTKIYHPNV DENGQICLPI ISSENWKPCT KTCQVLEALN VLVNRPNIRE PLRMDLADLL TQNPELFRKN AEEFTLRFGV DRPS
 OMIM    AJ243268
 3D Structure
   ModBase 3D Structure for O14933
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Affinity Purification
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 Immunogen    A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminues of human UBE2l6 (NP_004214.1).
 Calculated MW    10kDa/17kDa
 Observed MW    18kDa
 Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3
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 Preparation and Storage    Store at -20C. Avoid freeze / thaw cycles.
 Other Notes    Small volumes of anti-UBE2L6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-UBE2L6 antibody

   The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
 Product Categories/Family for anti-UBE2L6 antibody    Polyclonal Antibodies
 Applications Tested/Suitable for anti-UBE2L6 antibody   

Western Blot (WB)

 Application Notes for anti-UBE2L6 antibody    WB: 1:500 - 1:2000
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 Western Blot (WB) of anti-UBE2L6 antibody    Western blot analysis of extracts of various cell lines, using UBE2L6 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 5s.
anti-UBE2L6 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for UBE2L6. It may not necessarily be applicable to this product.
 NCBI GI #    4759282
 NCBI GeneID    9246
 NCBI Accession #    NP_004214.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_004223.4 [Other Products]
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 UniProt Primary Accession #    O14933 [Other Products]
 UniProt Secondary Accession #    Q8N5D8; Q9UEZ0; A6NDM6; A8MY53 [Other Products]
 UniProt Related Accession #    O14933 [Other Products]
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 NCBI Official Full Name    ubiquitin/ISG15-conjugating enzyme E2 L6 isoform 1
 NCBI Official Synonym Full Names    ubiquitin conjugating enzyme E2 L6
 NCBI Official Symbol    UBE2L6 [Similar Products]
 NCBI Official Synonym Symbols   
RIG-B; UBCH8
[Similar Products]
 NCBI Protein Information    ubiquitin/ISG15-conjugating enzyme E2 L6
 UniProt Protein Name    Ubiquitin/ISG15-conjugating enzyme E2 L6
 UniProt Synonym Protein Names   
E2 ubiquitin-conjugating enzyme L6; Retinoic acid-induced gene B protein; RIG-B; UbcH8; Ubiquitin carrier protein L6; Ubiquitin-protein ligase L6
 Protein Family    Ubiquitin/ISG15-conjugating enzyme
 UniProt Gene Name    UBE2L6 [Similar Products]
 UniProt Synonym Gene Names    UBCH8; RIG-B [Similar Products]
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 NCBI Summary for UBE2L6    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2011]
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 UniProt Comments for UBE2L6    Catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Promotes ubiquitination and subsequent proteasomal degradation of FLT3.
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 Research Articles on UBE2L6    1. Depletion of either ISG15 or UBE2L6/UBCH8 resulted in enhanced endogenous autophagic flux.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-UBE2L6 antibodyPathways associated with anti-UBE2L6 antibody
 Reference Product  PubMed Publications
 ISG15 antibody  >13 publications with UBE2L6 and ISG15
 STAT1 antibody  >1 publications with UBE2L6 and STAT1
 HERC5 antibody  >1 publications with UBE2L6 and HERC5
 DDX58 antibody  >1 publications with UBE2L6 and DDX58
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Antigen Processing: Ubiquitination & Proteasome Degradation Pathway antibodies  Antigen Processing: Ubiquitination & Proteasome Degradation Pathway Diagram
 Antiviral Mechanism By IFN-stimulated Genes Pathway antibodies  Antiviral Mechanism By IFN-stimulated Genes Pathway Diagram
 Class I MHC Mediated Antigen Processing & Presentation Pathway antibodies  Class I MHC Mediated Antigen Processing & Presentation Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 ISG15 Antiviral Mechanism Pathway antibodies  ISG15 Antiviral Mechanism Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Interferon Signaling Pathway antibodies  Interferon Signaling Pathway Diagram
 Negative Regulators Of RIG-I/MDA5 Signaling Pathway antibodies  Negative Regulators Of RIG-I/MDA5 Signaling Pathway Diagram
Diseases associated with anti-UBE2L6 antibodyOrgans/Tissues associated with anti-UBE2L6 antibody
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >3 publications with UBE2L6 and Breast Neoplasms
 Inflammation Antibodies  >3 publications with UBE2L6 and Inflammation
 Influenza, Human Antibodies  >2 publications with UBE2L6 and Influenza, Human
 Poisoning Antibodies  >1 publications with UBE2L6 and Poisoning
 Brain Diseases Antibodies  >1 publications with UBE2L6 and Brain Diseases
 Hypertrophy Antibodies  >1 publications with UBE2L6 and Hypertrophy
 Hyperplasia Antibodies  >1 publications with UBE2L6 and Hyperplasia
 Weight Loss Antibodies  >1 publications with UBE2L6 and Weight Loss
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >6 publications with UBE2L6 and Blood
 Lung Antibodies  >2 publications with UBE2L6 and Lung
 Bone Antibodies  >1 publications with UBE2L6 and Bone
 Lymph Node Antibodies  >1 publications with UBE2L6 and Lymph Node
 Connective Tissue Antibodies  >1 publications with UBE2L6 and Connective Tissue
 Kidney Antibodies  >1 publications with UBE2L6 and Kidney
 Lymph Antibodies  >1 publications with UBE2L6 and Lymph
 Embryonic Tissue Antibodies  >1 publications with UBE2L6 and Embryonic Tissue
 Intestine Antibodies  >1 publications with UBE2L6 and Intestine
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