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anti-SLC18A3 antibody :: Rabbit Vesicular Acetylcholine Transporter Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS832831 anti-SLC18A3 antibody
Unit / Price
0.05 mL  /  $865 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Vesicular Acetylcholine Transporter (SLC18A3), Polyclonal Antibody

 Also Known As   

Vesicular Acetylcholine Transporter antibody

 Product Synonym Names    Polyclonal Vesicular Acetylcholine Transporter; Anti Vesicular Acetylcholine Transporter; VAChT
 Product Gene Name   

anti-SLC18A3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    600336
 3D Structure    ModBase 3D Structure for Q16572
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    To be determined by the end user
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 Form/Format    Supplied in lyophilized form. Dissolve the antiserum in 50 - 100 ul distilled water and dilute further in 0.1 M PBS with 1% BSA and 0.1% Na-azide
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 Biological Significance    The Vesicular acetylcholine transporter (VAChT) is a neurotransmitter transporter which is responsible for loading acetylcholine (ACh) into secretory organelles in neurons making acetylcholine available for secretion.
 Immunogen    Vesicular Acetylcholine Transporter antibody was raised in rabbit using synthetic peptide from the C-terminus of human VAChT conjugated to BSA as the immunogen.
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 Preparation and Storage    Store at 2-8 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
 Other Notes    Small volumes of anti-SLC18A3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-SLC18A3 antibody

   Rabbit polyclonal Vesicular Acetylcholine Transporter antibody
 Product Categories/Family for anti-SLC18A3 antibody    Hormones & Steroids
 Applications Tested/Suitable for anti-SLC18A3 antibody   

Immunohistochemistry (IHC)

 Application Notes for anti-SLC18A3 antibody    IHC: 1:800 - 1:1200
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NCBI/Uniprot data below describe general gene information for SLC18A3. It may not necessarily be applicable to this product.
 NCBI GI #    118582257
 NCBI GeneID    6572
 NCBI Accession #    NP_003046.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_003055.2 [Other Products]
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 UniProt Primary Accession #    Q16572 [Other Products]
 UniProt Secondary Accession #    B2R7S1 [Other Products]
 UniProt Related Accession #    Q16572 [Other Products]
 Molecular Weight    56,903 Da [Similar Products]
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 NCBI Official Full Name    vesicular acetylcholine transporter
 NCBI Official Synonym Full Names    solute carrier family 18 (vesicular acetylcholine transporter), member 3
 NCBI Official Symbol    SLC18A3 [Similar Products]
 NCBI Official Synonym Symbols   
VACHT
[Similar Products]
 NCBI Protein Information    vesicular acetylcholine transporter
 UniProt Protein Name    Vesicular acetylcholine transporter
 UniProt Synonym Protein Names   
Solute carrier family 18 member 3
 Protein Family    Vesicular acetylcholine transporter
 UniProt Gene Name    SLC18A3 [Similar Products]
 UniProt Synonym Gene Names    VACHT; VAChT [Similar Products]
 UniProt Entry Name    VACHT_HUMAN
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 NCBI Summary for SLC18A3    This gene is a member of the vesicular amine transporter family. The encoded transmembrane protein transports acetylcholine into secretory vesicles for release into the extracellular space. Acetylcholine transport utilizes a proton gradient established by a vacuolar ATPase. This gene is located within the first intron of the choline acetyltransferase gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for SLC18A3    SLC18A3: Involved in acetylcholine transport into synaptic vesicles. Belongs to the major facilitator superfamily. Vesicular transporter family.

Protein type: Transporter, SLC family; Transporter; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 10q11.2

Cellular Component: membrane; integral to plasma membrane; plasma membrane

Molecular Function: acetylcholine transmembrane transporter activity

Biological Process: synaptic transmission; acetylcholine transport; neurotransmitter secretion
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 Research Articles on SLC18A3    1. PCMC expression of ADAM29, FLRT2, and SLC18A3 could be assessed as part of a routine screen to help identify individuals at risk of severe Obstructive sleep apnea in Asian populations
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-SLC18A3 antibodyPathways associated with anti-SLC18A3 antibody
 Reference Product  PubMed Publications
 CHAT antibody  >130 publications with SLC18A3 and CHAT
 RAB3A antibody  >2 publications with SLC18A3 and RAB3A
 SNAP25 antibody  >2 publications with SLC18A3 and SNAP25
 Products by Pathway  Pathway Diagram
 Acetylcholine Neurotransmitter Release Cycle Pathway antibodies  Acetylcholine Neurotransmitter Release Cycle Pathway Diagram
 Cholinergic Synapse Pathway antibodies  Cholinergic Synapse Pathway Diagram
 Neuronal System Pathway antibodies  Neuronal System Pathway Diagram
 Neurotransmitter Release Cycle Pathway antibodies  Neurotransmitter Release Cycle Pathway Diagram
 Synaptic Vesicle Pathway antibodies  Synaptic Vesicle Pathway Diagram
 Synaptic Vesicle Cycle Pathway antibodies  Synaptic Vesicle Cycle Pathway Diagram
 Synaptic Vesicle Cycle Pathway antibodies  Synaptic Vesicle Cycle Pathway Diagram
 Transmission Across Chemical Synapses Pathway antibodies  Transmission Across Chemical Synapses Pathway Diagram
Diseases associated with anti-SLC18A3 antibodyOrgans/Tissues associated with anti-SLC18A3 antibody
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >11 publications with SLC18A3 and Cardiovascular Diseases
 Memory Disorders Antibodies  >10 publications with SLC18A3 and Memory Disorders
 Learning Disorders Antibodies  >9 publications with SLC18A3 and Learning Disorders
 Cognition Disorders Antibodies  >9 publications with SLC18A3 and Cognition Disorders
 Vascular Diseases Antibodies  >9 publications with SLC18A3 and Vascular Diseases
 Inflammation Antibodies  >9 publications with SLC18A3 and Inflammation
 Neurobehavioral Manifestations Antibodies  >8 publications with SLC18A3 and Neurobehavioral Manifestations
 Movement Disorders Antibodies  >7 publications with SLC18A3 and Movement Disorders
 Hypertension Antibodies  >5 publications with SLC18A3 and Hypertension
 Congenital Abnormalities Antibodies  >5 publications with SLC18A3 and Congenital Abnormalities
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >186 publications with SLC18A3 and Brain
 Eye Antibodies  >21 publications with SLC18A3 and Eye
 Liver Antibodies  >12 publications with SLC18A3 and Liver
 Placenta Antibodies  >3 publications with SLC18A3 and Placenta
 Testis Antibodies  >1 publications with SLC18A3 and Testis
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