View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List anti-VCAM1 antibody :: Rabbit VCAM1 Polyclonal Antibody Catalog # MBS2542657 Unit / Price 0.02 mL / $150 +1 FREE 8GB USB 0.06 mL / $205 +1 FREE 8GB USB 0.12 mL / $275 +1 FREE 8GB USB 0.2 mL / $410 +1 FREE 8GB USB 5x0.2 mL / $1,835 +2 FREE 8GB USB Previous Next Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name VCAM1, Polyclonal Antibody Popular Item Full Product Name VCAM1 Polyclonal Antibody Product Synonym Names CD106; INCAM-100 Product Gene Name anti-VCAM1 antibody[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP OMIM M30257 mRNA Clonality Polyclonal Isotype IgG Host Rabbit Species Reactivity Human, Mouse, Rat Purity/Purification Antigen Affinity Purification Concentration 1.7mg/ml (lot specific) Immunogen Fusion protein of human VCAM1 Buffer PBS with 0.05% sodium azide, 50% glycerol, pH7.3 Santa Cruz Alternative Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-1504 / sc-31048 / sc-8304 Preparation and Storage Store at -20 degree C. Avoid freeze/thaw cycles. ISO Certification Manufactured in an ISO 9001:2015 Certified Laboratory. Other Notes Small volumes of anti-VCAM1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-VCAM1 antibody This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. Product Categories/Family for anti-VCAM1 antibody Cancer Applications Tested/Suitable for anti-VCAM1 antibody ELISA (EIA), Immunohistochemistry (IHC) Application Notes for anti-VCAM1 antibody ELISA: 1:2000-5000IHC: 1:25-100 Immunohistochemistry (IHC) of anti-VCAM1 antibody Immunohistochemistry of paraffin-embedded Human liver cancer tissue using VCAM1 Polyclonal Antibody at dilution 1:30 Immunohistochemistry (IHC) of anti-VCAM1 antibody Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using VCAM1 Polyclonal Antibody at dilution 1:30 TOP NCBI/Uniprot data below describe general gene information for VCAM1. It may not necessarily be applicable to this product. NCBI GI # 340194 NCBI GeneID 7412 UniProt Secondary Accession # Q6NUP8; A8K6R7; B4DKS4; E9PDD1[Other Products] UniProt Related Accession # P19320[Other Products] Molecular Weight 74,346 Da TOP NCBI Official Full Name vascular cell adhesion molecule-1 NCBI Official Synonym Full Names vascular cell adhesion molecule 1 NCBI Official Symbol VCAM1 [Similar Products] NCBI Official Synonym Symbols CD106; INCAM-100 [Similar Products] NCBI Protein Information vascular cell adhesion protein 1 UniProt Protein Name Vascular cell adhesion protein 1 UniProt Synonym Protein Names INCAM-100; CD_antigen: CD106 Protein Family Vascular cell adhesion protein UniProt Gene Name VCAM1 [Similar Products] UniProt Synonym Gene Names L1CAM; V-CAM 1; VCAM-1 [Similar Products] UniProt Entry Name VCAM1_HUMAN TOP NCBI Summary for VCAM1 This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2010] TOP UniProt Comments for VCAM1 VCAM1: Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Cell adhesion; Membrane protein, integral; Motility/polarity/chemotaxisChromosomal Location of Human Ortholog: 1p32-p31Cellular Component: apical part of cell; cell surface; early endosome; endoplasmic reticulum; external side of plasma membrane; extracellular space; filopodium; Golgi apparatus; microvillus; plasma membrane; podosomeMolecular Function: amine oxidase activity; cell adhesion molecule binding; integrin bindingBiological Process: amine metabolic process; B cell differentiation; cell adhesion; cell-matrix adhesion; extracellular matrix organization and biogenesis; heterophilic cell adhesion; leukocyte adhesion; leukocyte tethering or rolling; membrane to membrane docking; positive regulation of T cell proliferation; regulation of immune response Research Articles on VCAM1 1. Denbinobin inhibited IL-1beta-induced ICAM-1/VCAM-1 expression and monocyte adhesion to osteoarthritis fibroblast-like synoviocytes via mirn146-a TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. 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TOP Products associated with anti-VCAM1 antibody Reference Product PubMed Publications ICAM1 antibody >140 publications with VCAM1 and ICAM1 CD44 antibody >18 publications with VCAM1 and CD44 ITGA4 antibody >11 publications with VCAM1 and ITGA4 ITGB2 antibody >5 publications with VCAM1 and ITGB2 ITGB1 antibody >4 publications with VCAM1 and ITGB1 IRF1 antibody >3 publications with VCAM1 and IRF1 SRC antibody >3 publications with VCAM1 and SRC ITGAD antibody >1 publications with VCAM1 and ITGAD Pathways associated with anti-VCAM1 antibody Products by Pathway Pathway Diagram AGE-RAGE Signaling Pathway In Diabetic Complications antibodies AGE-RAGE Signaling Pathway In Diabetic Complications Diagram AGE-RAGE Signaling Pathway In Diabetic Complications antibodies AGE-RAGE Signaling Pathway In Diabetic Complications Diagram Adaptive Immune System Pathway antibodies Adaptive Immune System Pathway Diagram African Trypanosomiasis Pathway antibodies African Trypanosomiasis Pathway Diagram African Trypanosomiasis Pathway antibodies African Trypanosomiasis Pathway Diagram Amplification And Expansion Of Oncogenic Pathways As Metastatic Traits antibodies Amplification And Expansion Of Oncogenic Pathways As Metastatic Traits Diagram Cell Adhesion Molecules (CAMs) Pathway antibodies Cell Adhesion Molecules (CAMs) Pathway Diagram Cell Adhesion Molecules (CAMs) Pathway antibodies Cell Adhesion Molecules (CAMs) Pathway Diagram Cellular Roles Of Anthrax Toxin Pathway antibodies Cellular Roles Of Anthrax Toxin Pathway Diagram Cytokine Signaling In Immune System Pathway antibodies Cytokine Signaling In Immune System Pathway Diagram Diseases associated with anti-VCAM1 antibody Disease Name Pubmed Publications Inflammation Antibodies >133 publications with VCAM1 and Inflammation Cardiovascular Diseases Antibodies >84 publications with VCAM1 and Cardiovascular Diseases Atherosclerosis Antibodies >65 publications with VCAM1 and Atherosclerosis Necrosis Antibodies >64 publications with VCAM1 and Necrosis Heart Diseases Antibodies >23 publications with VCAM1 and Heart Diseases Kidney Diseases Antibodies >20 publications with VCAM1 and Kidney Diseases Fibrosis Antibodies >17 publications with VCAM1 and Fibrosis Hypertension Antibodies >16 publications with VCAM1 and Hypertension Lung Diseases Antibodies >13 publications with VCAM1 and Lung Diseases Myocardial Ischemia Antibodies >11 publications with VCAM1 and Myocardial Ischemia Organs/Tissues associated with anti-VCAM1 antibody Organ/Tissue Name Pubmed Publications Vascular Antibodies >279 publications with VCAM1 and Vascular Blood Antibodies >163 publications with VCAM1 and Blood Heart Antibodies >33 publications with VCAM1 and Heart Brain Antibodies >31 publications with VCAM1 and Brain Kidney Antibodies >28 publications with VCAM1 and Kidney Embryonic Tissue Antibodies >26 publications with VCAM1 and Embryonic Tissue Lung Antibodies >23 publications with VCAM1 and Lung Liver Antibodies >22 publications with VCAM1 and Liver Skin Antibodies >10 publications with VCAM1 and Skin Adipose Tissue Antibodies >9 publications with VCAM1 and Adipose Tissue TOP