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anti-WNT7B antibody :: Rabbit anti-Human, Mouse WNT7B Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7045787
Unit / Price
0.05 mL  /  $120 +1 FREE 8GB USB
0.1 mL  /  $160 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

WNT7B, Polyclonal Antibody

★Popular Item★
 Also Known As   

WNT7B Antibody

 Product Synonym Names    Protein Wnt-7b; WNT7B
 Product Gene Name   

anti-WNT7B antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    601967
 3D Structure    ModBase 3D Structure for P56706
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Purity/Purification    Antigen Affinity Purified
 Form/Format    Liquid
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 Species    Human
 Immunogen    Recombinant human Protein Wnt-7b protein (C-230AA)
 Conjugate    Non-conjugated
 Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-26363
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-WNT7B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-WNT7B antibody

   Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity).
 Applications Tested/Suitable for anti-WNT7B antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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 Western Blot (WB) of anti-WNT7B antibody    Western blot
All lanes: WNT7B antibody at 2.41ug/ml+ Mouse small intestine tissue
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 39 kDa
Observed band size: 39 kDa

anti-WNT7B antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-WNT7B antibody    Immunohistochemistry of paraffin-embedded human ovarian cancer using MBS7045787 at dilution 1:100
anti-WNT7B antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-WNT7B antibody    Immunohistochemistry of paraffin-embedded human brain tissue using MBS7045787 at dilution 1:100
anti-WNT7B antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for WNT7B. It may not necessarily be applicable to this product.
 NCBI GI #    17505193
 NCBI GeneID    7477
 NCBI Accession #    NP_478679.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_058238.2 [Other Products]
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 UniProt Primary Accession #    P56706 [Other Products]
 UniProt Secondary Accession #    Q96Q12; B8A596 [Other Products]
 UniProt Related Accession #    P56706 [Other Products]
 Molecular Weight    39,327 Da
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 NCBI Official Full Name    protein Wnt-7b
 NCBI Official Synonym Full Names    Wnt family member 7B
 NCBI Official Symbol    WNT7B [Similar Products]
 NCBI Protein Information    protein Wnt-7b
 UniProt Protein Name    Protein Wnt-7b
 Protein Family    Protein
 UniProt Gene Name    WNT7B [Similar Products]
 UniProt Entry Name    WNT7B_HUMAN
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 NCBI Summary for WNT7B    This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Among members of the human WNT family, this gene product is most similar to WNT7A protein. [provided by RefSeq, Oct 2008]
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 UniProt Comments for WNT7B    WNT7B: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Belongs to the Wnt family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 22q13

Cellular Component: endoplasmic reticulum lumen; extracellular region; extracellular space; Golgi lumen; plasma membrane

Molecular Function: frizzled binding

Biological Process: cell fate commitment; cellular metabolic process; central nervous system vasculogenesis; embryonic organ development; establishment and/or maintenance of polarity of embryonic epithelium; fibroblast proliferation; forebrain regionalization; homeostatic process; in utero embryonic development; lung development; neuron differentiation; oxygen homeostasis; positive regulation of osteoblast differentiation; synapse organization and biogenesis; Wnt receptor signaling pathway; Wnt receptor signaling pathway through beta-catenin
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 Research Articles on WNT7B    1. Forced overexpression of Wnt7B with or without TGFB1 treatment increased Wnt5A protein expression in normal human smooth muscle cells and fibroblasts but not in Idiopathic Pulmonary Fibrosis myofibroblasts where Wnt5A was already highly expressed.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-WNT7B antibodyDiseases associated with anti-WNT7B antibody
 Products by Pathway  Pathway Diagram
 Basal Cell Carcinoma Pathway antibodies  Basal Cell Carcinoma Pathway Diagram
 Basal Cell Carcinoma Pathway antibodies  Basal Cell Carcinoma Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 DNA Damage Response (only ATM Dependent) Pathway antibodies  DNA Damage Response (only ATM Dependent) Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Melanogenesis Pathway antibodies  Melanogenesis Pathway Diagram
 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >15 publications with WNT7B and Disease Models, Animal
 Breast Neoplasms Antibodies  >12 publications with WNT7B and Breast Neoplasms
 Fibrosis Antibodies  >10 publications with WNT7B and Fibrosis
 Adenocarcinoma Antibodies  >8 publications with WNT7B and Adenocarcinoma
 Inflammation Antibodies  >8 publications with WNT7B and Inflammation
 Necrosis Antibodies  >6 publications with WNT7B and Necrosis
 Hyperplasia Antibodies  >5 publications with WNT7B and Hyperplasia
 Nervous System Malformations Antibodies  >3 publications with WNT7B and Nervous System Malformations
 Neoplasms, Experimental Antibodies  >3 publications with WNT7B and Neoplasms, Experimental
 Kidney Diseases Antibodies  >3 publications with WNT7B and Kidney Diseases
Organs/Tissues associated with anti-WNT7B antibody
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >35 publications with WNT7B and Bone
 Brain Antibodies  >34 publications with WNT7B and Brain
 Embryonic Tissue Antibodies  >33 publications with WNT7B and Embryonic Tissue
 Lung Antibodies  >31 publications with WNT7B and Lung
 Kidney Antibodies  >17 publications with WNT7B and Kidney
 Eye Antibodies  >15 publications with WNT7B and Eye
 Liver Antibodies  >8 publications with WNT7B and Liver
 Skin Antibodies  >8 publications with WNT7B and Skin
 Heart Antibodies  >6 publications with WNT7B and Heart
 Pancreas Antibodies  >5 publications with WNT7B and Pancreas
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