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anti-UBA52 antibody :: Rabbit UBIQUITIN Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS222710 anti-UBA52 antibody
Unit / Price
1 mL  /  $365 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

UBIQUITIN (UBA52), Polyclonal Antibody

 Also Known As   

RABBIT ANTI BOVINE UBIQUITIN

 Product Gene Name   

anti-UBA52 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
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 Specificity    This item is specific for bovine ubiquitin.
 Form/Format    Purified
Ig fraction - lyophilised
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 Reconstitution    Reconstitute with 1 ml of sterile distilled water. For long term storage the addition of a preservative is recommended.
Preparation
 Immunogen    Purified bovine ubiquitin
Buffer Solution
 Target Species    Bovine
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 Preparation and Storage    Store at -20 degree C only. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 12 months from date of reconstitution.
 Other Notes    Small volumes of anti-UBA52 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-UBA52 antibody

   MBS222710 is specific for bovine ubiquitin.
 Applications Tested/Suitable for anti-UBA52 antibody   

Immunodiffusion (ID), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for UBA52. It may not necessarily be applicable to this product.
 NCBI GI #    51703340
 NCBI GeneID    615199
 NCBI Accession #    P62990.1 [Other Products]
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 UniProt Secondary Accession #    O97577; P02248; P02249; P02250; P62990; P80169; Q01235; Q24K23; Q28169; Q28170; Q29120 [Other Products]
 UniProt Related Accession #    P63048 [Other Products]
 Molecular Weight    14,728 Da [Similar Products]
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 NCBI Official Synonym Full Names    ubiquitin A-52 residue ribosomal protein fusion product 1<
 NCBI Official Symbol    UBA52 [Similar Products]
 NCBI Official Synonym Symbols   
UBB; UBC; RPS27A
[Similar Products]
 NCBI Protein Information    ubiquitin-60S ribosomal protein L40
 UniProt Protein Name    Ubiquitin-60S ribosomal protein L40
 UniProt Synonym Protein Names   
Ubiquitin A-52 residue ribosomal protein fusion product 1Cleaved into the following 2 chains:Ubiquitin; 60S ribosomal protein L40Alternative name(s):CEP52
 Protein Family    Ubiquitin
 UniProt Gene Name    UBA52 [Similar Products]
 UniProt Synonym Gene Names    UBCEP2 [Similar Products]
 UniProt Entry Name    RL40_BOVIN
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 UniProt Comments for UBA52    ubiquitin: a peptide 76 amino acids in length that can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Ubiquitin is encoded by 4 different genes. UBA52 and RPS27A genes code for a single copy of ubiquitin fused to the ribosomal proteins L40 and S27a, respectively. UBB and UBC genes code for a polyubiquitin precursor with exact head to tail repeats, the number of repeats differ between species and strains. Only the 76 amino acids of monoubiquitin product are shown in this entry. At the protein level, it is not possible to determine which of the four genes a given ubiquitin chain was derived from. Hundreds of ubiquitin ligases and hydrolases have been identified, implicating ubiquitin as a major regulatory element in many crucial cellular systems. It can be covalently bound to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.

Protein type: Ubiquitin-like modifier
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-UBA52 antibodyDiseases associated with anti-UBA52 antibody
 Products by Pathway  Pathway Diagram
 AMER1 Mutants Destabilize The Destruction Complex Pathway antibodies  AMER1 Mutants Destabilize The Destruction Complex Pathway Diagram
 APC Truncation Mutants Are Not K63 Polyubiquitinated Pathway antibodies  APC Truncation Mutants Are Not K63 Polyubiquitinated Pathway Diagram
 APC Truncation Mutants Have Impaired AXIN Binding Pathway antibodies  APC Truncation Mutants Have Impaired AXIN Binding Pathway Diagram
 APC-Cdc20 Mediated Degradation Of Nek2A Pathway antibodies  APC-Cdc20 Mediated Degradation Of Nek2A Pathway Diagram
 APC/C-mediated Degradation Of Cell Cycle Proteins Pathway antibodies  APC/C-mediated Degradation Of Cell Cycle Proteins Pathway Diagram
 APC/C:Cdc20 Mediated Degradation Of Cyclin B Pathway antibodies  APC/C:Cdc20 Mediated Degradation Of Cyclin B Pathway Diagram
 APC/C:Cdc20 Mediated Degradation Of Securin Pathway antibodies  APC/C:Cdc20 Mediated Degradation Of Securin Pathway Diagram
 APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway antibodies  APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway Diagram
 APC/C:Cdh1 Mediated Degradation Of Cdc20 And Other APC/C:Cdh1 Targeted Proteins In Late Mitosis/early G1 Pathway antibodies  APC/C:Cdh1 Mediated Degradation Of Cdc20 And Other APC/C:Cdh1 Targeted Proteins In Late Mitosis/early G1 Pathway Diagram
 APC:Cdc20 Mediated Degradation Of Cell Cycle Proteins Prior To Satisfation Of The Cell Cycle Checkpoint Pathway antibodies  APC:Cdc20 Mediated Degradation Of Cell Cycle Proteins Prior To Satisfation Of The Cell Cycle Checkpoint Pathway Diagram
 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >4 publications with UBA52 and Kidney Diseases
 Disease Models, Animal Antibodies  >2 publications with UBA52 and Disease Models, Animal
 Fibrosis Antibodies  >1 publications with UBA52 and Fibrosis
 Proteinuria Antibodies  >1 publications with UBA52 and Proteinuria
 Cell Transformation, Neoplastic Antibodies  >1 publications with UBA52 and Cell Transformation, Neoplastic
 Nervous System Diseases Antibodies  >1 publications with UBA52 and Nervous System Diseases
Organs/Tissues associated with anti-UBA52 antibody
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >3 publications with UBA52 and Kidney
 Uterus Antibodies  >2 publications with UBA52 and Uterus
 Brain Antibodies  >2 publications with UBA52 and Brain
 Liver Antibodies  >2 publications with UBA52 and Liver
 Blood Antibodies  >1 publications with UBA52 and Blood
 Lung Antibodies  >1 publications with UBA52 and Lung
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