NP_851321.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
zinc-activated ligand-gated ion channel
NCBI Official Synonym Full Names
zinc activated ligand-gated ion channel
NCBI Protein Information
zinc-activated ligand-gated ion channel
UniProt Protein Name
Zinc-activated ligand-gated ion channel
UniProt Synonym Protein Names
Ligand-gated ion channel zinc-activated 1; Ligand-gated ion-channel receptor L2
UniProt Synonym Gene Names
UniProt Entry Name
ZACN_HUMAN
NCBI Summary for ZACN
LGICZ1 is a zinc-activated ligand-gated ion channel that defines a new subgroup of the cysteine-loop superfamily of ligand-gated ion channels (Davies et al., 2003 [PubMed 12381728]).[supplied by OMIM, Mar 2008]
UniProt Comments for ZACN
ZACN: Zinc-activated ligand-gated ion channel. Belongs to the ligand-gated ion channel (TC 1.A.9) family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 17q25.3
Cellular Component: plasma membrane; integral to membrane
Molecular Function: zinc ion binding; ligand-gated ion channel activity; extracellular ligand-gated ion channel activity
Biological Process: response to zinc ion
Product References and Citations for anti-ZACN antibody
Houtani, T., et al. Biochem. Biophys. Res. Commun. 335(2):277-285(2005) Davies, P.A., et al. J. Biol. Chem. 278(2):712-717(2003)
Research Articles on ZACN
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Diseases associated with anti-ZACN antibody
Organs/Tissues associated with anti-ZACN antibody
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