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anti-XPNPEP1 antibody :: Rabbit anti-Human Xaa-Pro aminopeptidase 1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS1491510
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Xaa-Pro aminopeptidase 1 (XPNPEP1), Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-human Xaa-Pro aminopeptidase 1 polyclonal Antibody

 Product Synonym Names    Aminoacylproline aminopeptidase; Cytosolic aminopeptidase P; Soluble aminopeptidase P; sAmp; X-Pro aminopeptidase 1; X-prolyl aminopeptidase 1; soluble; XPNPEP1; XPNPEPL; XPNPEPL1
 Product Gene Name   

anti-XPNPEP1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    602443
 3D Structure    ModBase 3D Structure for Q9NQW7
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Caprylic Acid Ammonium Sulfate Precipitation Purified
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 Storage Buffer    Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Conjugate    Non-conjugated
 Immunogen    Recombinant human Xaa-Pro aminopeptidase 1 protein
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-109031 / sc-109032
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-XPNPEP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-XPNPEP1 antibody

   Contributes to the degradation of bradykinin. Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro.
 Applications Tested/Suitable for anti-XPNPEP1 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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 Western Blot (WB) of anti-XPNPEP1 antibody    Western blot
All lanes: Xaa-Pro aminopeptidase 1 antibody at 8ug/ml
Lane 1: Mouse small intestine tissue
Lane 2: Mouse stomach tissue
Lane 3: Mouse kidney tissue
Secondary
Goat polyclonal to Rabbit IgG at 1/10000 dilution
Predicted band size: 70,68,75,73 kDa
Observed band size: 70 kDa

anti-XPNPEP1 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-XPNPEP1 antibody    Immunohistochemistry of paraffin-embedded human colon cancer using MBS1491510 at dilution of 1:100
anti-XPNPEP1 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for XPNPEP1. It may not necessarily be applicable to this product.
 NCBI GI #    264681565
 NCBI GeneID    7511
 NCBI Accession #    NP_001161076.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001167604.1 [Other Products]
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 UniProt Primary Accession #    Q9NQW7 [Other Products]
 UniProt Secondary Accession #    O15250; Q53EX6; Q8N3Q0; Q96D23; A8K071; G5E9Y2; G8JLB2 [Other Products]
 UniProt Related Accession #    Q9NQW7 [Other Products]
 Molecular Weight    72,107 Da [Similar Products]
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 NCBI Official Full Name    xaa-Pro aminopeptidase 1 isoform 2
 NCBI Official Synonym Full Names    X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
 NCBI Official Symbol    XPNPEP1 [Similar Products]
 NCBI Official Synonym Symbols   
APP1; SAMP; XPNPEP; XPNPEPL; XPNPEPL1
[Similar Products]
 NCBI Protein Information    xaa-Pro aminopeptidase 1
 UniProt Protein Name    Xaa-Pro aminopeptidase 1
 UniProt Synonym Protein Names   
Aminoacylproline aminopeptidase; Cytosolic aminopeptidase P; Soluble aminopeptidase P; sAmp; X-Pro aminopeptidase 1; X-prolyl aminopeptidase 1, soluble
 Protein Family    Xaa-Pro aminopeptidase
 UniProt Gene Name    XPNPEP1 [Similar Products]
 UniProt Synonym Gene Names    sAmp [Similar Products]
 UniProt Entry Name    XPP1_HUMAN
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 NCBI Summary for XPNPEP1    This gene encodes the cytosolic form of a metalloaminopeptidase that catalyzes the cleavage of the N-terminal amino acid adjacent to a proline residue. The gene product may play a role in degradation and maturation of tachykinins, neuropeptides, and peptide hormones. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2009]
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 UniProt Comments for XPNPEP1    XPNPEP1: Contributes to the degradation of bradykinin. Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro. Belongs to the peptidase M24B family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.11.9; Protease

Chromosomal Location of Human Ortholog: 10q25.3

Cellular Component: cytoplasm

Molecular Function: aminopeptidase activity; manganese ion binding; protein homodimerization activity

Biological Process: proteolysis
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 Research Articles on XPNPEP1    1. Observational study of gene-disease association, gene-gene interaction, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-XPNPEP1 antibodyOrgans/Tissues associated with anti-XPNPEP1 antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >3 publications with XPNPEP1 and Nervous System Diseases
 Inflammation Antibodies  >2 publications with XPNPEP1 and Inflammation
 Cardiovascular Diseases Antibodies  >1 publications with XPNPEP1 and Cardiovascular Diseases
 Kidney Diseases Antibodies  >1 publications with XPNPEP1 and Kidney Diseases
 Prenatal Exposure Delayed Effects Antibodies  >1 publications with XPNPEP1 and Prenatal Exposure Delayed Effects
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >5 publications with XPNPEP1 and Brain
 Blood Antibodies  >3 publications with XPNPEP1 and Blood
 Liver Antibodies  >3 publications with XPNPEP1 and Liver
 Heart Antibodies  >2 publications with XPNPEP1 and Heart
 Kidney Antibodies  >1 publications with XPNPEP1 and Kidney
 Vascular Antibodies  >1 publications with XPNPEP1 and Vascular
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