NP_001180243.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
51kDa/57kDa
NCBI Official Full Name
spermatogenesis-defective protein 39 homolog isoform 1
NCBI Official Synonym Full Names
VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
NCBI Official Synonym Symbols
SPE39; VIPAR; SPE-39; VPS16B; hSPE-39; C14orf133 [Similar Products]
NCBI Protein Information
spermatogenesis-defective protein 39 homolog
UniProt Protein Name
Spermatogenesis-defective protein 39 homolog
UniProt Synonym Protein Names
VPS33B-interacting protein in apical-basolateral polarity regulator; VPS33B-interacting protein in polarity and apical restriction
UniProt Synonym Gene Names
NCBI Summary for VIPAS39
This gene encodes a protein involved in the sorting of lysosomal proteins. Mutations in this gene are associated with ARCS2 (arthrogryposis, renal dysfunction, and cholestasis-2). Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jul 2010]
UniProt Comments for VIPAS39
Proposed to be involved in endosomal maturation implicating in part VPS33B. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical RAB11A-dependent recycling pathway and in the maintenance of the apical-basolateral polarity (PubMed:20190753). May play a role in lysosomal trafficking, probably via association with the core HOPS complex in a discrete population of endosomes; the functions seems to be indepenedent of VPS33B (PubMed:19109425). May play a role in vesicular trafficking during spermatogenesis (). May be involved in direct or indirect transcriptional regulation of E-cadherin ().
Research Articles on VIPAS39
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Products associated with anti-VIPAS39 antibody
Diseases associated with anti-VIPAS39 antibody
Organs/Tissues associated with anti-VIPAS39 antibody
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