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anti-Xpnpep1 antibody :: Chicken X-Prolyl Aminopeptidase Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS616676 anti-Xpnpep1 antibody
Unit / Price
0.05 mg  /  $540 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

X-Prolyl Aminopeptidase (Xpnpep1), Polyclonal Antibody

 Also Known As   

X-Prolyl Aminopeptidase (Aminopeptidase P) 1, Soluble [XPNPEPL, X-Prolyl Aminopeptidase (Aminopeptidase P)-like]

 Product Synonym Names    Anti -X-Prolyl Aminopeptidase (Aminopeptidase P) 1, Soluble [XPNPEPL, X-Prolyl Aminopeptidase (Aminopeptidase P)-like]
 Product Gene Name   

anti-Xpnpep1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    chromosome: 19; Location: 19 D2; 19
 3D Structure    ModBase 3D Structure for Q3UKF5
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 Clonality    Polyclonal
 Isotype    IgY
 Host    Chicken
 Species Reactivity    Human, Mouse, Rat
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 Specificity    Recognizes human XPNPEPL. Species Crossreactivity: human, mouse and rat.
 Purity/Purification    Affinity Purified
Purified by affinity chromatography.
 Form/Format    Supplied as a liquid in PBS, pH 7.2. No preservative added. Glycerol free.
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 Immunogen    Synthetic peptide corresponding to aa401-623 of human XPNPEPL.
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 Preparation and Storage    May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of anti-Xpnpep1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-Xpnpep1 antibody

   X-prolyl aminopeptidase (EC 3.4.11.9) is a proline-specific metalloaminopeptidase that specifically catalyzes the removal of any unsubstituted N-terminal amino acid that is adjacent to a penultimate proline residue. Because of its specificity toward proline, it has been suggested that X-prolyl aminopeptidase is important in the maturation and degradation of peptide hormones, neuropeptides, and tachykinins, as well as in the digestion of otherwise resistant dietary protein fragments, thereby complementing the pancreatic peptidases. Deficiency of X-prolyl aminopeptidase results in excretion of large amounts of imino-oligopeptides in urine.
 Product Categories/Family for anti-Xpnpep1 antibody    Antibodies; Abs to Enzymes
 Applications Tested/Suitable for anti-Xpnpep1 antibody   

Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

 Application Notes for anti-Xpnpep1 antibody    Suitable for use in Western Blot, Immunohistochemistry, and Immunocytochemistry.
Dilution: Western Blot: 1:250
Immunohistochemistry: 1:100
Immunocytochemistry: 1:100
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NCBI/Uniprot data below describe general gene information for Xpnpep1. It may not necessarily be applicable to this product.
 NCBI GI #    94962412
 NCBI GeneID    170750
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 UniProt Primary Accession #    Q3UKF5 [Other Products]
 UniProt Related Accession #    Q3TL27; Q3UE92; Q3UKF5; Q6P1B1; Q8BKH1; Q8BV43; Q8VDK8 [Other Products]
 Molecular Weight    69,591 Da [Similar Products]
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 NCBI Official Full Name    X-prolyl aminopeptidase
 NCBI Official Synonym Full Names    X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
 NCBI Official Symbol    Xpnpep1 [Similar Products]
 NCBI Official Synonym Symbols   
D230045I08Rik; Xpnpep1
[Similar Products]
 NCBI Protein Information    xaa-Pro aminopeptidase 1; sAmp; X-Pro aminopeptidase 1; soluble aminopeptidase P; cytosolic aminopeptidase P; aminoacylproline aminopeptidase; X-prolyl aminopeptidase 1, soluble
 UniProt Protein Name    X-prolyl aminopeptidase
 UniProt Gene Name    Xpnpep1 [Similar Products]
 UniProt Entry Name    Q3UKF5_MOUSE
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 UniProt Comments for Xpnpep1    XPNPEP1: Contributes to the degradation of bradykinin. Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro. Belongs to the peptidase M24B family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Protease; EC 3.4.11.9

Cellular Component: cytoplasm; cytosol

Molecular Function: peptidase activity; protein homodimerization activity; metallopeptidase activity; hydrolase activity; manganese ion binding; metal ion binding; aminopeptidase activity

Biological Process: proteolysis
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-Xpnpep1 antibodyOrgans/Tissues associated with anti-Xpnpep1 antibody
 Disease Name  Pubmed Publications
 Hypertension Antibodies  >1 publications with Xpnpep1 and Hypertension
 Myocardial Infarction Antibodies  >1 publications with Xpnpep1 and Myocardial Infarction
 Fibrosis Antibodies  >1 publications with Xpnpep1 and Fibrosis
 Congenital Abnormalities Antibodies  >1 publications with Xpnpep1 and Congenital Abnormalities
 Kidney Diseases Antibodies  >1 publications with Xpnpep1 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1 publications with Xpnpep1 and Blood
 Liver Antibodies  >1 publications with Xpnpep1 and Liver
 Heart Antibodies  >1 publications with Xpnpep1 and Heart
 Kidney Antibodies  >1 publications with Xpnpep1 and Kidney
 Brain Antibodies  >1 publications with Xpnpep1 and Brain
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