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anti-UQCRC2 antibody :: Chicken Ubiquinol Cytochrome C Reductase Core Protein II Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS617525 anti-UQCRC2 antibody
Unit / Price
0.05 mg  /  $540 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2), Polyclonal Antibody

 Also Known As   

Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2)

 Product Synonym Names    Anti -Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2)
 Product Gene Name   

anti-UQCRC2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 16; NC_000016.9 (21964609..21994668). Location: 16p12
 OMIM    191329
 3D Structure    ModBase 3D Structure for P22695
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 Clonality    Polyclonal
 Isotype    IgY
 Host    Chicken
 Species Reactivity    Human, Mouse, Rat
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 Specificity    Recognizes human UQCRC2. Species Crossreactivity: Mouse and rat.
 Purity/Purification    Affinity Purified
Purified by immunoaffinity chromatography.
 Form/Format    Supplied as a liquid in PBS, pH 7.2. No preservative added. Glycerol free.
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 Immunogen    Synthetic peptide corresponding to aa231-453
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 Preparation and Storage    May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of anti-UQCRC2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-UQCRC2 antibody

   UQCRC2 is a component of the ubiquinol-cytochrome c reductase complex (complex III), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex.
 Product Categories/Family for anti-UQCRC2 antibody    Antibodies; Abs to Enzymes, Cytochrome
 Applications Tested/Suitable for anti-UQCRC2 antibody   

ELISA (EL/EIA), Western Blot (WB)

 Application Notes for anti-UQCRC2 antibody    Suitable for use in ELISA and Western Blot.
Dilution: Western Blot: 1:1000-1:2000
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NCBI/Uniprot data below describe general gene information for UQCRC2. It may not necessarily be applicable to this product.
 NCBI GI #    13111931
 NCBI GeneID    7385
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 UniProt Primary Accession #    P22695 [Other Products]
 UniProt Secondary Accession #    Q9BQ05; B3KSN4 [Other Products]
 UniProt Related Accession #    P22695 [Other Products]
 Molecular Weight    48,443 Da [Similar Products]
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 NCBI Official Full Name    Ubiquinol-cytochrome c reductase core protein II
 NCBI Official Synonym Full Names    ubiquinol-cytochrome c reductase core protein II
 NCBI Official Symbol    UQCRC2 [Similar Products]
 NCBI Official Synonym Symbols   
QCR2; UQCR2
[Similar Products]
 NCBI Protein Information    cytochrome b-c1 complex subunit 2, mitochondrial; core protein II; OTTHUMP00000162338; complex III subunit 2; ubiquinol-cytochrome-c reductase complex core protein 2
 UniProt Protein Name    Cytochrome b-c1 complex subunit 2, mitochondrial
 UniProt Synonym Protein Names   
Complex III subunit 2; Core protein II; Ubiquinol-cytochrome-c reductase complex core protein 2
 UniProt Gene Name    UQCRC2 [Similar Products]
 UniProt Entry Name    QCR2_HUMAN
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 NCBI Summary for UQCRC2    The protein encoded by this gene is located in the mitochondrion, where it is part of the ubiquinol-cytochrome c reductase complex (also known as complex III). This complex constitutes a part of the mitochondrial respiratory chain. Defects in this gene are a cause of mitochondrial complex III deficiency nuclear type 5. [provided by RefSeq, Jul 2015]
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 UniProt Comments for UQCRC2    UQCRC2: This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex. Belongs to the peptidase M16 family. UQCRC2/QCR2 subfamily.

Protein type: EC 1.10.2.2; Energy Metabolism - oxidative phosphorylation; Oxidoreductase; Mitochondrial

Chromosomal Location of Human Ortholog: 16p12

Cellular Component: mitochondrion; mitochondrial inner membrane; mitochondrial respiratory chain complex III

Molecular Function: protein binding; metal ion binding; metalloendopeptidase activity; protein complex binding

Biological Process: cellular metabolic process; aerobic respiration; proteolysis; oxidative phosphorylation

Disease: Mitochondrial Complex Iii Deficiency, Nuclear Type 5
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 Research Articles on UQCRC2    1. Observational study of gene-disease association. (HuGE Navigator)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-UQCRC2 antibodyPathways associated with anti-UQCRC2 antibody
 Reference Product  PubMed Publications
 UQCRC1 antibody  >3 publications with UQCRC2 and UQCRC1
 Products by Pathway  Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Cardiac Muscle Contraction Pathway antibodies  Cardiac Muscle Contraction Pathway Diagram
 Cardiac Muscle Contraction Pathway antibodies  Cardiac Muscle Contraction Pathway Diagram
 Electron Transport Chain Pathway antibodies  Electron Transport Chain Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Oxidative Phosphorylation Pathway antibodies  Oxidative Phosphorylation Pathway Diagram
 Oxidative Phosphorylation Pathway antibodies  Oxidative Phosphorylation Pathway Diagram
Diseases associated with anti-UQCRC2 antibodyOrgans/Tissues associated with anti-UQCRC2 antibody
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >1 publications with UQCRC2 and Breast Neoplasms
 Inflammation Antibodies  >1 publications with UQCRC2 and Inflammation
 Carcinoma Antibodies  >1 publications with UQCRC2 and Carcinoma
 Neurodegenerative Diseases Antibodies  >1 publications with UQCRC2 and Neurodegenerative Diseases
 Infertility, Male Antibodies  >1 publications with UQCRC2 and Infertility, Male
 Genetic Diseases, Inborn Antibodies  >1 publications with UQCRC2 and Genetic Diseases, Inborn
 Organ/Tissue Name  Pubmed Publications
 Epididymis Antibodies  >1 publications with UQCRC2 and Epididymis
 Spinal Cord Antibodies  >1 publications with UQCRC2 and Spinal Cord
 Nerve Antibodies  >1 publications with UQCRC2 and Nerve
 Muscle Antibodies  >1 publications with UQCRC2 and Muscle
 Lung Antibodies  >1 publications with UQCRC2 and Lung
 Heart Antibodies  >1 publications with UQCRC2 and Heart
 Brain Antibodies  >1 publications with UQCRC2 and Brain
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