Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow VASP rightarrow Polyclonal VASP  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • RAD54B Antibody
 • methionine sulfoxide reductase B2 (MSRB2) ELISA Kit
 • Carbohydrate Sulfotransferase 15 (CHST15) ELISA Kit
 • Akt (Ab-124) Antibody
 • TAF7L Peptide
 • HEMK1 Blocking Peptide
 • Interleukin 1 Beta (IL1b) ELISA Kit
 • Acyl Ghrelin (A GHR) ELISA Kit
 • TK1 Recombinant Protein
 • activated protein C, APC ELISA Kit
 • CD41 Antibody
 • Noggin Recombinant Protein
 • TTR - Transthyretin Antibody
 • KLK5 Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-VASP antibody :: Rabbit Vasodilator Stimulated Phosphoprotein Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS617738 anti-VASP antibody
Unit / Price
0.025 mg  /  $745 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Vasodilator Stimulated Phosphoprotein (VASP), Polyclonal Antibody

 Also Known As   

Vasodilator Stimulated Phosphoprotein (VASP)

 Product Synonym Names    Anti -Vasodilator Stimulated Phosphoprotein (VASP)
 Product Gene Name   

anti-VASP antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Chromosome Location    Chromosome: 19; NC_000019.9 (46010688..46030241). Location: 19q13.2-q13.3
 OMIM    601703
 3D Structure    ModBase 3D Structure for P50552
Section Bar
 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human, Mouse, Porcine
Section Bar
 Specificity    Recognizes human, mouse and pig VASP. Detects both the 46kDa (Ser157 dephospho) and 50kDa (Ser157 phospho) forms of VASP.
 Purity/Purification    Affinity Purified
Purified by affinity chromatography.
 Form/Format    Liquid. Purified antibody in PBS containing 1mg/ml BSA and 0.02% sodium azide.
Section Bar
Section Bar
 Preparation and Storage    -20 degree C
 Other Notes    Small volumes of anti-VASP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for anti-VASP antibody

   VASP (vasodilator stimulated phosphoprotein) plays an important role in ANF/NO/cGMP Protein kinase and cAMP/cAMP Protein kinase signalling pathways. VASP is expressed in almost all human and animal cell lines; particularly high concentrations are found in thrombocytes, vascular smooth muscle cells and fibroblasts. In cultured cells VASP is associated with focal contacts, cell-cell-contacts, microfilaments and dynamic membrane regions such as the leading edge. In vitro binding data show that VASP binds to profilin, zyxin, vinculin, and the Listeria spp. surface protein ActA. Functional evidence indicates that VASP is a crucial factor involved in the enhancement of actin filament formation. Ser 157 is a site preferred by cAMP-dependent protein kinase (PKA).
 Product Categories/Family for anti-VASP antibody    Antibodies; Abs to Proteins
 Applications Tested/Suitable for anti-VASP antibody   

Western Blot (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)

 Application Notes for anti-VASP antibody    Immunocytochemistry (formaldehyde fixed cells; 1ug/ml), Immunoprecipitation (2ug/ml), Western Blot (0.1ug/ml), Optimal conditions must be determined individually for each application.
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for VASP. It may not necessarily be applicable to this product.
 NCBI GI #    4507869
 NCBI GeneID    7408
 NCBI Accession #    NP_003361.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_003370.3 [Other Products]
Section Bar
 UniProt Primary Accession #    P50552 [Other Products]
 UniProt Secondary Accession #    Q6PIZ1; Q93035; B2RBT9 [Other Products]
 UniProt Related Accession #    P50552 [Other Products]
 Molecular Weight    39,830 Da [Similar Products]
Table BarTOPTable Bar
 NCBI Official Full Name    vasodilator-stimulated phosphoprotein
 NCBI Official Synonym Full Names    vasodilator-stimulated phosphoprotein
 NCBI Official Symbol    VASP [Similar Products]
 NCBI Official Synonym Symbols   
VASP
[Similar Products]
 NCBI Protein Information    vasodilator-stimulated phosphoprotein
 UniProt Protein Name    Vasodilator-stimulated phosphoprotein
 Protein Family    Vasodilator-stimulated phosphoprotein
 UniProt Gene Name    VASP [Similar Products]
 UniProt Entry Name    VASP_HUMAN
Section Bar
 NCBI Summary for VASP    Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq]
Section Bar
 UniProt Comments for VASP    VASP: vasodilator-stimulated phosphoprotein. Actin- and profilin-binding microfilament-associated protein. The phosphorylation of VASP is dynamically regulated by cellular adhesion to extracellular matrix.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 19q13.32

Cellular Component: filopodium membrane; tight junction; focal adhesion; cytoplasm; plasma membrane; cytosol; actin cytoskeleton

Molecular Function: protein binding; actin binding; SH3 domain binding; profilin binding

Biological Process: axon guidance; positive regulation of actin filament polymerization; actin polymerization and/or depolymerization; neural tube closure; T cell receptor signaling pathway; protein homotetramerization
Table BarTOPTable Bar
 Research Articles on VASP    1. Data show that VASP has different immunostaining patterns between cerebral cortical plates in prenatal and adult human brain samples, and suggest that VASP may play a crucial role in the regulation of human neonatal cerebral cortical development.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-VASP antibodyPathways associated with anti-VASP antibody
 Reference Product  PubMed Publications
 ZYX antibody  >28 publications with VASP and ZYX
 PFN1 antibody  >24 publications with VASP and PFN1
 FYB antibody  >7 publications with VASP and FYB
 LPP antibody  >6 publications with VASP and LPP
 PFN2 antibody  >5 publications with VASP and PFN2
 TES antibody  >5 publications with VASP and TES
 ABI1 antibody  >3 publications with VASP and ABI1
 Products by Pathway  Pathway Diagram
 Adaptive Immunity Signaling Pathway antibodies  Adaptive Immunity Signaling Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Cell Junction Organization Pathway antibodies  Cell Junction Organization Pathway Diagram
 Cell-extracellular Matrix Interactions Pathway antibodies  Cell-extracellular Matrix Interactions Pathway Diagram
 E-cadherin Signaling In Keratinocytes Pathway antibodies  E-cadherin Signaling In Keratinocytes Pathway Diagram
 Fc Gamma R-mediated Phagocytosis Pathway antibodies  Fc Gamma R-mediated Phagocytosis Pathway Diagram
 Fc Gamma R-mediated Phagocytosis Pathway antibodies  Fc Gamma R-mediated Phagocytosis Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
Diseases associated with anti-VASP antibodyOrgans/Tissues associated with anti-VASP antibody
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >94 publications with VASP and Cardiovascular Diseases
 Myocardial Ischemia Antibodies  >63 publications with VASP and Myocardial Ischemia
 Thrombosis Antibodies  >39 publications with VASP and Thrombosis
 Coronary Disease Antibodies  >39 publications with VASP and Coronary Disease
 Pain Antibodies  >31 publications with VASP and Pain
 Acute Coronary Syndrome Antibodies  >24 publications with VASP and Acute Coronary Syndrome
 Myocardial Infarction Antibodies  >19 publications with VASP and Myocardial Infarction
 Inflammation Antibodies  >17 publications with VASP and Inflammation
 Arteriosclerosis Antibodies  >16 publications with VASP and Arteriosclerosis
 Metabolic Diseases Antibodies  >15 publications with VASP and Metabolic Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >248 publications with VASP and Blood
 Vascular Antibodies  >119 publications with VASP and Vascular
 Muscle Antibodies  >64 publications with VASP and Muscle
 Brain Antibodies  >53 publications with VASP and Brain
 Embryonic Tissue Antibodies  >31 publications with VASP and Embryonic Tissue
 Kidney Antibodies  >24 publications with VASP and Kidney
 Lung Antibodies  >20 publications with VASP and Lung
 Liver Antibodies  >11 publications with VASP and Liver
 Bone Antibodies  >10 publications with VASP and Bone
 Spleen Antibodies  >7 publications with VASP and Spleen
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions