NP_004303.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
39,667 Da
NCBI Official Full Name
arrestin-C
NCBI Official Synonym Full Names
arrestin 3 retinal (X-arrestin)
NCBI Official Synonym Symbols
NCBI Protein Information
arrestin-C
UniProt Protein Name
Arrestin-C
UniProt Synonym Protein Names
Cone arrestin; C-arrestin; cArr; Retinal cone arrestin-3; X-arrestin
UniProt Synonym Gene Names
UniProt Entry Name
ARRC_HUMAN
NCBI Summary for ARR3
The protein encoded by this gene is a non-visual arrestin which binds to agonist-activated, phosphorylated G protein-coupled receptors. This binding uncouples the receptor from the heterotrimeric G protein, resulting in termination of the G protein-coupled receptor signaling. The encoded protein also is a part of the centrosome, interacting with gamma-tubulin to help regulate proper centrosome function. [provided by RefSeq, May 2016]
UniProt Comments for ARR3
ARR3: May play a role in an as yet undefined retina-specific signal transduction. Could binds to photoactivated-phosphorylated red/green opsins. Belongs to the arrestin family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: Xcen-q21
Cellular Component: cytoplasm; photoreceptor inner segment; photoreceptor outer segment; synapse
Molecular Function: opsin binding; phosphoprotein binding; protein binding; protein domain specific binding
Biological Process: endocytosis; regulation of protein amino acid phosphorylation; signal transduction; visual perception
Research Articles on ARR3
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Pathways associated with anti-ARR3 antibody
Diseases associated with anti-ARR3 antibody
Organs/Tissues associated with anti-ARR3 antibody
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