P01282.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
VIP peptides
NCBI Official Synonym Full Names
vasoactive intestinal peptide
NCBI Official Synonym Symbols
NCBI Protein Information
VIP peptides; prepro-VIP
UniProt Protein Name
VIP peptides
UniProt Synonym Protein Names
Peptide histidine valine 42
UniProt Synonym Gene Names
UniProt Entry Name
VIP_HUMAN
NCBI Summary for VIP
The protein encoded by this gene belongs to the glucagon family. It stimulates myocardial contractility, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea, stomach and gall bladder. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2014]
UniProt Comments for VIP
VIP: VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder. Belongs to the glucagon family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 6q25
Cellular Component: cell soma; extracellular region
Molecular Function: neuropeptide hormone activity; protein binding; hormone activity
Biological Process: negative regulation of smooth muscle cell proliferation; mRNA stabilization; negative regulation of potassium ion transport; regulation of signal transduction; positive regulation of vasodilation; body fluid secretion; G-protein coupled receptor protein signaling pathway; regulation of protein localization; learning and/or memory; positive regulation of cell proliferation; positive regulation of protein catabolic process; positive regulation of endothelial cell proliferation; regulation of sensory perception of pain; negative regulation of apoptosis
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Products associated with anti-VIP antibody
Pathways associated with anti-VIP antibody
Diseases associated with anti-VIP antibody
Organs/Tissues associated with anti-VIP antibody
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