NP_620780.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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Molecular Weight
69,486 Da
NCBI Official Full Name
X-ray repair cross-complementing protein 6
NCBI Official Synonym Full Names
X-ray repair cross complementing 6
NCBI Protein Information
X-ray repair cross-complementing protein 6
UniProt Protein Name
X-ray repair complementing defective repair in Chinese hamster cells 6, isoform CRA_a
UniProt Synonym Protein Names
X-ray repair complementing defective repair in Chinese hamster cells 6, isoform CRA_a
NCBI Summary for XRCC6
DNA targeting component of the DNA-dependent protein kinase complex DNA-PK, which plays a role in DNA double strand break repair [RGD, Feb 2006]
UniProt Comments for XRCC6
Ku70: a mini-chromosome maintenance protein, essential for the initiation of eukaryotic genome replication. Allows DNA to undergo a single round of replication per cell cycle. Required for the entry in S phase and for cell division.
Protein type: DNA repair, damage; DNA-binding; EC 3.6.4.-; EC 4.2.99.-; Helicase; Nuclear receptor co-regulator; RNA-binding
Chromosomal Location of Human Ortholog: 7q34
Cellular Component: cytoplasm; membrane; nuclear chromosome, telomeric region; nucleolus; nucleoplasm; nucleus; protein complex; transcription factor complex
Molecular Function: 5'-deoxyribose-5-phosphate lyase activity; ATP-dependent DNA helicase activity; cyclin binding; damaged DNA binding; double-stranded DNA binding; double-stranded telomeric DNA binding; protein binding; protein C-terminus binding; RNA binding; telomeric DNA binding
Biological Process: activation of innate immune response; brain development; cellular response to DNA damage stimulus; DNA duplex unwinding; double-strand break repair; double-strand break repair via nonhomologous end joining; negative regulation of transcription, DNA-dependent; positive regulation of neurogenesis; positive regulation of protein kinase activity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-templated; protein heterotetramerization; regulation of smooth muscle cell proliferation; response to ionizing radiation; telomere maintenance; V(D)J recombination
Research Articles on XRCC6
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Products associated with anti-XRCC6 antibody
Pathways associated with anti-XRCC6 antibody
Diseases associated with anti-XRCC6 antibody
Organs/Tissues associated with anti-XRCC6 antibody
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