NP_001121646.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
61,438 Da
NCBI Official Full Name
2-hydroxyacylsphingosine 1-beta-galactosyltransferase
NCBI Official Synonym Full Names
UDP glycosyltransferase 8
NCBI Official Synonym Symbols
NCBI Protein Information
2-hydroxyacylsphingosine 1-beta-galactosyltransferase; cerebroside synthase; ceramide UDP-galactosyltransferase; uridine diphosphate glycosyltransferase 8; UDP-galactose ceramide galactosyltransferase; UDP-galactose-ceramide galactosyltransferase
UniProt Protein Name
2-hydroxyacylsphingosine 1-beta-galactosyltransferase
UniProt Synonym Protein Names
Ceramide UDP-galactosyltransferase; Cerebroside synthase; UDP-galactose-ceramide galactosyltransferase
UniProt Synonym Gene Names
UniProt Entry Name
CGT_HUMAN
NCBI Summary for UGT8
The protein encoded by this gene belongs to the UDP-glycosyltransferase family. It catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central and peripheral nervous systems. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2011]
UniProt Comments for UGT8
UGT8: Catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system. Belongs to the UDP-glycosyltransferase family.
Protein type: Lipid Metabolism - sphingolipid; Transferase; Membrane protein, integral; EC 2.4.1.45
Chromosomal Location of Human Ortholog: 4q26
Cellular Component: intracellular membrane-bound organelle; integral to membrane
Molecular Function: UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity; glucuronosyltransferase activity; 2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity
Biological Process: central nervous system development; flavonoid biosynthetic process; galactosylceramide biosynthetic process; axon cargo transport; cytoskeleton organization and biogenesis; neurite morphogenesis; cellular response to hormone stimulus; peripheral nervous system development; paranodal junction assembly
Research Articles on UGT8
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Products associated with anti-UGT8 antibody
Pathways associated with anti-UGT8 antibody
Diseases associated with anti-UGT8 antibody
Organs/Tissues associated with anti-UGT8 antibody
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