NP_001278809.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
41,830 Da
NCBI Official Full Name
protein Wnt-2b isoform 3
NCBI Official Synonym Full Names
wingless-type MMTV integration site family, member 2B
NCBI Official Synonym Symbols
NCBI Protein Information
protein Wnt-2b; XWNT2, Xenopus, homolog of; wingless-type MMTV integration site family, member 13
UniProt Protein Name
Protein Wnt-2b
UniProt Synonym Protein Names
Protein Wnt-13
UniProt Synonym Gene Names
UniProt Entry Name
WNT2B_HUMAN
NCBI Summary for WNT2B
This gene encodes a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
UniProt Comments for WNT2B
WNT2B: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. May be involved in normal development or differentiation as well as in carcinogenesis. Belongs to the Wnt family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 1p13
Cellular Component: proteinaceous extracellular matrix; extracellular space; extracellular region
Molecular Function: frizzled binding
Biological Process: lens development in camera-type eye; neuron differentiation; Wnt receptor signaling pathway; cell fate commitment; male gonad development; chondrocyte differentiation; Wnt receptor signaling pathway through beta-catenin; cellular response to starvation; forebrain regionalization
Research Articles on WNT2B
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Products associated with anti-WNT2B antibody
Pathways associated with anti-WNT2B antibody
Diseases associated with anti-WNT2B antibody
Organs/Tissues associated with anti-WNT2B antibody
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