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| Product Name
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WIZ, Polyclonal Antibody
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| Also Known As
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Goat anti-WIZ Antibody
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| Product Synonym Names
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WIZ; widely interspaced zinc finger motifs; ZNF803; WIZ zinc finger; widely-interspaced zinc finger motifs; WIZ antibody; widely interspaced zinc finger motifs antibody; ZNF803 antibody; WIZ zinc finger antibody; widely-interspaced zinc finger motifs antibody
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| Product Gene Name
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[Similar Products]
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| Antibody/Peptide Pairs
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WIZ peptide (MBS425525) is used for blocking the activity of WIZ antibody (MBS421804)
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| Research Use Only
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For Research Use Only. Not for use in diagnostic procedures.
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 TOP
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| Immunogen Sequence
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RSYIQGGRPF TKKFR
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| Clonality
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Polyclonal
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| Host
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Goat
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| Species Reactivity
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Tested: Human; Expected from sequence similarity: Human, Mouse, Rat
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| Purity/Purification
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Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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| Form/Format
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Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
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| Concentration
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100ug specific antibody in 200ul (lot specific)
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| Immunogen
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Peptide with sequence C-RSYIQGGRPFTKKFR, from the internal region of the protein sequence according to NP_067064.2.
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| Epitope
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Internal region
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| Preparation and Storage
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Aliquot and store at -20 degree C. Minimize freezing and thawing.
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| ISO Certification
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Manufactured in an ISO 9001:2015 Certified Laboratory.
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| Other Notes
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Small volumes of anti-WIZ antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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TOP
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| Applications Tested/Suitable for anti-WIZ antibody
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Peptide ELISA (EIA), Western Blot (WB)
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| Application Notes for anti-WIZ antibody
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Peptide ELISA: Antibody detection limit dilution 1: 2000.
Western Blot: Approx 75kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 85.4kDa according to NP_067064.2). Recommended concentration: 0.3-1ug/ml.
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| Western Blot (WB) of anti-WIZ antibody
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(0.3ug/ml) staining of Human Cerebellum lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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TOP
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| NCBI/Uniprot data below describe general gene information for WIZ. It may not necessarily be applicable to this product. |
| NCBI GI #
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151301215
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| NCBI GeneID
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58525
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| NCBI Accession #
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NP_067064.2
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[Other Products]
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| NCBI GenBank Nucleotide #
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NM_021241.2
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[Other Products]
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| UniProt Secondary Accession #
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Q4G0E0; Q6P6B0; Q6ZN24; Q7LDY6; Q7LDZ1; Q96IG5; Q96SQ6; Q9BUR8; B3KVH1; B7ZM82; M0QY21
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[Other Products]
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| UniProt Related Accession #
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O95785
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[Other Products]
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| Molecular Weight
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89,356 Da
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TOP
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| NCBI Official Full Name
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protein Wiz
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| NCBI Official Synonym Full Names
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widely interspaced zinc finger motifs
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| NCBI Official Symbol
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WIZ
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[Similar Products]
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| NCBI Official Synonym Symbols
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ZNF803
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[Similar Products]
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| NCBI Protein Information
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protein Wiz
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| UniProt Protein Name
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Protein Wiz
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| UniProt Synonym Protein Names
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Widely-interspaced zinc finger-containing protein; Zinc finger protein 803
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| Protein Family
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Protein
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| UniProt Gene Name
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WIZ
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[Similar Products]
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| UniProt Synonym Gene Names
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ZNF803
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[Similar Products]
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| UniProt Entry Name
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WIZ_HUMAN
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| UniProt Comments for WIZ
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WIZ: May link EHMT1 and EHMT2 histone methyltransferases to the CTBP corepressor machinery. May be involved in EHMT1-EHMT2 heterodimer formation and stabilization. Belongs to the krueppel C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: C2H2-type zinc finger protein
Chromosomal Location of Human Ortholog: 19p13.1
Cellular Component: nucleus
Molecular Function: metal ion binding; protein binding
Biological Process: protein stabilization
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TOP
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| Research Articles on WIZ
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1. Disrupting the association of G9a-GLP with chromatin by depleting WIZ resulted in altered gene expression and protein-protein interactions that were distinguishable from that of small molecule-based inhibition of G9a/GLP
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| Precautions
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All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
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| Disclaimer
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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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| Diseases associated with anti-WIZ antibody | Organs/Tissues associated with anti-WIZ antibody |
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Antibody 
