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anti-VAMP7 antibody :: Rabbit anti-Human Vesicle-associated membrane protein 7 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7001233
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Vesicle-associated membrane protein 7 (VAMP7), Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-human Vesicle-associated membrane protein 7 polyclonal Antibody

 Product Synonym Names    Synaptobrevin-like protein 1; Tetanus-insensitive VAMP
 Product Gene Name   

anti-VAMP7 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    300053
 3D Structure    ModBase 3D Structure for P51809
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Caprylic Acid Ammonium Sulfate Precipitation purified
 Form/Format    Liquid
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 Immunogen    Recombinant human Vesicle-associated membrane protein 7 protein
 Conjugation    Non-conjugated
 Storage Buffer    Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-32592 / sc-32593 / sc-67060
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-VAMP7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-VAMP7 antibody

   Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis. Involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. Required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. Required for focal exocytosis of late endocytic vesicles during phagosome formation.
 Product Categories/Family for anti-VAMP7 antibody    Cell Cycle
 Applications Tested/Suitable for anti-VAMP7 antibody   

ELISA (EIA), Immunohistochemistry (IHC)

 Application Notes for anti-VAMP7 antibody    Recommended dilution: IHC: 1:20-1:200
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 Immunohistochemistry (IHC) of anti-VAMP7 antibody    Immunohistochemistry of paraffin-embeded human colorectal carcinoma using MBS7001233 at dilution of 1:100
anti-VAMP7 antibody Immunohistochemistry (IHC) (IHC) image
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 Western Blot (WB) of anti-VAMP7 antibody    Western Blot
Positive WB detected in: Mouse brain tissue,Mouse liver tissue,Mouse kidney tissue
All lanes: VAMP7 antibody at 2ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 25 KDa
Observed band size: 25 KDa

anti-VAMP7 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-VAMP7 antibody    Immunohistochemistry of paraffin-embedded human lung tissue using MBS7001233 at dilution of 1:100
anti-VAMP7 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-VAMP7 antibody    Immunohistochemistry of paraffin-embedded human small intestine tissue using MBS7001233 at dilution of 1:100
anti-VAMP7 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunofluorescence (IF) of anti-VAMP7 antibody    Immunofluorescent analysis of HepG2 cells using MBS7001233 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-VAMP7 antibody Immunofluorescence (IF) image
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NCBI/Uniprot data below describe general gene information for VAMP7. It may not necessarily be applicable to this product.
 NCBI GI #    223468574
 NCBI GeneID    6845
 NCBI Accession #    NP_001138621.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001145149.2 [Other Products]
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 UniProt Primary Accession #    P51809 [Other Products]
 UniProt Secondary Accession #    Q53GY7; Q7Z409; Q9H4A7 [Other Products]
 UniProt Related Accession #    P51809 [Other Products]
 Molecular Weight    20,121 Da
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 NCBI Official Full Name    vesicle-associated membrane protein 7 isoform 2
 NCBI Official Synonym Full Names    vesicle associated membrane protein 7
 NCBI Official Symbol    VAMP7 [Similar Products]
 NCBI Official Synonym Symbols   
SYBL1; TIVAMP; VAMP-7; TI-VAMP
[Similar Products]
 NCBI Protein Information    vesicle-associated membrane protein 7
 UniProt Protein Name    Vesicle-associated membrane protein 7
 UniProt Synonym Protein Names   
Synaptobrevin-like protein 1; Tetanus-insensitive VAMP; Ti-VAMP
 Protein Family    Vesicle-associated membrane protein
 UniProt Gene Name    VAMP7 [Similar Products]
 UniProt Synonym Gene Names    SYBL1; VAMP-7; Ti-VAMP [Similar Products]
 UniProt Entry Name    VAMP7_HUMAN
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 NCBI Summary for VAMP7    This gene encodes a transmembrane protein that is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) family. The encoded protein localizes to late endosomes and lysosomes and is involved in the fusion of transport vesicles to their target membranes. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010]
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 UniProt Comments for VAMP7    VAMP7: Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis. Involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. Required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. Required for focal exocytosis of late endocytic vesicles during phagosome formation. Belongs to the synaptobrevin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: Xq28 and Yq12

Cellular Component: apical part of cell; cell junction; cell surface; cytoplasm; endoplasmic reticulum membrane; integral to membrane; intracellular membrane-bound organelle; lamellipodium; late endosome membrane; lysosomal membrane; membrane; neuron projection; perinuclear region of cytoplasm; phagocytic vesicle; phagocytic vesicle membrane; plasma membrane; pseudopodium; secretory granule; secretory granule membrane; SNARE complex; synapse; trans-Golgi network

Molecular Function: protein binding; SNAP receptor activity; SNARE binding; syntaxin binding

Biological Process: calcium ion-dependent exocytosis; endosome to lysosome transport; eosinophil degranulation; ER to Golgi vesicle-mediated transport; Golgi to plasma membrane protein transport; natural killer cell degranulation; neutrophil degranulation; phagocytosis, engulfment; positive regulation of dendrite morphogenesis; post-Golgi vesicle-mediated transport; triacylglycerol transport; vesicle fusion; vesicle fusion with Golgi apparatus; vesicle transport along microtubule; vesicle-mediated transport
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 Research Articles on VAMP7    1. GLUT5 required an interaction cascade of Rab11, Myo5B, Slp4a, Munc18-2, and Vamp7 with Stx3.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-VAMP7 antibodyPathways associated with anti-VAMP7 antibody
 Reference Product  PubMed Publications
 SNAP23 antibody  >13 publications with VAMP7 and SNAP23
 VTI1A antibody  >10 publications with VAMP7 and VTI1A
 VTI1B antibody  >5 publications with VAMP7 and VTI1B
 YKT6 antibody  >4 publications with VAMP7 and YKT6
 STX12 antibody  >2 publications with VAMP7 and STX12
 STX17 antibody  >1 publications with VAMP7 and STX17
 STX7 antibody  >1 publications with VAMP7 and STX7
 Products by Pathway  Pathway Diagram
 Clathrin Derived Vesicle Budding Pathway antibodies  Clathrin Derived Vesicle Budding Pathway Diagram
 Golgi Associated Vesicle Biogenesis Pathway antibodies  Golgi Associated Vesicle Biogenesis Pathway Diagram
 Lysosome Vesicle Biogenesis Pathway antibodies  Lysosome Vesicle Biogenesis Pathway Diagram
 Membrane Trafficking Pathway antibodies  Membrane Trafficking Pathway Diagram
 SNARE Interactions In Vesicular Transport Pathway antibodies  SNARE Interactions In Vesicular Transport Pathway Diagram
 SNARE Interactions In Vesicular Transport Pathway antibodies  SNARE Interactions In Vesicular Transport Pathway Diagram
 Vesicle-mediated Transport Pathway antibodies  Vesicle-mediated Transport Pathway Diagram
 Trans-Golgi Network Vesicle Budding Pathway antibodies  Trans-Golgi Network Vesicle Budding Pathway Diagram
Diseases associated with anti-VAMP7 antibodyOrgans/Tissues associated with anti-VAMP7 antibody
 Disease Name  Pubmed Publications
 Congenital, Hereditary, and Neonatal Diseases and Abnormalities Antibodies  >8 publications with VAMP7 and Congenital, Hereditary, and Neonatal Diseases and Abnormalities
 Death Antibodies  >6 publications with VAMP7 and Death
 Chromosome Aberrations Antibodies  >2 publications with VAMP7 and Chromosome Aberrations
 Cardiovascular Diseases Antibodies  >2 publications with VAMP7 and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >2 publications with VAMP7 and Disease Models, Animal
 Gonadal Disorders Antibodies  >2 publications with VAMP7 and Gonadal Disorders
 Neurobehavioral Manifestations Antibodies  >1 publications with VAMP7 and Neurobehavioral Manifestations
 Neoplasms, Experimental Antibodies  >1 publications with VAMP7 and Neoplasms, Experimental
 Fibrosis Antibodies  >1 publications with VAMP7 and Fibrosis
 Breast Neoplasms Antibodies  >1 publications with VAMP7 and Breast Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >14 publications with VAMP7 and Blood
 Brain Antibodies  >14 publications with VAMP7 and Brain
 Kidney Antibodies  >8 publications with VAMP7 and Kidney
 Intestine Antibodies  >6 publications with VAMP7 and Intestine
 Liver Antibodies  >3 publications with VAMP7 and Liver
 Muscle Antibodies  >3 publications with VAMP7 and Muscle
 Stomach Antibodies  >2 publications with VAMP7 and Stomach
 Bone Antibodies  >2 publications with VAMP7 and Bone
 Eye Antibodies  >2 publications with VAMP7 and Eye
 Ovary Antibodies  >1 publications with VAMP7 and Ovary
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