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anti-ATP6V1E1 antibody :: Rabbit anti-Human V-type proton ATPase subunit E 1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS715499
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

V-type proton ATPase subunit E 1 (ATP6V1E1), Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-human V-type proton ATPase subunit E 1 polyclonal Antibody

 Product Gene Name   

anti-ATP6V1E1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    108746
 3D Structure    ModBase 3D Structure for P36543
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Caprylic Acid Ammonium Sulfate Precipitation Purified
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 Storage Buffer    Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Conjugate    Non-conjugated
 Immunogen    Recombinant human V-type proton ATPase subunit E 1 protein
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-21218 / sc-20946
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-ATP6V1E1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-ATP6V1E1 antibody

   Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
 Applications Tested/Suitable for anti-ATP6V1E1 antibody   

ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)

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 Western Blot (WB) of anti-ATP6V1E1 antibody    Western blot
V-type proton ATPase subunit E 1 Antibody at 2ug/ml+293T whole cell lysate
Secondary
Goat polyclonal to Rabbit IgG at 1/15000 dilution
Predicted band size: 27,24,23 kDa
Observed band size: 36 kDa

anti-ATP6V1E1 antibody Western Blot (WB) (WB) image
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 Immunofluorescence (IF) of anti-ATP6V1E1 antibody    Immunofluorescent analysis of Hela cells using MBS715499 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-ATP6V1E1 antibody Immunofluorescence (IF) image
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NCBI/Uniprot data below describe general gene information for ATP6V1E1. It may not necessarily be applicable to this product.
 NCBI GI #    87159816
 NCBI GeneID    529
 NCBI Accession #    NP_001034455.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001039366.1 [Other Products]
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 UniProt Primary Accession #    P36543 [Other Products]
 UniProt Secondary Accession #    A8MUE4; A8MUN4 [Other Products]
 UniProt Related Accession #    P36543 [Other Products]
 Molecular Weight    22,706 Da [Similar Products]
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 NCBI Official Full Name    V-type proton ATPase subunit E 1 isoform b
 NCBI Official Synonym Full Names    ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1
 NCBI Official Symbol    ATP6V1E1 [Similar Products]
 NCBI Official Synonym Symbols   
P31; Vma4; ATP6E; ATP6E2; ATP6V1E
[Similar Products]
 NCBI Protein Information    V-type proton ATPase subunit E 1
 UniProt Protein Name    V-type proton ATPase subunit E 1
 UniProt Synonym Protein Names   
V-ATPase 31 kDa subunit; p31; Vacuolar proton pump subunit E 1
 Protein Family    V-type proton ATPase
 UniProt Gene Name    ATP6V1E1 [Similar Products]
 UniProt Synonym Gene Names    ATP6E; ATP6E2; V-ATPase subunit E 1; p31 [Similar Products]
 UniProt Entry Name    VATE1_HUMAN
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 NCBI Summary for ATP6V1E1    This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain E subunit isoforms. Pseudogenes for this gene have been found in the genome. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ATP6V1E1    ATP6V1E1: Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. Belongs to the V-ATPase E subunit family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Hydrolase; Mitochondrial; Energy Metabolism - oxidative phosphorylation; EC 3.6.3.14

Chromosomal Location of Human Ortholog: 22q11.1

Cellular Component: apical plasma membrane; cytosol; endosome; lysosomal membrane; microvillus; mitochondrion; proton-transporting two-sector ATPase complex

Molecular Function: ATPase binding; hydrogen ion transporting ATPase activity, rotational mechanism; hydrogen-exporting ATPase activity, phosphorylative mechanism; protein binding

Biological Process: ATP hydrolysis coupled proton transport; cell redox homeostasis; cellular iron ion homeostasis; insulin receptor signaling pathway; metabolic process; proton transport; transferrin transport; transmembrane transport
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 Research Articles on ATP6V1E1    1. Low-grade PanIN lesions with typical columnar morphology displayed diffuse labeling of the V1E subunit. In advanced lesions it was found along the basolateral membranes.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ATP6V1E1 antibodyPathways associated with anti-ATP6V1E1 antibody
 Reference Product  PubMed Publications
 ATP6V1B2 antibody  >2 publications with ATP6V1E1 and ATP6V1B2
 ATP6V0D2 antibody  >1 publications with ATP6V1E1 and ATP6V0D2
 ATP6V0D1 antibody  >1 publications with ATP6V1E1 and ATP6V0D1
 ATP6V1C1 antibody  >1 publications with ATP6V1E1 and ATP6V1C1
 ATP6V1A antibody  >1 publications with ATP6V1E1 and ATP6V1A
 ATP6V1F antibody  >1 publications with ATP6V1E1 and ATP6V1F
 ATP6V1H antibody  >1 publications with ATP6V1E1 and ATP6V1H
 ATP6V1B1 antibody  >1 publications with ATP6V1E1 and ATP6V1B1
 Products by Pathway  Pathway Diagram
 Collecting Duct Acid Secretion Pathway antibodies  Collecting Duct Acid Secretion Pathway Diagram
 Collecting Duct Acid Secretion Pathway antibodies  Collecting Duct Acid Secretion Pathway Diagram
 Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway antibodies  Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway Diagram
 Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway antibodies  Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Insulin Receptor Recycling Pathway antibodies  Insulin Receptor Recycling Pathway Diagram
 Ion Channel Transport Pathway antibodies  Ion Channel Transport Pathway Diagram
 Iron Uptake And Transport Pathway antibodies  Iron Uptake And Transport Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Oxidative Phosphorylation Pathway antibodies  Oxidative Phosphorylation Pathway Diagram
Organs/Tissues associated with anti-ATP6V1E1 antibody
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >2 publications with ATP6V1E1 and Eye
 Nerve Antibodies  >2 publications with ATP6V1E1 and Nerve
 Embryonic Tissue Antibodies  >1 publications with ATP6V1E1 and Embryonic Tissue
 Heart Antibodies  >1 publications with ATP6V1E1 and Heart
 Brain Antibodies  >1 publications with ATP6V1E1 and Brain
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