NP_001093901.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
33,857 Da
NCBI Official Full Name
V-set and immunoglobulin domain-containing protein 4 isoform 2
NCBI Official Synonym Full Names
V-set and immunoglobulin domain containing 4
NCBI Official Synonym Symbols
NCBI Protein Information
V-set and immunoglobulin domain-containing protein 4
UniProt Protein Name
V-set and immunoglobulin domain-containing protein 4
UniProt Synonym Protein Names
Protein Z39Ig
UniProt Synonym Gene Names
UniProt Entry Name
VSIG4_HUMAN
NCBI Summary for VSIG4
This gene encodes a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. The encoded protein may be a negative regulator of T-cell responses. This protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
UniProt Comments for VSIG4
VSIG4: Phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production. Potent inhibitor of the alternative complement pathway convertases. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Receptor, misc.
Chromosomal Location of Human Ortholog: Xq12-q13.3
Research Articles on VSIG4
Precautions
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Disclaimer
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Products associated with anti-VSIG4 antibody
Pathways associated with anti-VSIG4 antibody
Diseases associated with anti-VSIG4 antibody
Organs/Tissues associated with anti-VSIG4 antibody
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