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anti-WIZ antibody :: Goat WIZ Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS421804
Western Blot (WB)
Unit / Price
0.1 mg  /  $300 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

WIZ, Polyclonal Antibody

 Also Known As   

Goat anti-WIZ Antibody

 Product Synonym Names    WIZ; widely interspaced zinc finger motifs; ZNF803; WIZ zinc finger; widely-interspaced zinc finger motifs; WIZ antibody; widely interspaced zinc finger motifs antibody; ZNF803 antibody; WIZ zinc finger antibody; widely-interspaced zinc finger motifs antibody
 Product Gene Name   

anti-WIZ antibody

[Similar Products]
 Antibody/Peptide Pairs    WIZ peptide (MBS425525) is used for blocking the activity of WIZ antibody (MBS421804)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    RSYIQGGRPF TKKFR
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 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Tested: Human; Expected from sequence similarity: Human, Mouse, Rat
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 Purity/Purification    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
 Form/Format    Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
 Concentration    100ug specific antibody in 200ul (lot specific)
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 Immunogen    Peptide with sequence C-RSYIQGGRPFTKKFR, from the internal region of the protein sequence according to NP_067064.2.
 Epitope    Internal region
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 Preparation and Storage    Aliquot and store at -20 degree C. Minimize freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-WIZ antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-WIZ antibody   

Peptide ELISA (EIA), Western Blot (WB)

 Application Notes for anti-WIZ antibody    Peptide ELISA: Antibody detection limit dilution 1: 2000.
Western Blot: Approx 75kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 85.4kDa according to NP_067064.2). Recommended concentration: 0.3-1ug/ml.
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 Western Blot (WB) of anti-WIZ antibody    (0.3ug/ml) staining of Human Cerebellum lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
anti-WIZ antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for WIZ. It may not necessarily be applicable to this product.
 NCBI GI #    151301215
 NCBI GeneID    58525
 NCBI Accession #    NP_067064.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_021241.2 [Other Products]
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 UniProt Secondary Accession #    Q4G0E0; Q6P6B0; Q6ZN24; Q7LDY6; Q7LDZ1; Q96IG5; Q96SQ6; Q9BUR8; B3KVH1; B7ZM82; M0QY21 [Other Products]
 UniProt Related Accession #    O95785 [Other Products]
 Molecular Weight    89,356 Da
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 NCBI Official Full Name    protein Wiz
 NCBI Official Synonym Full Names    widely interspaced zinc finger motifs
 NCBI Official Symbol    WIZ [Similar Products]
 NCBI Official Synonym Symbols   
ZNF803
[Similar Products]
 NCBI Protein Information    protein Wiz
 UniProt Protein Name    Protein Wiz
 UniProt Synonym Protein Names   
Widely-interspaced zinc finger-containing protein; Zinc finger protein 803
 Protein Family    Protein
 UniProt Gene Name    WIZ [Similar Products]
 UniProt Synonym Gene Names    ZNF803 [Similar Products]
 UniProt Entry Name    WIZ_HUMAN
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 UniProt Comments for WIZ    WIZ: May link EHMT1 and EHMT2 histone methyltransferases to the CTBP corepressor machinery. May be involved in EHMT1-EHMT2 heterodimer formation and stabilization. Belongs to the krueppel C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 19p13.1

Cellular Component: nucleus

Molecular Function: metal ion binding; protein binding

Biological Process: protein stabilization
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 Research Articles on WIZ    1. Disrupting the association of G9a-GLP with chromatin by depleting WIZ resulted in altered gene expression and protein-protein interactions that were distinguishable from that of small molecule-based inhibition of G9a/GLP
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-WIZ antibodyOrgans/Tissues associated with anti-WIZ antibody
 Disease Name  Pubmed Publications
 Chromosome Aberrations Antibodies  >1 publications with WIZ and Chromosome Aberrations
 Prostatic Diseases Antibodies  >1 publications with WIZ and Prostatic Diseases
 Death Antibodies  >1 publications with WIZ and Death
 Memory Disorders Antibodies  >1 publications with WIZ and Memory Disorders
 Carcinoma Antibodies  >1 publications with WIZ and Carcinoma
 Fetal Growth Retardation Antibodies  >1 publications with WIZ and Fetal Growth Retardation
 Inflammation Antibodies  >1 publications with WIZ and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2 publications with WIZ and Blood
 Embryonic Tissue Antibodies  >2 publications with WIZ and Embryonic Tissue
 Muscle Antibodies  >2 publications with WIZ and Muscle
 Brain Antibodies  >2 publications with WIZ and Brain
 Prostate Antibodies  >1 publications with WIZ and Prostate
 Bone Antibodies  >1 publications with WIZ and Bone
 Placenta Antibodies  >1 publications with WIZ and Placenta
 Vascular Antibodies  >1 publications with WIZ and Vascular
 Heart Antibodies  >1 publications with WIZ and Heart
 Uncharacterized Tissue Antibodies  >1 publications with WIZ and Uncharacterized Tissue
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