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anti-WDFY3 antibody :: Rabbit WD repeat and FYVE domain containing 3 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS712132 anti-WDFY3 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

WD repeat and FYVE domain containing 3 (WDFY3), Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-human WD repeat and FYVE domain containing 3 polyclonal Antibody

 Product Synonym Names    WD repeat and FYVE domain containing 3; WDFY3; ALFY; KIAA0993; MGC16461; ZFYVE25
 Product Gene Name   

anti-WDFY3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human WDFY3
 Storage Buffer    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-162395
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-WDFY3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-WDFY3 antibody   

ELISA (EIA), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for WDFY3. It may not necessarily be applicable to this product.
 NCBI GI #    156230428
 NCBI GeneID    23001
 NCBI Accession #    AAI48299.1 [Other Products]
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 UniProt Secondary Accession #    Q4W5K5; Q6P0Q5; Q8N1T2; Q8NAV6; Q96BS7; Q96D33; Q96N85; Q9Y2J7 [Other Products]
 UniProt Related Accession #    Q8IZQ1 [Other Products]
 Molecular Weight    393,367 Da [Similar Products]
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 NCBI Official Full Name    WD repeat and FYVE domain containing 3
 NCBI Official Synonym Full Names    WD repeat and FYVE domain containing 3
 NCBI Official Symbol    WDFY3 [Similar Products]
 NCBI Official Synonym Symbols   
ALFY; ZFYVE25
[Similar Products]
 NCBI Protein Information    WD repeat and FYVE domain-containing protein 3; autophagy-linked FYVE protein
 UniProt Protein Name    WD repeat and FYVE domain-containing protein 3
 UniProt Synonym Protein Names   
Autophagy-linked FYVE protein; Alfy
 Protein Family    WD repeat and FYVE domain-containing protein
 UniProt Gene Name    WDFY3 [Similar Products]
 UniProt Synonym Gene Names    KIAA0993; Alfy [Similar Products]
 UniProt Entry Name    WDFY3_HUMAN
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 NCBI Summary for WDFY3    This gene encodes a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy. This protein shuttles from the nuclear membrane to colocalize with aggregated proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy. [provided by RefSeq, May 2010]
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 UniProt Comments for WDFY3    WDFY3: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Lipid-binding; Nuclear envelope; Membrane protein, peripheral; Transferase

Chromosomal Location of Human Ortholog: 4q21.23

Cellular Component: PML body; nuclear membrane; extrinsic to membrane; cytoplasm; autophagic vacuole; nuclear envelope; inclusion body

Molecular Function: beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity; protein binding; metal ion binding; phosphatidylinositol binding

Biological Process: endosome transport; positive regulation of macroautophagy
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 Research Articles on WDFY3    1. increasing Alfy-mediated protein degradation may be beneficial in some organs, but may be detrimental in others
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-WDFY3 antibodyOrgans/Tissues associated with anti-WDFY3 antibody
 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >1 publications with WDFY3 and Liver Diseases
 Brain Diseases Antibodies  >1 publications with WDFY3 and Brain Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2 publications with WDFY3 and Brain
 Bone Antibodies  >1 publications with WDFY3 and Bone
 Liver Antibodies  >1 publications with WDFY3 and Liver
 Muscle Antibodies  >1 publications with WDFY3 and Muscle
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