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anti-BRWD1 antibody :: Chicken anti-Human WDR9 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS613929 anti-BRWD1 antibody
Unit / Price
0.5 mg  /  $570 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

WDR9 (BRWD1), Polyclonal Antibody

 Also Known As   

WDR9 (WDR9, WD repeat domain 9, 90/3H1, FLJ11315, cAMP response element binding and beta-tranducin family-like)

 Product Synonym Names    Anti -WDR9 (WDR9, WD repeat domain 9, 90/3H1, FLJ11315, cAMP response element binding and beta-tranducin family-like)
 Product Gene Name   

anti-BRWD1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    chromosome: 21; Location: 21q22.2
 3D Structure    ModBase 3D Structure for Q9NSI6
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 Clonality    Polyclonal
 Isotype    IgY
 Host    Chicken
 Species Reactivity    Human
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 Specificity    Recognizes WDR9.3.
 Purity/Purification    Purified
Purified
 Form/Format    Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide.
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 Immunogen    Purified WDR9.3 recombinant protein
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 Preparation and Storage    May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20 degree C or colder. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of anti-BRWD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-BRWD1 antibody

   WDR9.3, a novel protein (57KD) from human chromosome 21.
 Product Categories/Family for anti-BRWD1 antibody    Antibodies; Abs to WD Repeat Proteins
 Applications Tested/Suitable for anti-BRWD1 antibody   

Western Blot (WB)

 Application Notes for anti-BRWD1 antibody    Can be used at 1:500-1:5000 for immunoblot testing.
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NCBI/Uniprot data below describe general gene information for BRWD1. It may not necessarily be applicable to this product.
 NCBI GI #    14970564
 NCBI GeneID    54014
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 UniProt Primary Accession #    Q9NSI6 [Other Products]
 UniProt Secondary Accession #    O43721; Q5R2V0; Q5R2V1; Q8TCV3; Q96QG9; Q96QH0; Q9NUK1; C9JK25 [Other Products]
 UniProt Related Accession #    Q5R2U4; Q5R2U5; Q5R2U6; Q5R2U7; Q5R2U8; Q5R2U9; Q6P2D1; Q9NSI6 [Other Products]
 Molecular Weight    262,936 Da [Similar Products]
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 NCBI Official Full Name    WDR9 protein, form B
 NCBI Official Synonym Full Names    bromodomain and WD repeat domain containing 1
 NCBI Official Symbol    BRWD1 [Similar Products]
 NCBI Official Synonym Symbols   
N143; WDR9; FLJ43918; C21orf107; BRWD1
[Similar Products]
 NCBI Protein Information    bromodomain and WD repeat-containing protein 1; WD repeat domain 9; transcriptional unit N143; WD repeat protein WDR9-form2; WD repeat-containing protein 9; cAMP response element binding and beta-tranducin family-like
 UniProt Protein Name    Bromodomain and WD repeat-containing protein 1
 UniProt Synonym Protein Names   
WD repeat-containing protein 9
 Protein Family    Bromodomain and WD repeat-containing protein
 UniProt Gene Name    BRWD1 [Similar Products]
 UniProt Synonym Gene Names    C21orf107; WDR9 [Similar Products]
 UniProt Entry Name    BRWD1_HUMAN
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 NCBI Summary for BRWD1    This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats, and the function of this protein is not known. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates 3 transcript variants diverging at the 3' ends. [provided by RefSeq]
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 UniProt Comments for BRWD1    WDR9: an ubiquitously expressed WD40 repeat protein that may be a transcriptional activator and be involved in chromatin remodeling. Interacts with SMARCA4. WD40 repeats are found in a number of eukaryotic proteins that coordinate multi-protein complex assemblies. WD40 proteins are implicated in many functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. Three alternatively spliced human isoforms have been described.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 21q22.2

Cellular Component: cytoplasm; nucleolus; nucleus

Biological Process: regulation of transcription from RNA polymerase II promoter; regulation of cell shape; transcription, DNA-dependent; cytoskeleton organization and biogenesis
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 Research Articles on BRWD1    1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
2. Observational study and genome-wide association study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
3. isolation and characterization of the gene located in the Down Syndrome critical region-2 of chromosome 21
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-BRWD1 antibody
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >1 publications with BRWD1 and Necrosis
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