Q62059.2
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Versican core protein
NCBI Official Synonym Full Names
versican
NCBI Official Synonym Symbols
NG2; hdf; PG-M; Cspg2; DPEAAE; PG-M(V0); PG-M(V1); 9430051N09; 5430420N07Rik [Similar Products]
NCBI Protein Information
versican core protein; PG-M core protein; Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M); chondroitin sulfate proteoglycan 2; chondroitin sulfate proteoglycan core protein 2; heart defect; large fibroblast proteoglycan
UniProt Protein Name
Versican core protein
UniProt Synonym Protein Names
Chondroitin sulfate proteoglycan core protein 2; Chondroitin sulfate proteoglycan 2; Large fibroblast proteoglycan; PG-M
UniProt Synonym Gene Names
UniProt Entry Name
CSPG2_MOUSE
UniProt Comments for Vcan
CSPG2: May play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation. Binds hyaluronic acid. Defects in VCAN are the cause of Wagner syndrome type 1 (WGN1). WGN is a dominantly inherited vitreoretinopathy characterized by an optically empty vitreous cavity with fibrillary condensations and a preretinal avascular membrane. Other optical features include progressive chorioretinal atrophy, perivascular sheating, subcapsular cataract and myopia. Systemic manifestations are absent in WGN. Belongs to the aggrecan/versican proteoglycan family. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Secreted; Motility/polarity/chemotaxis; Cell adhesion
Cellular Component: extracellular matrix; proteinaceous extracellular matrix; extracellular space; cell surface; intracellular membrane-bound organelle; membrane; extracellular region
Molecular Function: extracellular matrix structural constituent; hyaluronic acid binding; calcium ion binding; carbohydrate binding; protein phosphatase binding
Biological Process: osteoblast differentiation; central nervous system development; heart development; regulation of phosphoprotein phosphatase activity; glial cell migration; cell adhesion; skeletal development
Research Articles on Vcan
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with anti-Vcan antibody
Organs/Tissues associated with anti-Vcan antibody
|