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anti-UGCG antibody :: Rabbit UGCG Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9127228
Western Blot (WB)
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.1 mL  /  $305 +1 FREE 8GB USB
0.2 mL  /  $460 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

UGCG, Polyclonal Antibody

★Popular Item★
 Also Known As   

UGCG Polyclonal Antibody

 Product Synonym Names    GCS; GLCT1
 Product Gene Name   

anti-UGCG antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    602874
 3D Structure    ModBase 3D Structure for Q16739
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Affinity Purification
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 Species    Human
 Category    Primary antibody
 Immunogen    Recombinant protein of human UGCG
 Calculated Molecular Weight    44kDa
 Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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 Preparation and Storage    Store at -20 degree C. Avoid freeze / thaw cycles.
 Other Notes    Small volumes of anti-UGCG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-UGCG antibody

   Glycosphingolipids (GSLs) are a group of membrane components that contain lipid and sugar moieties. They are present in essentially all animal cells and are believed to have important roles in various cellular processes. UDP-glucose ceramide glucosyltransferase catalyzes the first glycosylation step in glycosphingolipid biosynthesis. The product, glucosylceramide, is the core structure of more than 300 GSLs. UGCG is widely expressed and transcription is upregulated during keratinocyte differentiation.
 Product Categories/Family for anti-UGCG antibody    Polyclonal
 Applications Tested/Suitable for anti-UGCG antibody   

Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-UGCG antibody    WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
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 Western Blot (WB) of anti-UGCG antibody    Western blot analysis of extracts of mouse brain, using UGCG antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 30s.
anti-UGCG antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for UGCG. It may not necessarily be applicable to this product.
 NCBI GI #    2498228
 NCBI GeneID    7357
 NCBI Accession #    Q16739.1 [Other Products]
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 UniProt Primary Accession #    Q16739 [Other Products]
 UniProt Secondary Accession #    Q5T258 [Other Products]
 UniProt Related Accession #    Q16739 [Other Products]
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 NCBI Official Full Name    Ceramide glucosyltransferase
 NCBI Official Synonym Full Names    UDP-glucose ceramide glucosyltransferase
 NCBI Official Symbol    UGCG [Similar Products]
 NCBI Official Synonym Symbols   
GCS; GLCT1
[Similar Products]
 NCBI Protein Information    ceramide glucosyltransferase; glucosylceramide synthase; UDP-glucose:N-acylsphingosine D-glucosyltransferase
 UniProt Protein Name    Ceramide glucosyltransferase
 UniProt Synonym Protein Names   
GLCT-1; Glucosylceramide synthase; GCS; UDP-glucose ceramide glucosyltransferase; UDP-glucose:N-acylsphingosine D-glucosyltransferase
 Protein Family    Ceramide glucosyltransferase
 UniProt Gene Name    UGCG [Similar Products]
 UniProt Synonym Gene Names    GCS [Similar Products]
 UniProt Entry Name    CEGT_HUMAN
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 NCBI Summary for UGCG    This gene encodes an enzyme that catalyzes the first glycosylation step in the biosynthesis of glycosphingolipids, which are membrane components containing lipid and sugar moieties. The product of this reaction is glucosylceramide, which is the core structure of many glycosphingolipids. [provided by RefSeq, Dec 2014]
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 UniProt Comments for UGCG    UGCG: Catalyzes the first glycosylation step in glycosphingolipid biosynthesis, the transfer of glucose to ceramide. May also serve as a flippase. Belongs to the glycosyltransferase 2 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transferase; EC 2.4.1.80; Lipid Metabolism - sphingolipid

Chromosomal Location of Human Ortholog: 9q31

Cellular Component: Golgi membrane; membrane; integral to membrane

Molecular Function: ceramide glucosyltransferase activity

Biological Process: epidermis development; glycosphingolipid biosynthetic process; sphingolipid metabolic process; glycosphingolipid metabolic process; glucosylceramide biosynthetic process
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 Research Articles on UGCG    1. Our data demonstrates a correlation between the expression of the GCS protein and ER-positive/HER-2 negative breast cancer
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-UGCG antibodyPathways associated with anti-UGCG antibody
 Reference Product  PubMed Publications
 GBA antibody  >2 publications with UGCG and GBA
 UGT8 antibody  >2 publications with UGCG and UGT8
 ASAH1 antibody  >1 publications with UGCG and ASAH1
 B4GALT6 antibody  >1 publications with UGCG and B4GALT6
 SMPD1 antibody  >1 publications with UGCG and SMPD1
 Products by Pathway  Pathway Diagram
 Glycosphingolipid Metabolism Pathway antibodies  Glycosphingolipid Metabolism Pathway Diagram
 IL2 Signaling Events Mediated By PI3K Pathway antibodies  IL2 Signaling Events Mediated By PI3K Pathway Diagram
 Lactosylceramide Biosynthesis Pathway antibodies  Lactosylceramide Biosynthesis Pathway Diagram
 Lactosylceramide Biosynthesis Pathway antibodies  Lactosylceramide Biosynthesis Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Sphingolipid Metabolism Pathway antibodies  Sphingolipid Metabolism Pathway Diagram
 Sphingolipid Metabolism Pathway antibodies  Sphingolipid Metabolism Pathway Diagram
 Sphingolipid Metabolism Pathway antibodies  Sphingolipid Metabolism Pathway Diagram
Diseases associated with anti-UGCG antibodyOrgans/Tissues associated with anti-UGCG antibody
 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >4 publications with UGCG and Fatty Liver
 Kidney Diseases Antibodies  >4 publications with UGCG and Kidney Diseases
 Nerve Degeneration Antibodies  >2 publications with UGCG and Nerve Degeneration
 Carcinoma Antibodies  >2 publications with UGCG and Carcinoma
 Liver Diseases Antibodies  >2 publications with UGCG and Liver Diseases
 Inflammation Antibodies  >2 publications with UGCG and Inflammation
 Disease Models, Animal Antibodies  >2 publications with UGCG and Disease Models, Animal
 Neural Tube Defects Antibodies  >1 publications with UGCG and Neural Tube Defects
 Weight Loss Antibodies  >1 publications with UGCG and Weight Loss
 Prenatal Exposure Delayed Effects Antibodies  >1 publications with UGCG and Prenatal Exposure Delayed Effects
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >11 publications with UGCG and Brain
 Liver Antibodies  >5 publications with UGCG and Liver
 Blood Antibodies  >4 publications with UGCG and Blood
 Kidney Antibodies  >4 publications with UGCG and Kidney
 Embryonic Tissue Antibodies  >3 publications with UGCG and Embryonic Tissue
 Skin Antibodies  >3 publications with UGCG and Skin
 Intestine Antibodies  >2 publications with UGCG and Intestine
 Heart Antibodies  >1 publications with UGCG and Heart
 Mouth Antibodies  >1 publications with UGCG and Mouth
 Ovary Antibodies  >1 publications with UGCG and Ovary
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