NP_058543.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
NCBI Official Full Name
vasopressin V1a receptor
NCBI Official Synonym Full Names
arginine vasopressin receptor 1A
NCBI Protein Information
vasopressin V1a receptor; AVPR V1a; OTTMUSP00000022915; antidiuretic hormone receptor 1a; V1a arginine vasopressin receptor; vascular/hepatic-type arginine vasopressin receptor
UniProt Protein Name
Arginine vasopressin receptor 1A
UniProt Entry Name
Q3U1H9_MOUSE
NCBI Summary for Avpr1a
This gene encodes a receptor for arginine vasopressin, a neurohypophyseal hormone involved in diuresis inhibition, smooth muscle contraction, liver glycogenolysis stimulation and regulation of adrenocorticotropic hormone release from the pituitary. This receptor represents one of three G protein-coupled arginine vasopressin receptors which functions through a phosphotidylinositol-calcium second messenger system in vascular and hepatic tissues [provided by RefSeq]
UniProt Comments for Avpr1a
AVPR1A: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1; Receptor, GPCR
Cellular Component: membrane; integral to plasma membrane; integral to membrane; plasma membrane; cytoplasmic vesicle; cytosol
Molecular Function: G-protein coupled receptor activity; signal transducer activity; peptide hormone binding; V1A vasopressin receptor binding; peptide binding; vasopressin receptor activity
Biological Process: grooming behavior; response to inorganic substance; maternal behavior; positive regulation of cellular pH reduction; calcium-mediated signaling; positive regulation of glutamate secretion; positive regulation of heart rate; positive regulation of systemic arterial blood pressure; social behavior; signal transduction; positive regulation of cell growth; cellular response to hormone stimulus; response to organic substance; negative regulation of female receptivity; G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; negative regulation of transmission of nerve impulse; regulation of systemic arterial blood pressure by vasopressin; positive regulation of cell proliferation; positive regulation of vasoconstriction; sperm ejaculation; positive regulation of blood pressure; positive regulation of prostaglandin biosynthetic process; penile erection
Research Articles on Avpr1a
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Pathways associated with anti-Avpr1a antibody
Diseases associated with anti-Avpr1a antibody
Organs/Tissues associated with anti-Avpr1a antibody
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