Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow UCP3 rightarrow Polyclonal UCP3  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Low affinity immunoglobulin gamma Fc region receptor III-B (... ELISA Kit
 • Platelet Factor 4 (PF4) ELISA Kit
 • Vanillin 4-O- beta-D-Glucoside Biochemical
 • Collagen Type IV, 7S Domain (COL4A3) Antibody
 • Chorionic Gonadotropin beta subunit (hCG-beta) Antibody
 • Acrp30 (ADIPOQ) Recombinant Protein
 • HIV-1 p24 Antibody
 • Plasmodium vivax Antibody
 • Glutathione Peroxidase (GSH-PX) ELISA Kit
 • Netrin 1 (Ntn1) Recombinant Protein
 • HDAC4 Antibody
 • LP-a ELISA Kit
 • LUTEINIZING HORMONE RELEASING HORMONE RECEPTOR (GNRHR) Antibody
 • GRIN2A ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-UCP3 antibody :: UCP3 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS8241764
Western Blot (WB)
Unit / Price
0.03 mL  /  $155 +1 FREE 8GB USB
0.1 mL  /  $220 +1 FREE 8GB USB
0.2 mL  /  $295 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

UCP3, Polyclonal Antibody

★Popular Item★
 Also Known As   

Anti-UCP3 Antibody

 Product Synonym Names    SLC25A9; Mitochondrial uncoupling protein 3; UCP 3; Solute carrier family 25 member 9
 Product Gene Name   

anti-UCP3 antibody

[Similar Products]
 Antibody/Peptide Pairs    UCP3 peptide (MBS8243922) is used for blocking the activity of UCP3 antibody (MBS8241764)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    601665
 3D Structure    ModBase 3D Structure for P55916
Section Bar
 Clonality    Polyclonal
 Species Reactivity    Human, Mouse, Rat, Dog, Pig
Section Bar
 Specificity    Recognizes endogenous levels of UCP3 protein.
 Purity/Purification    The antibody was purified by immunogen affinity chromatography.
 Form/Format    Liquid in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3, 30% Glycerol, and 0.01% Sodium Azide.
Section Bar
 Source    Rabbit
 Immunogen    KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human UCP3. The exact sequence is proprietary.
Section Bar
 Preparation and Storage    Shipped at 4C. Upon delivery aliquot and store at -20C for one year. Avoid freeze/thaw cycles.
 Other Notes    Small volumes of anti-UCP3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for anti-UCP3 antibody

   Rabbit polyclonal antibody to UCP3
 Applications Tested/Suitable for anti-UCP3 antibody   

Western Blot (WB)

 Application Notes for anti-UCP3 antibody    Western Blot: (1/500 - 1/1000)
Section Bar
 Western Blot (WB) of anti-UCP3 antibody    Western blot analysis of UCP3 expression in L929 (A), rat kidney (B) whole cell lysates.
anti-UCP3 antibody Western Blot (WB) (WB) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for UCP3. It may not necessarily be applicable to this product.
 NCBI GI #    2497983
 NCBI GeneID    7352
 NCBI Accession #    P55916.1 [Other Products]
Section Bar
 UniProt Primary Accession #    P55916 [Other Products]
 UniProt Secondary Accession #    O60475; Q96HL3 [Other Products]
 UniProt Related Accession #    P55916 [Other Products]
Table BarTOPTable Bar
 NCBI Official Full Name    Mitochondrial uncoupling protein 3
 NCBI Official Synonym Full Names    uncoupling protein 3 (mitochondrial, proton carrier)
 NCBI Official Symbol    UCP3 [Similar Products]
 NCBI Official Synonym Symbols   
SLC25A9
[Similar Products]
 NCBI Protein Information    mitochondrial uncoupling protein 3
 UniProt Protein Name    Mitochondrial uncoupling protein 3
 UniProt Synonym Protein Names   
Solute carrier family 25 member 9
 Protein Family    UBA domain-containing protein
 UniProt Gene Name    UCP3 [Similar Products]
 UniProt Synonym Gene Names    SLC25A9; UCP 3 [Similar Products]
 UniProt Entry Name    UCP3_HUMAN
Section Bar
 NCBI Summary for UCP3    Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. The different UCPs have tissue-specific expression; this gene is primarily expressed in skeletal muscle. This gene's protein product is postulated to protect mitochondria against lipid-induced oxidative stress. Expression levels of this gene increase when fatty acid supplies to mitochondria exceed their oxidation capacity and the protein enables the export of fatty acids from mitochondria. UCPs contain the three solcar protein domains typically found in MACPs. Two splice variants have been found for this gene.[provided by RefSeq, Nov 2008]
Section Bar
 UniProt Comments for UCP3    UCP3: UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation. As a result, energy is dissipated in the form of heat. May play a role in the modulation of tissue respiratory control. Participates in thermogenesis and energy balance. Defects in UCP3 may be involved in obesity (OBESITY). It is a condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat. Belongs to the mitochondrial carrier family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial; Membrane protein, multi-pass; Membrane protein, integral; Transporter

Chromosomal Location of Human Ortholog: 11q13.4

Cellular Component: integral to membrane; mitochondrial inner membrane; mitochondrion

Molecular Function: oxidative phosphorylation uncoupler activity; protein binding; structural constituent of ribosome; transporter activity

Biological Process: aging; cellular metabolic process; cellular response to hormone stimulus; fatty acid metabolic process; lipid metabolic process; mitochondrial transport; proton transport; respiratory gaseous exchange; response to activity; response to cold; response to glucocorticoid stimulus; response to hypoxia; response to insulin stimulus; response to nutrient; response to superoxide; translation

Disease: Obesity
Table BarTOPTable Bar
 Research Articles on UCP3    1. Children with UCP-3 -55 T/T genotype had a significantly lower adjusted metabolic rate than the C allele carriers.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-UCP3 antibodyPathways associated with anti-UCP3 antibody
 Reference Product  PubMed Publications
 UCP2 antibody  >491 publications with UCP3 and UCP2
 UCP1 antibody  >342 publications with UCP3 and UCP1
 SLC2A4 antibody  >28 publications with UCP3 and SLC2A4
 INS antibody  >8 publications with UCP3 and INS
 PPARG antibody  >7 publications with UCP3 and PPARG
 PPARA antibody  >6 publications with UCP3 and PPARA
 LEP antibody  >5 publications with UCP3 and LEP
 SP3 antibody  >1 publications with UCP3 and SP3
 Products by Pathway  Pathway Diagram
 Diurnally Regulated Genes With Circadian Orthologs Pathway antibodies  Diurnally Regulated Genes With Circadian Orthologs Pathway Diagram
 Electron Transport Chain Pathway antibodies  Electron Transport Chain Pathway Diagram
 Energy Metabolism Pathway antibodies  Energy Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Mitochondrial Uncoupling Proteins Pathway antibodies  Mitochondrial Uncoupling Proteins Pathway Diagram
 Respiratory Electron Transport, ATP Synthesis By Chemiosmotic Coupling, And Heat Production By Uncoupling Proteins. Pathway antibodies  Respiratory Electron Transport, ATP Synthesis By Chemiosmotic Coupling, And Heat Production By Uncoupling Proteins. Pathway Diagram
 The Citric Acid (TCA) Cycle And Respiratory Electron Transport Pathway antibodies  The Citric Acid (TCA) Cycle And Respiratory Electron Transport Pathway Diagram
 The Fatty Acid Cycling Model Pathway antibodies  The Fatty Acid Cycling Model Pathway Diagram
 The Proton Buffering Model Pathway antibodies  The Proton Buffering Model Pathway Diagram
Diseases associated with anti-UCP3 antibodyOrgans/Tissues associated with anti-UCP3 antibody
 Disease Name  Pubmed Publications
 Obesity Antibodies  >278 publications with UCP3 and Obesity
 Diabetes Mellitus Antibodies  >91 publications with UCP3 and Diabetes Mellitus
 Insulin Resistance Antibodies  >79 publications with UCP3 and Insulin Resistance
 Weight Gain Antibodies  >62 publications with UCP3 and Weight Gain
 Diabetes Mellitus, Type 2 Antibodies  >54 publications with UCP3 and Diabetes Mellitus, Type 2
 Hyperinsulinism Antibodies  >49 publications with UCP3 and Hyperinsulinism
 Fatty Liver Antibodies  >48 publications with UCP3 and Fatty Liver
 Weight Loss Antibodies  >47 publications with UCP3 and Weight Loss
 Mitochondrial Diseases Antibodies  >45 publications with UCP3 and Mitochondrial Diseases
 Disease Models, Animal Antibodies  >40 publications with UCP3 and Disease Models, Animal
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >583 publications with UCP3 and Muscle
 Connective Tissue Antibodies  >220 publications with UCP3 and Connective Tissue
 Blood Antibodies  >203 publications with UCP3 and Blood
 Heart Antibodies  >126 publications with UCP3 and Heart
 Liver Antibodies  >93 publications with UCP3 and Liver
 Brain Antibodies  >51 publications with UCP3 and Brain
 Lung Antibodies  >19 publications with UCP3 and Lung
 Vascular Antibodies  >17 publications with UCP3 and Vascular
 Embryonic Tissue Antibodies  >6 publications with UCP3 and Embryonic Tissue
 Intestine Antibodies  >3 publications with UCP3 and Intestine
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions