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anti-VAMP2 antibody :: Rabbit VAMP2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS126553
Western Blot (WB)
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.1 mL  /  $305 +1 FREE 8GB USB
0.2 mL  /  $460 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

VAMP2, Polyclonal Antibody

★Popular Item★
 Also Known As   

VAMP2 Polyclonal Antibody

 Product Synonym Names    VAMP2; FLJ11460; SYB2; VAMP-2
 Product Gene Name   

anti-VAMP2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    185881
 3D Structure    ModBase 3D Structure for P63027
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Affinity Purification
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 Source    Rabbit
 Immunogen    Recombinant protein of human VAMP2
 Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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 Preparation and Storage    Store at -20C. Avoid freeze / thaw cycles.
 Other Notes    Small volumes of anti-VAMP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-VAMP2 antibody

   The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25- kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG.
 Product Categories/Family for anti-VAMP2 antibody    Polyclonal
 Applications Tested/Suitable for anti-VAMP2 antibody   

Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-VAMP2 antibody    WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
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 Western Blot (WB) of anti-VAMP2 antibody    Western blot analysis of extracts of various cell lines, using VAMP2 antibody at 1:3000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 10s.
anti-VAMP2 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for VAMP2. It may not necessarily be applicable to this product.
 NCBI GI #    288558837
 NCBI GeneID    6844
 NCBI Accession #    P63027.3 [Other Products]
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 UniProt Primary Accession #    P63027 [Other Products]
 UniProt Secondary Accession #    P19065; Q9BUC2 [Other Products]
 UniProt Related Accession #    P63027 [Other Products]
 Molecular Weight    13kDa
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 NCBI Official Full Name    Vesicle-associated membrane protein 2
 NCBI Official Synonym Full Names    vesicle-associated membrane protein 2 (synaptobrevin 2)
 NCBI Official Symbol    VAMP2 [Similar Products]
 NCBI Official Synonym Symbols   
SYB2; VAMP-2
[Similar Products]
 NCBI Protein Information    vesicle-associated membrane protein 2; synaptobrevin 2; synaptobrevin-2; vesicle associated membrane protein 2
 UniProt Protein Name    Vesicle-associated membrane protein 2
 UniProt Synonym Protein Names   
Synaptobrevin-2
 Protein Family    Vesicle-associated membrane protein
 UniProt Gene Name    VAMP2 [Similar Products]
 UniProt Synonym Gene Names    SYB2; VAMP-2 [Similar Products]
 UniProt Entry Name    VAMP2_HUMAN
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 NCBI Summary for VAMP2    The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG. [provided by RefSeq, Jul 2008]
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 UniProt Comments for VAMP2    VAMP2: a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. Thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin.

Protein type: Motility/polarity/chemotaxis; Vesicle; Membrane protein, integral

Chromosomal Location of Human Ortholog: 17p13.1

Cellular Component: zymogen granule membrane; neuron projection; synaptic vesicle membrane; intracellular membrane-bound organelle; clathrin-coated vesicle; integral to plasma membrane; secretory granule membrane; trans-Golgi network; cytosol; secretory granule; SNARE complex; synaptic vesicle; membrane; perinuclear region of cytoplasm; plasma membrane; synapse; cytoplasmic vesicle; cell junction

Molecular Function: calmodulin binding; SNAP receptor activity; protein binding; SNARE binding; protein self-association; syntaxin binding; syntaxin-1 binding; phospholipid binding; calcium-dependent protein binding

Biological Process: exocytosis; natural killer cell degranulation; neurotransmitter secretion; neutrophil degranulation; pathogenesis; calcium ion-dependent exocytosis; vesicle fusion; regulation of exocytosis; vesicle-mediated transport; synaptic transmission; protein transport; synaptic vesicle exocytosis; cellular protein metabolic process; glutamate secretion; cellular response to insulin stimulus; Golgi to plasma membrane protein transport; response to glucose stimulus; energy reserve metabolic process; eosinophil degranulation; protein complex assembly; post-Golgi vesicle-mediated transport; regulation of insulin secretion
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 Research Articles on VAMP2    1. The genetic variations of VAMP2, Synaptotagmin XI might be indication of the relationship between these genes and idiopathic generalized epilepsy
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-VAMP2 antibodyPathways associated with anti-VAMP2 antibody
 Reference Product  PubMed Publications
 SNAP25 antibody  >87 publications with VAMP2 and SNAP25
 SNAP23 antibody  >41 publications with VAMP2 and SNAP23
 STX1A antibody  >32 publications with VAMP2 and STX1A
 SYT1 antibody  >14 publications with VAMP2 and SYT1
 SYP antibody  >6 publications with VAMP2 and SYP
 STXBP3 antibody  >5 publications with VAMP2 and STXBP3
 CPLX1 antibody  >2 publications with VAMP2 and CPLX1
 STX4 antibody  >2 publications with VAMP2 and STX4
 STX3 antibody  >1 publications with VAMP2 and STX3
 UNC13B antibody  >1 publications with VAMP2 and UNC13B
 Products by Pathway  Pathway Diagram
 Acetylcholine Neurotransmitter Release Cycle Pathway antibodies  Acetylcholine Neurotransmitter Release Cycle Pathway Diagram
 Clathrin Derived Vesicle Budding Pathway antibodies  Clathrin Derived Vesicle Budding Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Dopamine Neurotransmitter Release Cycle Pathway antibodies  Dopamine Neurotransmitter Release Cycle Pathway Diagram
 Effects Of Botulinum Toxin Pathway antibodies  Effects Of Botulinum Toxin Pathway Diagram
 GABA Synthesis, Release, Reuptake And Degradation Pathway antibodies  GABA Synthesis, Release, Reuptake And Degradation Pathway Diagram
 Glutamate Neurotransmitter Release Cycle Pathway antibodies  Glutamate Neurotransmitter Release Cycle Pathway Diagram
 Golgi Associated Vesicle Biogenesis Pathway antibodies  Golgi Associated Vesicle Biogenesis Pathway Diagram
 Insulin Signaling Pathway antibodies  Insulin Signaling Pathway Diagram
 Insulin Processing Pathway antibodies  Insulin Processing Pathway Diagram
Diseases associated with anti-VAMP2 antibodyOrgans/Tissues associated with anti-VAMP2 antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >43 publications with VAMP2 and Nervous System Diseases
 Disease Models, Animal Antibodies  >20 publications with VAMP2 and Disease Models, Animal
 Inflammation Antibodies  >11 publications with VAMP2 and Inflammation
 Seizures Antibodies  >7 publications with VAMP2 and Seizures
 Movement Disorders Antibodies  >6 publications with VAMP2 and Movement Disorders
 Cognition Disorders Antibodies  >6 publications with VAMP2 and Cognition Disorders
 Kidney Diseases Antibodies  >5 publications with VAMP2 and Kidney Diseases
 Learning Disorders Antibodies  >4 publications with VAMP2 and Learning Disorders
 Hypertension Antibodies  >4 publications with VAMP2 and Hypertension
 Memory Disorders Antibodies  >4 publications with VAMP2 and Memory Disorders
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >204 publications with VAMP2 and Brain
 Nerve Antibodies  >166 publications with VAMP2 and Nerve
 Muscle Antibodies  >71 publications with VAMP2 and Muscle
 Pancreas Antibodies  >37 publications with VAMP2 and Pancreas
 Blood Antibodies  >36 publications with VAMP2 and Blood
 Kidney Antibodies  >29 publications with VAMP2 and Kidney
 Eye Antibodies  >19 publications with VAMP2 and Eye
 Embryonic Tissue Antibodies  >14 publications with VAMP2 and Embryonic Tissue
 Salivary Gland Antibodies  >11 publications with VAMP2 and Salivary Gland
 Heart Antibodies  >10 publications with VAMP2 and Heart
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